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Metabolomics approaches for discovering biomarkers of drug-induced hepatotoxicity and nephrotoxicity

Toxicology and applied pharmacology, 2010-03, Vol.243 (2), p.154-166

2010

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Translational biomarkers of acetaminophen-induced acute liver injury

Archives of Toxicology. Archiv für Toxikologie, 2015-09, Vol.89 (9), p.1497-1522

2015

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Metabonomics evaluation of urine from rats given acute and chronic doses of acetaminophen using NMR and UPLC/MS

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008-08, Vol.871 (2), p.328-340

2008

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Metabolomics evaluation of the effects of green tea extract on acetaminophen-induced hepatotoxicity in mice

Food and chemical toxicology, 2013-12, Vol.62, p.707-721

2013

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Modification of Norfloxacin by a Microbacterium sp. Strain Isolated from a Wastewater Treatment Plant

Applied and Environmental Microbiology, 2011-09, Vol.77 (17), p.6100-6108

2011

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Metabolomics Analysis of Urine Samples from Children after Acetaminophen Overdose

Metabolites, 2017-09, Vol.7 (3), p.46

2017

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Metabonomics evaluations of age-related changes in the urinary compositions of male Sprague Dawley rats and effects of data normalization methods on statistical and quantitative analysis

BMC bioinformatics, 2007-11, Vol.8 Suppl 7 (S7), p.S3-S3, Article S3

2007

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MALDI imaging mass spectrometry: an emerging tool in neurology

Metabolic brain disease, 2022, Vol.37 (1), p.105-121

2022

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Metabolomics Test Materials for Quality Control: A Study of a Urine Materials Suite

Metabolites, 2019-11, Vol.9 (11), p.270

2019

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Evaluations of the trans-sulfuration pathway in multiple liver toxicity studies

Toxicology and applied pharmacology, 2009-02, Vol.235 (1), p.25-32

2009

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Serum metabolomic profiles from patients with acute kidney injury: A pilot study

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012-04, Vol.893-894, p.107-113

2012

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Modeling chemical interaction profiles: II. Molecular docking, spectral data-activity relationship, and structure-activity relationship models for potent and weak inhibitors of cytochrome P450 CYP3A4 isozyme

Molecules (Basel, Switzerland), 2012-03, Vol.17 (3), p.3407-3460

2012

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Identification of a metabolic biomarker panel in rats for prediction of acute and idiosyncratic hepatotoxicity

Computational and structural biotechnology journal, 2014-07, Vol.10 (17), p.78-89

2014

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Modeling chemical interaction profiles: I. Spectral data-activity relationship and structure-activity relationship models for inhibitors and non-inhibitors of cytochrome P450 CYP3A4 and CYP2D6 isozymes

Molecules (Basel, Switzerland), 2012-03, Vol.17 (3), p.3383-3406

2012

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Stability of the Human Plasma Proteome to Pre-analytical Variability as Assessed by an Aptamer-Based Approach

Journal of proteome research, 2019-10, Vol.18 (10), p.3661-3670

2019

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An Integrated Analysis of Metabolites, Peptides, and Inflammation Biomarkers for Assessment of Preanalytical Variability of Human Plasma

Journal of proteome research, 2019-06, Vol.18 (6), p.2411-2421

2019

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Biotransformation of quinazoline and phthalazine by Aspergillus niger

Journal of bioscience and bioengineering, 2011-03, Vol.111 (3), p.333-335

2011

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The Role of Metabolic Biomarkers in Drug Toxicity Studies

Toxicology mechanisms and methods, 2008-01, Vol.18 (4), p.301-311

2008

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Dose-response analysis of epigenetic, metabolic, and apical endpoints after short-term exposure to experimental hepatotoxicants

Food and chemical toxicology, 2017-11, Vol.109 (Pt 1), p.690-702

2017

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Evaluating effects of penicillin treatment on the metabolome of rats

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013-08, Vol.932, p.134-143

2013

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Global metabolic profiling and its role in systems biology to advance personalized medicine in the 21st Century

Expert review of molecular diagnostics, 2007-05, Vol.7 (3), p.247-259

Schnackenberg, Laura K

2007

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Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury

Current protocols, 2022-07, Vol.2 (7), p.e478-n/a

2022

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Interaction of dietary resveratrol with animal-associated bacteria

FEMS microbiology letters, 2009-08, Vol.297 (2), p.266-273

2009

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Metabonomics of acute kidney injury in children after cardiac surgery

Pediatric nephrology (Berlin, West), 2008-06, Vol.23 (6), p.977-984

2008

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Early metabolomics changes in heart and plasma during chronic doxorubicin treatment in B6C3F1 mice

Journal of applied toxicology, 2016-11, Vol.36 (11), p.1486-1495

2016

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Metabolomics approaches for discovering biomarkers of drug-induced hepatotoxicity and nephrotoxicity

Translational biomarkers of acetaminophen-induced acute liver injury

Metabonomics evaluation of urine from rats given acute and chronic doses of acetaminophen using NMR and UPLC/MS

Metabolomics evaluation of the effects of green tea extract on acetaminophen-induced hepatotoxicity in mice

Modification of Norfloxacin by a Microbacterium sp. Strain Isolated from a Wastewater Treatment Plant

Metabolomics Analysis of Urine Samples from Children after Acetaminophen Overdose

Metabonomics evaluations of age-related changes in the urinary compositions of male Sprague Dawley rats and effects of data normalization methods on statistical and quantitative analysis

MALDI imaging mass spectrometry: an emerging tool in neurology

Metabolomics Test Materials for Quality Control: A Study of a Urine Materials Suite

Evaluations of the trans-sulfuration pathway in multiple liver toxicity studies

Serum metabolomic profiles from patients with acute kidney injury: A pilot study

Modeling chemical interaction profiles: II. Molecular docking, spectral data-activity relationship, and structure-activity relationship models for potent and weak inhibitors of cytochrome P450 CYP3A4 isozyme

Identification of a metabolic biomarker panel in rats for prediction of acute and idiosyncratic hepatotoxicity

Modeling chemical interaction profiles: I. Spectral data-activity relationship and structure-activity relationship models for inhibitors and non-inhibitors of cytochrome P450 CYP3A4 and CYP2D6 isozymes

Stability of the Human Plasma Proteome to Pre-analytical Variability as Assessed by an Aptamer-Based Approach

An Integrated Analysis of Metabolites, Peptides, and Inflammation Biomarkers for Assessment of Preanalytical Variability of Human Plasma

Biotransformation of quinazoline and phthalazine by Aspergillus niger

The Role of Metabolic Biomarkers in Drug Toxicity Studies

Dose-response analysis of epigenetic, metabolic, and apical endpoints after short-term exposure to experimental hepatotoxicants

Evaluating effects of penicillin treatment on the metabolome of rats

Global metabolic profiling and its role in systems biology to advance personalized medicine in the 21st Century

Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury

Interaction of dietary resveratrol with animal-associated bacteria

Metabonomics of acute kidney injury in children after cardiac surgery

Early metabolomics changes in heart and plasma during chronic doxorubicin treatment in B6C3F1 mice

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