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In Vitro Approaches to Predicting Drug Interactions In Vivo

Biochemical pharmacology, 1998, Vol.55 (2), p.113-122

1998

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Innovation in Pharmacovigilance: Use of Artificial Intelligence in Adverse Event Case Processing

Clinical pharmacology and therapeutics, 2019-04, Vol.105 (4), p.954-961

2019

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A Risk Evaluation and Mitigation Strategy (REMS) to manage the risks of overdose, abuse, addiction, and diversion with rapid-onset opioids

The journal of pain, 2010-04, Vol.11 (4), p.S23-S23

2010

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Cerebrospinal fluid concentrations of corticotropin-releasing hormone, vasopressin, and somatostatin in depressed patients and healthy controls: Response to amitriptyline treatment

Depression and anxiety, 1998, Vol.8 (2), p.71-79

1998

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Age-associated changes of pituitary-adrenocortical hormone regulation in humans: Importance of gender

Neurobiology of aging, 1994-03, Vol.15 (2), p.227-231

1994

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Relative Contribution of CYP3A to Amitriptyline Clearance in Humans: In Vitro and In Vivo Studies

Journal of clinical pharmacology, 2001-10, Vol.41 (10), p.1043-1054

2001

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Multiple Human Cytochromes Contribute to Biotransformation of Dextromethorphan In-vitro: Role of CYP2C9, CYP2C19, CYP2D6, and CYP3A

Journal of pharmacy and pharmacology, 1998-09, Vol.50 (9), p.997-1004

1998

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N-demethylation of amitriptyline in vitro: role of cytochrome P-450 3A (CYP3A) isoforms and effect of metabolic inhibitors

The Journal of pharmacology and experimental therapeutics, 1995-11, Vol.275 (2), p.592

1995

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Impact of cytochrome P-450 inhibition by cimetidine and induction by carbamazepine on the kinetics of hypericin and pseudohypericin in healthy volunteers

European journal of clinical pharmacology, 2004-11, Vol.60 (9), p.617-622

2004

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Evaluating the postmarketing experience of risperidone use during pregnancy : Pregnancy and neonatal outcomes

Drug safety, 2007-01, Vol.30 (3), p.247-264

2007

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Cytochrome P-450 enzymes and FMO3 contribute to the disposition of the antipsychotic drug perazine in vitro

Psychopharmacology, 2000-09, Vol.151 (4), p.312-320

2000

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Clozapine in Tourette's syndrome

Journal of clinical psychopharmacology, 1998-02, Vol.18 (1), p.88-89

1998

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Metabolism of Dextromethorphan in vitro: Involvement of Cytochromes P450 2D6 AND 3A3/4, with a Possible Role of 2E1

Biopharmaceutics & drug disposition, 1997-04, Vol.18 (3), p.227-240

1997

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Decreased plasma levels of amitriptyline and its metabolites on comedication with an extract from St. John's Wort (Hypericum perforatum)

Journal of clinical psychopharmacology, 2002-02, Vol.22 (1), p.46-54

2002

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Inhibition of Human Cytochrome P450-3A Isoforms by Fluoxetine and Norfluoxetine: In Vitro and In Vivo Studies

Journal of clinical pharmacology, 1996-09, Vol.36 (9), p.792-798

1996

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Endurance Training and its Effect upon the Activity of the GH-IGFs System in the Elderly

International journal of sports medicine, 1998-05, Vol.19 (4), p.250-254

1998

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Relationship of in vitro data on drug metabolism to in vivo pharmacokinetics and drug interactions : Implications for diazepam disposition in humans

Journal of clinical psychopharmacology, 1996-08, Vol.16 (4), p.267-272

1996

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The clinician and drug interactions : An update

Journal of clinical psychopharmacology, 1996-06, Vol.16 (3), p.197-201

1996

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Pituitary-adrenal-system regulation and psychopathology during amitriptyline treatment in elderly depressed patients and normal comparison subjects

The American journal of psychiatry, 1996-01, Vol.153 (1), p.93-99

1996

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Testosterone, gonadotropin, and cortisol secretion in male patients with major depression

