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Resistance to second-generation androgen receptor antagonists in prostate cancer

Nature reviews. Urology, 2021-04, Vol.18 (4), p.209-226

2021

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Precision Oncology Medicine: The Clinical Relevance of Patient-Specific Biomarkers Used to Optimize Cancer Treatment

Journal of clinical pharmacology, 2016-12, Vol.56 (12), p.1484-1499

2016

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Reviewing the role of healthy volunteer studies in drug development

Journal of translational medicine, 2018-12, Vol.16 (1), p.336-15, Article 336

2018

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Germline Genetics of Prostate Cancer: Prevalence of Risk Variants and Clinical Implications for Disease Management

Cancers, 2021-04, Vol.13 (9), p.2154

2021

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Pharmacokinetics and pharmacogenomics of ribociclib in black patients with metastatic breast cancer the LEANORA study

NPJ breast cancer, 2024-09, Vol.10 (1), p.84-9, Article 84

2024

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A Metabolomics Approach for Predicting OATP1B-Type Transporter-Mediated Drug–Drug Interaction Liabilities

Pharmaceutics, 2022-09, Vol.14 (9), p.1933

2022

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Whole-exome sequencing reveals germline-mutated small cell lung cancer subtype with favorable response to DNA repair-targeted therapies

Science translational medicine, 2021-01, Vol.13 (578)

2021

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Insulin potentiation therapy for cancer?

The lancet oncology, 2019-02, Vol.20 (2), p.191-192

2019

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In Silico Re‐Optimization of Atezolizumab Dosing Using Population Pharmacokinetic Simulation and Exposure–Response Simulation

Journal of clinical pharmacology, 2023-06, Vol.63 (6), p.672-680

2023

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Antitumor Activity of NLG207 (Formerly CRLX101) in Combination with Enzalutamide in Preclinical Prostate Cancer Models

Molecular cancer therapeutics, 2021-05, Vol.20 (5), p.915-924

2021

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Combination treatment in metastatic castration-resistant prostate cancer: can we safely boost efficacy by adding radium-223?

Cancer biology & therapy, 2020-01, Vol.21 (1), p.1-3

2020

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A Single-arm Phase II Study Combining NLG207, a Nanoparticle Camptothecin, with Enzalutamide in Advanced Metastatic Castration-resistant Prostate Cancer Post-Enzalutamide

The oncologist (Dayton, Ohio), 2022-09, Vol.27 (9), p.718-e694

2022

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Examining HSD3B1 as a possible biomarker to detect prostate cancer patients who are likely to progress on ADT

Cancer biology & therapy, 2020-09, Vol.21 (9), p.782-784

2020

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Measurement of NLG207 (formerly CRLX101) nanoparticle-bound and released camptothecin in human plasma

Journal of pharmaceutical and biomedical analysis, 2020-03, Vol.181, p.113073-113073, Article 113073

2020

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Study to Compare Capsule and Liquid Formulations of Enzalutamide After Single‐Dose Administration Under Fasting Conditions in Prostate Cancer

The oncologist (Dayton, Ohio), 2021-09, Vol.26 (9), p.729-e1493

2021

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Population pharmacokinetic analysis of nanoparticle-bound and free camptothecin after administration of NLG207 in adults with advanced solid tumors

Cancer chemotherapy and pharmacology, 2020-10, Vol.86 (4), p.475-486

2020

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Expanding the use of abiraterone in prostate cancer: Is earlier always better?

Cancer biology & therapy, 2018-02, Vol.19 (2), p.97-100

2018

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A population pharmacokinetic analysis of the oral CYP17 lyase and androgen receptor inhibitor seviteronel in patients with advanced/metastatic castration-resistant prostate cancer or breast cancer

Cancer chemotherapy and pharmacology, 2019-10, Vol.84 (4), p.759-770

2019

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The potential role of curcumin in prostate cancer: the importance of optimizing pharmacokinetics in clinical studies

Translational cancer research, 2016-11, Vol.5 (S6), p.S1107-S1110

2016

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Phase 2 Study of Seviteronel (INO-464) in Patients With Metastatic Castration-Resistant Prostate Cancer After Enzalutamide Treatment

