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Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity

PLoS pathogens, 2019-01, Vol.15 (1), p.e1007515

2019

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The alphavirus nonstructural protein 2 NTPase induces a host translational shut-off through phosphorylation of eEF2 via cAMP-PKA-eEF2K signaling

PLoS pathogens, 2023-02, Vol.19 (2), p.e1011179-e1011179

2023

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Defective Interfering Viral Particle Treatment Reduces Clinical Signs and Protects Hamsters from Lethal Nipah Virus Disease

mBio, 2022-04, Vol.13 (2), p.e0329421-e0329421

2022

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Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases

PloS one, 2019-12, Vol.14 (12), p.e0226415-e0226415

2019

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Characterization of synthetic Chikungunya viruses based on the consensus sequence of recent E1-226V isolates

PloS one, 2013-08, Vol.8 (8), p.e71047

2013

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Replicon particle vaccination induces non-neutralizing anti-nucleoprotein antibody-mediated control of Crimean-Congo hemorrhagic fever virus

npj vaccines, 2024-05, Vol.9 (1), p.88-88, Article 88

2024

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Stress granule components G3BP1 and G3BP2 play a proviral role early in Chikungunya virus replication

Journal of virology, 2015-04, Vol.89 (8), p.4457-4469

2015

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Crimean Congo hemorrhagic fever virus nucleoprotein and GP38 subunit vaccine combination prevents morbidity in mice

npj vaccines, 2024-08, Vol.9 (1), p.148-16

2024

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Molecular Insights into Crimean-Congo Hemorrhagic Fever Virus

Viruses, 2016-04, Vol.8 (4), p.106-106

2016

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Inhibition of dengue and chikungunya virus infections by RIG-I-mediated type I interferon-independent stimulation of the innate antiviral response

Journal of virology, 2014-04, Vol.88 (8), p.4180-4194

2014

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Fluorescent Crimean-Congo hemorrhagic fever virus illuminates tissue tropism patterns and identifies early mononuclear phagocytic cell targets in Ifnar-/- mice

PLoS pathogens, 2019-12, Vol.15 (12), p.e1008183-e1008183

2019

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A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins

Journal of virology, 2015-08, Vol.89 (16), p.8318-8333

2015

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ISG15: It's Complicated

Journal of molecular biology, 2019-10, Vol.431 (21), p.4203-4216

2019

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Single-dose replicon particle vaccine provides complete protection against Crimean-Congo hemorrhagic fever virus in mice

Emerging microbes & infections, 2019-01, Vol.8 (1), p.575-578

2019

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Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection

mBio, 2019-07, Vol.10 (4)

2019

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The Structure and Immune Regulatory Implications of the Ubiquitin-Like Tandem Domain Within an Avian 2'-5' Oligoadenylate Synthetase-Like Protein

Frontiers in immunology, 2022-01, Vol.12, p.794664-794664

2022

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How ISG15 combats viral infection

Virus research, 2020-09, Vol.286, p.198036-198036, Article 198036

2020

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Single-dose mucosal replicon-particle vaccine protects against lethal Nipah virus infection up to 3 days after vaccination

Science advances, 2023-08, Vol.9 (31), p.eadh4057-eadh4057

2023

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Viral RNA and infectious virus in mucosal specimens from guinea pigs modelling early phases of lethal and non-lethal Lassa fever

Emerging microbes & infections, 2022-12, Vol.11 (1), p.1390-1393

2022

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The S Genome Segment Is Sufficient to Maintain Pathogenicity in Intra-Clade Lassa Virus Reassortants in a Guinea Pig Model

Frontiers in cellular and infection microbiology, 2018-07, Vol.8, p.240-240

2018

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The Crimean-Congo Hemorrhagic Fever Virus NSm Protein is Dispensable for Growth In Vitro and Disease in Ifnar -/- Mice

Microorganisms (Basel), 2020-05, Vol.8 (5), p.775

2020

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Temporal SILAC-based quantitative proteomics identifies host factors involved in chikungunya virus replication

Proteomics (Weinheim), 2015-07, Vol.15 (13), p.2267-2280

2015

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Evaluation of a Single-Dose Nucleoside-Modified Messenger RNA Vaccine Encoding Hendra Virus-Soluble Glycoprotein Against Lethal Nipah virus Challenge in Syrian Hamsters

The Journal of infectious diseases, 2020-05, Vol.221 (Supplement_4), p.S493-S498

2020

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Griffithsin Inhibits Nipah Virus Entry and Fusion and Can Protect Syrian Golden Hamsters From Lethal Nipah Virus Challenge

The Journal of infectious diseases, 2020-05, Vol.221 (Supplement_4), p.S480-S492

2020

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Crimean-Congo Hemorrhagic Fever Virus Suppresses Innate Immune Responses via a Ubiquitin and ISG15 Specific Protease

Cell reports (Cambridge), 2017-09, Vol.20 (10), p.2396-2407

2017

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Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity

The alphavirus nonstructural protein 2 NTPase induces a host translational shut-off through phosphorylation of eEF2 via cAMP-PKA-eEF2K signaling

Defective Interfering Viral Particle Treatment Reduces Clinical Signs and Protects Hamsters from Lethal Nipah Virus Disease

Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases

Characterization of synthetic Chikungunya viruses based on the consensus sequence of recent E1-226V isolates

Replicon particle vaccination induces non-neutralizing anti-nucleoprotein antibody-mediated control of Crimean-Congo hemorrhagic fever virus

Stress granule components G3BP1 and G3BP2 play a proviral role early in Chikungunya virus replication

Crimean Congo hemorrhagic fever virus nucleoprotein and GP38 subunit vaccine combination prevents morbidity in mice

Molecular Insights into Crimean-Congo Hemorrhagic Fever Virus

Inhibition of dengue and chikungunya virus infections by RIG-I-mediated type I interferon-independent stimulation of the innate antiviral response

Fluorescent Crimean-Congo hemorrhagic fever virus illuminates tissue tropism patterns and identifies early mononuclear phagocytic cell targets in Ifnar-/- mice

A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins

ISG15: It's Complicated

Single-dose replicon particle vaccine provides complete protection against Crimean-Congo hemorrhagic fever virus in mice

Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection

The Structure and Immune Regulatory Implications of the Ubiquitin-Like Tandem Domain Within an Avian 2'-5' Oligoadenylate Synthetase-Like Protein

How ISG15 combats viral infection

Single-dose mucosal replicon-particle vaccine protects against lethal Nipah virus infection up to 3 days after vaccination

Viral RNA and infectious virus in mucosal specimens from guinea pigs modelling early phases of lethal and non-lethal Lassa fever

The S Genome Segment Is Sufficient to Maintain Pathogenicity in Intra-Clade Lassa Virus Reassortants in a Guinea Pig Model

The Crimean-Congo Hemorrhagic Fever Virus NSm Protein is Dispensable for Growth In Vitro and Disease in Ifnar -/- Mice

Temporal SILAC-based quantitative proteomics identifies host factors involved in chikungunya virus replication

Evaluation of a Single-Dose Nucleoside-Modified Messenger RNA Vaccine Encoding Hendra Virus-Soluble Glycoprotein Against Lethal Nipah virus Challenge in Syrian Hamsters

Griffithsin Inhibits Nipah Virus Entry and Fusion and Can Protect Syrian Golden Hamsters From Lethal Nipah Virus Challenge

Crimean-Congo Hemorrhagic Fever Virus Suppresses Innate Immune Responses via a Ubiquitin and ISG15 Specific Protease

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