Psychosomatic medicine, 1999-05, Vol.61 (3), p.292

1999

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Diurnal activity and pulsatility of the hypothalamus-pituitary-adrenal system in male depressed patients and healthy controls

The journal of clinical endocrinology and metabolism, 1997, Vol.82 (1), p.234-238

1997

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With aging in humans the activity of the hypothalamus-pituitary-adrenal system increases and its diurnal amplitude flattens

Life sciences (1973), 1997-10, Vol.61 (22), p.2239-2246

1997

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Midazolam Hydroxylation by Human Liver Microsomes In Vitro: Inhibition by Fluoxetine, Norfluoxetine, and by Azole Antifungal Agents

Journal of clinical pharmacology, 1996-09, Vol.36 (9), p.783-791

1996

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Five Distinct Human Cytochromes Mediate Amitriptyline N-Demethylation In Vitro: Dominance of CYP 2C19 and 3A4

Journal of clinical pharmacology, 1998-02, Vol.38 (2), p.112-121

1998

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Combined dexamethasone/corticotropin-releasing hormone test in acute and remitted manic patients, in acute depression, and in normal controls: I

Biological psychiatry (1969), 1995-12, Vol.38 (12), p.797-802

1995

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In Vitro Approaches to Predicting Drug Interactions In Vivo

Innovation in Pharmacovigilance: Use of Artificial Intelligence in Adverse Event Case Processing

A Risk Evaluation and Mitigation Strategy (REMS) to manage the risks of overdose, abuse, addiction, and diversion with rapid-onset opioids

Cerebrospinal fluid concentrations of corticotropin-releasing hormone, vasopressin, and somatostatin in depressed patients and healthy controls: Response to amitriptyline treatment

Age-associated changes of pituitary-adrenocortical hormone regulation in humans: Importance of gender

Relative Contribution of CYP3A to Amitriptyline Clearance in Humans: In Vitro and In Vivo Studies

Multiple Human Cytochromes Contribute to Biotransformation of Dextromethorphan In-vitro: Role of CYP2C9, CYP2C19, CYP2D6, and CYP3A

N-demethylation of amitriptyline in vitro: role of cytochrome P-450 3A (CYP3A) isoforms and effect of metabolic inhibitors

Impact of cytochrome P-450 inhibition by cimetidine and induction by carbamazepine on the kinetics of hypericin and pseudohypericin in healthy volunteers

Evaluating the postmarketing experience of risperidone use during pregnancy : Pregnancy and neonatal outcomes

Cytochrome P-450 enzymes and FMO3 contribute to the disposition of the antipsychotic drug perazine in vitro

Clozapine in Tourette's syndrome

Metabolism of Dextromethorphan in vitro: Involvement of Cytochromes P450 2D6 AND 3A3/4, with a Possible Role of 2E1

Decreased plasma levels of amitriptyline and its metabolites on comedication with an extract from St. John's Wort (Hypericum perforatum)

Inhibition of Human Cytochrome P450-3A Isoforms by Fluoxetine and Norfluoxetine: In Vitro and In Vivo Studies

Endurance Training and its Effect upon the Activity of the GH-IGFs System in the Elderly

Relationship of in vitro data on drug metabolism to in vivo pharmacokinetics and drug interactions : Implications for diazepam disposition in humans

The clinician and drug interactions : An update

Pituitary-adrenal-system regulation and psychopathology during amitriptyline treatment in elderly depressed patients and normal comparison subjects

Testosterone, gonadotropin, and cortisol secretion in male patients with major depression

Diurnal activity and pulsatility of the hypothalamus-pituitary-adrenal system in male depressed patients and healthy controls

With aging in humans the activity of the hypothalamus-pituitary-adrenal system increases and its diurnal amplitude flattens

Midazolam Hydroxylation by Human Liver Microsomes In Vitro: Inhibition by Fluoxetine, Norfluoxetine, and by Azole Antifungal Agents

Five Distinct Human Cytochromes Mediate Amitriptyline N-Demethylation In Vitro: Dominance of CYP 2C19 and 3A4

Combined dexamethasone/corticotropin-releasing hormone test in acute and remitted manic patients, in acute depression, and in normal controls: I

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