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The IDIP framework for assessing protein function and its application to the prion protein

Biological reviews of the Cambridge Philosophical Society, 2021-10, Vol.96 (5), p.1907-1932

2021

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A single protective polymorphism in the prion protein blocks cross‐species prion replication in cultured cells

Journal of neurochemistry, 2023-04, Vol.165 (2), p.230-245

2023

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Loss of prion protein control of glucose metabolism promotes neurodegeneration in model of prion diseases

PLoS pathogens, 2021-10, Vol.17 (10), p.e1009991-e1009991

2021

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Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers

eLife, 2017-06, Vol.6

2017

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Proteome-wide identification of mycobacterial pupylation targets

Molecular systems biology, 2010, Vol.6 (1), p.386-n/a

2010

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The CNS glycoprotein Shadoo has PrPC-like protective properties and displays reduced levels in prion infections

The EMBO journal, 2007-09, Vol.26 (17), p.4038-4050

2007

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Endoproteolytic processing of the mammalian prion glycoprotein family

The FEBS journal, 2014-02, Vol.281 (3), p.862-876

2014

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Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration

Biochemical journal, 2016-08, Vol.473 (16), p.2531-2544

2016

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Drug Repositioning for Alzheimer's Disease Based on Systematic 'omics' Data Mining

PloS one, 2016-12, Vol.11 (12), p.e0168812-e0168812

2016

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Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation

EMBO molecular medicine, 2015-03, Vol.7 (3), p.339-356

2015

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The Human Tau Interactome: Binding to the Ribonucleoproteome, and Impaired Binding of the Proline-to-Leucine Mutant at Position 301 (P301L) to Chaperones and the Proteasome

Molecular & cellular proteomics, 2015-11, Vol.14 (11), p.3000-3014

2015

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Aggregation of Aβ40/42 chains in the presence of cyclic neuropeptides investigated by molecular dynamics simulations

PLoS computational biology, 2021-03, Vol.17 (3), p.e1008771

2021

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The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis

PloS one, 2015-08, Vol.10 (8), p.e0133741-e0133741

2015

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The human brain somatostatin interactome: SST binds selectively to P-type family ATPases

PloS one, 2019-05, Vol.14 (5), p.e0217392-e0217392

2019

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The cellular prion protein interacts with and promotes the activity of Na,K-ATPases

PloS one, 2021-11, Vol.16 (11), p.e0258682-e0258682

2021

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Cardiac glycoside-mediated turnover of Na, K-ATPases as a rational approach to reducing cell surface levels of the cellular prion protein

PloS one, 2022-07, Vol.17 (7), p.e0270915-e0270915

2022

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Identification of a Cardiac Glycoside Exhibiting Favorable Brain Bioavailability and Potency for Reducing Levels of the Cellular Prion Protein

International journal of molecular sciences, 2022-11, Vol.23 (23), p.14823

2022

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Evolutionary descent of prion genes from the ZIP family of metal ion transporters

PloS one, 2009-09, Vol.4 (9), p.e7208-e7208

2009

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CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome

PloS one, 2014-12, Vol.9 (12), p.e114594

2014

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The MEF2A transcription factor interactome in cardiomyocytes

Cell death & disease, 2023-04, Vol.14 (4), p.240-240, Article 240

2023

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Co-immunoprecipitations revisited: an update on experimental concepts and their implementation for sensitive interactome investigations of endogenous proteins

Analytical and bioanalytical chemistry, 2007-09, Vol.389 (2), p.461-473

2007

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Prion Protein Deficiency Causes Diverse Proteome Shifts in Cell Models That Escape Detection in Brain Tissue

PloS one, 2016-06, Vol.11 (6), p.e0156779-e0156779

2016

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Interactome analyses identify ties of PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulum-derived chaperones

PLoS pathogens, 2009-10, Vol.5 (10), p.e1000608-e1000608

2009

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Prion-like propagation of β-amyloid aggregates in the absence of APP overexpression

Acta neuropathologica communications, 2018-04, Vol.6 (1), p.26-26, Article 26

2018

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Application of CRISPR genetic screens to investigate neurological diseases

Molecular neurodegeneration, 2019-11, Vol.14 (1), p.41-41, Article 41

2019

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The IDIP framework for assessing protein function and its application to the prion protein

A single protective polymorphism in the prion protein blocks cross‐species prion replication in cultured cells

Loss of prion protein control of glucose metabolism promotes neurodegeneration in model of prion diseases

Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers

Proteome-wide identification of mycobacterial pupylation targets

The CNS glycoprotein Shadoo has PrPC-like protective properties and displays reduced levels in prion infections

Endoproteolytic processing of the mammalian prion glycoprotein family

Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration

Drug Repositioning for Alzheimer's Disease Based on Systematic 'omics' Data Mining

Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation

The Human Tau Interactome: Binding to the Ribonucleoproteome, and Impaired Binding of the Proline-to-Leucine Mutant at Position 301 (P301L) to Chaperones and the Proteasome

Aggregation of Aβ40/42 chains in the presence of cyclic neuropeptides investigated by molecular dynamics simulations

The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis

The human brain somatostatin interactome: SST binds selectively to P-type family ATPases

The cellular prion protein interacts with and promotes the activity of Na,K-ATPases

Cardiac glycoside-mediated turnover of Na, K-ATPases as a rational approach to reducing cell surface levels of the cellular prion protein

Identification of a Cardiac Glycoside Exhibiting Favorable Brain Bioavailability and Potency for Reducing Levels of the Cellular Prion Protein

Evolutionary descent of prion genes from the ZIP family of metal ion transporters

CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome

The MEF2A transcription factor interactome in cardiomyocytes

Co-immunoprecipitations revisited: an update on experimental concepts and their implementation for sensitive interactome investigations of endogenous proteins

Prion Protein Deficiency Causes Diverse Proteome Shifts in Cell Models That Escape Detection in Brain Tissue

Interactome analyses identify ties of PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulum-derived chaperones

Prion-like propagation of β-amyloid aggregates in the absence of APP overexpression

Application of CRISPR genetic screens to investigate neurological diseases

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