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Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity

PLoS pathogens, 2019-01, Vol.15 (1), p.e1007515

2019

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The alphavirus nonstructural protein 2 NTPase induces a host translational shut-off through phosphorylation of eEF2 via cAMP-PKA-eEF2K signaling

PLoS pathogens, 2023-02, Vol.19 (2), p.e1011179-e1011179

2023

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Defective Interfering Viral Particle Treatment Reduces Clinical Signs and Protects Hamsters from Lethal Nipah Virus Disease

mBio, 2022-04, Vol.13 (2), p.e0329421-e0329421

2022

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Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases

PloS one, 2019-12, Vol.14 (12), p.e0226415-e0226415

2019

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Characterization of synthetic Chikungunya viruses based on the consensus sequence of recent E1-226V isolates

PloS one, 2013-08, Vol.8 (8), p.e71047

2013

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Replicon particle vaccination induces non-neutralizing anti-nucleoprotein antibody-mediated control of Crimean-Congo hemorrhagic fever virus

npj vaccines, 2024-05, Vol.9 (1), p.88-88, Article 88

2024

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Stress granule components G3BP1 and G3BP2 play a proviral role early in Chikungunya virus replication

Journal of virology, 2015-04, Vol.89 (8), p.4457-4469

2015

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Molecular Insights into Crimean-Congo Hemorrhagic Fever Virus

Viruses, 2016-04, Vol.8 (4), p.106-106

2016

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Inhibition of dengue and chikungunya virus infections by RIG-I-mediated type I interferon-independent stimulation of the innate antiviral response

Journal of virology, 2014-04, Vol.88 (8), p.4180-4194

2014

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Fluorescent Crimean-Congo hemorrhagic fever virus illuminates tissue tropism patterns and identifies early mononuclear phagocytic cell targets in Ifnar-/- mice

PLoS pathogens, 2019-12, Vol.15 (12), p.e1008183-e1008183

2019

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A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins

Journal of virology, 2015-08, Vol.89 (16), p.8318-8333

2015

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ISG15: It's Complicated

Journal of molecular biology, 2019-10, Vol.431 (21), p.4203-4216

2019

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The Structure and Immune Regulatory Implications of the Ubiquitin-Like Tandem Domain Within an Avian 2'-5' Oligoadenylate Synthetase-Like Protein

Frontiers in immunology, 2022-01, Vol.12, p.794664-794664

2022

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Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection

mBio, 2019-07, Vol.10 (4)

2019

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Single-dose replicon particle vaccine provides complete protection against Crimean-Congo hemorrhagic fever virus in mice

Emerging microbes & infections, 2019-01, Vol.8 (1), p.575-578

2019

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How ISG15 combats viral infection

Virus research, 2020-09, Vol.286, p.198036-198036, Article 198036

2020

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The S Genome Segment Is Sufficient to Maintain Pathogenicity in Intra-Clade Lassa Virus Reassortants in a Guinea Pig Model

Frontiers in cellular and infection microbiology, 2018-07, Vol.8, p.240-240

2018

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Viral RNA and infectious virus in mucosal specimens from guinea pigs modelling early phases of lethal and non-lethal Lassa fever

Emerging microbes & infections, 2022-12, Vol.11 (1), p.1390-1393

2022

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Single-dose mucosal replicon-particle vaccine protects against lethal Nipah virus infection up to 3 days after vaccination

Science advances, 2023-08, Vol.9 (31), p.eadh4057-eadh4057

2023

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The Crimean-Congo Hemorrhagic Fever Virus NSm Protein is Dispensable for Growth In Vitro and Disease in Ifnar -/- Mice

Microorganisms (Basel), 2020-05, Vol.8 (5), p.775

2020

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Identification of 2′-deoxy-2′-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus

Antiviral research, 2017-11, Vol.147 (C), p.91-99

2017

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Temporal SILAC-based quantitative proteomics identifies host factors involved in chikungunya virus replication

Proteomics (Weinheim), 2015-07, Vol.15 (13), p.2267-2280

2015

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Evaluation of a Single-Dose Nucleoside-Modified Messenger RNA Vaccine Encoding Hendra Virus-Soluble Glycoprotein Against Lethal Nipah virus Challenge in Syrian Hamsters

The Journal of infectious diseases, 2020-05, Vol.221 (Supplement_4), p.S493-S498

2020

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Griffithsin Inhibits Nipah Virus Entry and Fusion and Can Protect Syrian Golden Hamsters From Lethal Nipah Virus Challenge

The Journal of infectious diseases, 2020-05, Vol.221 (Supplement_4), p.S480-S492

2020

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Lassa virus replicon particle vaccine protects strain 13/N guinea pigs against challenge with geographically and genetically diverse viral strains

The Journal of infectious diseases, 2022-11, Vol.226 (9), p.1545-1550

2022

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Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity

The alphavirus nonstructural protein 2 NTPase induces a host translational shut-off through phosphorylation of eEF2 via cAMP-PKA-eEF2K signaling

Defective Interfering Viral Particle Treatment Reduces Clinical Signs and Protects Hamsters from Lethal Nipah Virus Disease

Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases

Characterization of synthetic Chikungunya viruses based on the consensus sequence of recent E1-226V isolates

Replicon particle vaccination induces non-neutralizing anti-nucleoprotein antibody-mediated control of Crimean-Congo hemorrhagic fever virus

Stress granule components G3BP1 and G3BP2 play a proviral role early in Chikungunya virus replication

Molecular Insights into Crimean-Congo Hemorrhagic Fever Virus

Inhibition of dengue and chikungunya virus infections by RIG-I-mediated type I interferon-independent stimulation of the innate antiviral response

Fluorescent Crimean-Congo hemorrhagic fever virus illuminates tissue tropism patterns and identifies early mononuclear phagocytic cell targets in Ifnar-/- mice

A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins

ISG15: It's Complicated

The Structure and Immune Regulatory Implications of the Ubiquitin-Like Tandem Domain Within an Avian 2'-5' Oligoadenylate Synthetase-Like Protein

Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection

Single-dose replicon particle vaccine provides complete protection against Crimean-Congo hemorrhagic fever virus in mice

How ISG15 combats viral infection

The S Genome Segment Is Sufficient to Maintain Pathogenicity in Intra-Clade Lassa Virus Reassortants in a Guinea Pig Model

Viral RNA and infectious virus in mucosal specimens from guinea pigs modelling early phases of lethal and non-lethal Lassa fever

Single-dose mucosal replicon-particle vaccine protects against lethal Nipah virus infection up to 3 days after vaccination

The Crimean-Congo Hemorrhagic Fever Virus NSm Protein is Dispensable for Growth In Vitro and Disease in Ifnar -/- Mice

Identification of 2′-deoxy-2′-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus

Temporal SILAC-based quantitative proteomics identifies host factors involved in chikungunya virus replication

Evaluation of a Single-Dose Nucleoside-Modified Messenger RNA Vaccine Encoding Hendra Virus-Soluble Glycoprotein Against Lethal Nipah virus Challenge in Syrian Hamsters

Griffithsin Inhibits Nipah Virus Entry and Fusion and Can Protect Syrian Golden Hamsters From Lethal Nipah Virus Challenge

Lassa virus replicon particle vaccine protects strain 13/N guinea pigs against challenge with geographically and genetically diverse viral strains

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