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The alphavirus nonstructural protein 2 NTPase induces a host translational shut-off through phosphorylation of eEF2 via cAMP-PKA-eEF2K signaling

PLoS pathogens, 2023-02, Vol.19 (2), p.e1011179-e1011179

2023

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Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity

PLoS pathogens, 2019-01, Vol.15 (1), p.e1007515

2019

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Defective Interfering Viral Particle Treatment Reduces Clinical Signs and Protects Hamsters from Lethal Nipah Virus Disease

mBio, 2022-04, Vol.13 (2), p.e0329421-e0329421

2022

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Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases

PloS one, 2019-12, Vol.14 (12), p.e0226415-e0226415

2019

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Characterization of synthetic Chikungunya viruses based on the consensus sequence of recent E1-226V isolates

PloS one, 2013-08, Vol.8 (8), p.e71047

2013

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Molecular Insights into Crimean-Congo Hemorrhagic Fever Virus

Viruses, 2016-04, Vol.8 (4), p.106-106

2016

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Fluorescent Crimean-Congo hemorrhagic fever virus illuminates tissue tropism patterns and identifies early mononuclear phagocytic cell targets in Ifnar-/- mice

PLoS pathogens, 2019-12, Vol.15 (12), p.e1008183-e1008183

2019

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Replicon particle vaccination induces non-neutralizing anti-nucleoprotein antibody-mediated control of Crimean-Congo hemorrhagic fever virus

npj vaccines, 2024-05, Vol.9 (1), p.88-88, Article 88

2024

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Stress granule components G3BP1 and G3BP2 play a proviral role early in Chikungunya virus replication

Journal of virology, 2015-04, Vol.89 (8), p.4457-4469

2015

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Crimean Congo hemorrhagic fever virus nucleoprotein and GP38 subunit vaccine combination prevents morbidity in mice

npj vaccines, 2024-08, Vol.9 (1), p.148-16

2024

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Identification of 2′-deoxy-2′-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus

Antiviral research, 2017-11, Vol.147 (C), p.91-99

2017

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Inhibition of dengue and chikungunya virus infections by RIG-I-mediated type I interferon-independent stimulation of the innate antiviral response

Journal of virology, 2014-04, Vol.88 (8), p.4180-4194

2014

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Vaccination with the Crimean-Congo hemorrhagic fever virus viral replicon vaccine induces NP-based T-cell activation and antibodies possessing Fc-mediated effector functions

Frontiers in cellular and infection microbiology, 2023-08, Vol.13, p.1233148-1233148

2023

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The Structure and Immune Regulatory Implications of the Ubiquitin-Like Tandem Domain Within an Avian 2'-5' Oligoadenylate Synthetase-Like Protein

Frontiers in immunology, 2022-01, Vol.12, p.794664-794664

2022

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A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins

Journal of virology, 2015-08, Vol.89 (16), p.8318-8333

2015

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The development of adaptive skills in young people with Down syndrome

Journal of intellectual disability research, 2010-11, Vol.54 (11), p.943-954

2010

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Single-dose replicon particle vaccine provides complete protection against Crimean-Congo hemorrhagic fever virus in mice

Emerging microbes & infections, 2019-01, Vol.8 (1), p.575-578

2019

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Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection

mBio, 2019-07, Vol.10 (4)

2019

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ISG15: It's Complicated

Journal of molecular biology, 2019-10, Vol.431 (21), p.4203-4216

2019

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The Crimean-Congo Hemorrhagic Fever Virus NSm Protein is Dispensable for Growth In Vitro and Disease in Ifnar -/- Mice

Microorganisms (Basel), 2020-05, Vol.8 (5), p.775

2020

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The S Genome Segment Is Sufficient to Maintain Pathogenicity in Intra-Clade Lassa Virus Reassortants in a Guinea Pig Model

Frontiers in cellular and infection microbiology, 2018-07, Vol.8, p.240-240

2018

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How ISG15 combats viral infection

Virus research, 2020-09, Vol.286, p.198036-198036, Article 198036

2020

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Single-dose mucosal replicon-particle vaccine protects against lethal Nipah virus infection up to 3 days after vaccination

Science advances, 2023-08, Vol.9 (31), p.eadh4057-eadh4057

2023

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Viral RNA and infectious virus in mucosal specimens from guinea pigs modelling early phases of lethal and non-lethal Lassa fever

Emerging microbes & infections, 2022-12, Vol.11 (1), p.1390-1393

2022

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A single mutation in Crimean-Congo hemorrhagic fever virus discovered in ticks impairs infectivity in human cells

eLife, 2020-10, Vol.9

2020

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The alphavirus nonstructural protein 2 NTPase induces a host translational shut-off through phosphorylation of eEF2 via cAMP-PKA-eEF2K signaling

Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity

Defective Interfering Viral Particle Treatment Reduces Clinical Signs and Protects Hamsters from Lethal Nipah Virus Disease

Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases

Characterization of synthetic Chikungunya viruses based on the consensus sequence of recent E1-226V isolates

Molecular Insights into Crimean-Congo Hemorrhagic Fever Virus

Fluorescent Crimean-Congo hemorrhagic fever virus illuminates tissue tropism patterns and identifies early mononuclear phagocytic cell targets in Ifnar-/- mice

Replicon particle vaccination induces non-neutralizing anti-nucleoprotein antibody-mediated control of Crimean-Congo hemorrhagic fever virus

Stress granule components G3BP1 and G3BP2 play a proviral role early in Chikungunya virus replication

Crimean Congo hemorrhagic fever virus nucleoprotein and GP38 subunit vaccine combination prevents morbidity in mice

Identification of 2′-deoxy-2′-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus

Inhibition of dengue and chikungunya virus infections by RIG-I-mediated type I interferon-independent stimulation of the innate antiviral response

Vaccination with the Crimean-Congo hemorrhagic fever virus viral replicon vaccine induces NP-based T-cell activation and antibodies possessing Fc-mediated effector functions

The Structure and Immune Regulatory Implications of the Ubiquitin-Like Tandem Domain Within an Avian 2'-5' Oligoadenylate Synthetase-Like Protein

A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins

The development of adaptive skills in young people with Down syndrome

Single-dose replicon particle vaccine provides complete protection against Crimean-Congo hemorrhagic fever virus in mice

Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection

ISG15: It's Complicated

The Crimean-Congo Hemorrhagic Fever Virus NSm Protein is Dispensable for Growth In Vitro and Disease in Ifnar -/- Mice

The S Genome Segment Is Sufficient to Maintain Pathogenicity in Intra-Clade Lassa Virus Reassortants in a Guinea Pig Model

How ISG15 combats viral infection

Single-dose mucosal replicon-particle vaccine protects against lethal Nipah virus infection up to 3 days after vaccination

Viral RNA and infectious virus in mucosal specimens from guinea pigs modelling early phases of lethal and non-lethal Lassa fever

A single mutation in Crimean-Congo hemorrhagic fever virus discovered in ticks impairs infectivity in human cells

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