Clinical genitourinary cancer, 2020-08, Vol.18 (4), p.258-267.e1

2020

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Sitagliptin elevates plasma and CSF incretin levels following oral administration to nonhuman primates: relevance for neurodegenerative disorders

GeroScience, 2024-03, Vol.46 (5), p.4397-4414

2024

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Effect of inhaled iloprost on gas exchange in inhalation injury

Burns open : an international open access journal for burn injuries, 2017-10, Vol.1 (2), p.49-53

2017

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Anti-tumor activity of NLG207 (formerly CRLX101) in combination with enzalutamide in preclinical prostate cancer models

Molecular cancer therapeutics, 2021-02, Vol.20 (5), p.915-924

2021

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Abstract B068: Treatment combinations targeting MCL-1 and BCL-xL exert synergistic anti-tumor effects in AR-V7 expressing CRPC cell lines

Cancer research (Chicago, Ill.), 2023-06, Vol.83 (11_Supplement), p.B068-B068

2023

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A Phase 2 Study of Seviteronel (INO-464) in Patients with Metastatic Castration-Resistant Prostate Cancer Post-Enzalutamide Treatment

Clinical genitourinary cancer, 2020-03, Vol.18 (4), p.258-267.e1

2020

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Resistance to second-generation androgen receptor antagonists in prostate cancer

Precision Oncology Medicine: The Clinical Relevance of Patient-Specific Biomarkers Used to Optimize Cancer Treatment

Reviewing the role of healthy volunteer studies in drug development

Germline Genetics of Prostate Cancer: Prevalence of Risk Variants and Clinical Implications for Disease Management

Pharmacokinetics and pharmacogenomics of ribociclib in black patients with metastatic breast cancer the LEANORA study

A Metabolomics Approach for Predicting OATP1B-Type Transporter-Mediated Drug–Drug Interaction Liabilities

Whole-exome sequencing reveals germline-mutated small cell lung cancer subtype with favorable response to DNA repair-targeted therapies

Insulin potentiation therapy for cancer?

In Silico Re‐Optimization of Atezolizumab Dosing Using Population Pharmacokinetic Simulation and Exposure–Response Simulation

Antitumor Activity of NLG207 (Formerly CRLX101) in Combination with Enzalutamide in Preclinical Prostate Cancer Models

Combination treatment in metastatic castration-resistant prostate cancer: can we safely boost efficacy by adding radium-223?

A Single-arm Phase II Study Combining NLG207, a Nanoparticle Camptothecin, with Enzalutamide in Advanced Metastatic Castration-resistant Prostate Cancer Post-Enzalutamide

Examining HSD3B1 as a possible biomarker to detect prostate cancer patients who are likely to progress on ADT

Measurement of NLG207 (formerly CRLX101) nanoparticle-bound and released camptothecin in human plasma

Study to Compare Capsule and Liquid Formulations of Enzalutamide After Single‐Dose Administration Under Fasting Conditions in Prostate Cancer

Population pharmacokinetic analysis of nanoparticle-bound and free camptothecin after administration of NLG207 in adults with advanced solid tumors

Expanding the use of abiraterone in prostate cancer: Is earlier always better?

A population pharmacokinetic analysis of the oral CYP17 lyase and androgen receptor inhibitor seviteronel in patients with advanced/metastatic castration-resistant prostate cancer or breast cancer

The potential role of curcumin in prostate cancer: the importance of optimizing pharmacokinetics in clinical studies

Phase 2 Study of Seviteronel (INO-464) in Patients With Metastatic Castration-Resistant Prostate Cancer After Enzalutamide Treatment

Sitagliptin elevates plasma and CSF incretin levels following oral administration to nonhuman primates: relevance for neurodegenerative disorders

Effect of inhaled iloprost on gas exchange in inhalation injury

Anti-tumor activity of NLG207 (formerly CRLX101) in combination with enzalutamide in preclinical prostate cancer models

Abstract B068: Treatment combinations targeting MCL-1 and BCL-xL exert synergistic anti-tumor effects in AR-V7 expressing CRPC cell lines

A Phase 2 Study of Seviteronel (INO-464) in Patients with Metastatic Castration-Resistant Prostate Cancer Post-Enzalutamide Treatment

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