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Advancements in DNA vaccine vectors, non-mechanical delivery methods, and molecular adjuvants to increase immunogenicity

Human vaccines & immunotherapeutics, 2017-12, Vol.13 (12), p.2837-2848

2017

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A DNA vaccine for Crimean-Congo hemorrhagic fever protects against disease and death in two lethal mouse models

PLoS neglected tropical diseases, 2017-09, Vol.11 (9), p.e0005908-e0005908

2017

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Endothelial cell permeability during hantavirus infection involves factor XII-dependent increased activation of the kallikrein-kinin system

PLoS pathogens, 2013-07, Vol.9 (7), p.e1003470-e1003470

2013

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Vaccines against Ebola virus and Marburg virus: recent advances and promising candidates

Human vaccines & immunotherapeutics, 2019-10, Vol.15 (10), p.2359-2377

2019

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A Brief History of Bunyaviral Family Hantaviridae

Diseases, 2023-02, Vol.11 (1), p.38

2023

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IFITM-2 and IFITM-3 but Not IFITM-1 Restrict Rift Valley Fever Virus

Journal of Virology, 2013-08, Vol.87 (15), p.8451-8464

2013

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Immune-Mediated Systemic Vasculitis as the Proposed Cause of Sudden-Onset Sensorineural Hearing Loss following Lassa Virus Exposure in Cynomolgus Macaques

mBio, 2018-10, Vol.9 (5)

2018

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Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses

Cell host & microbe, 2007-12, Vol.2 (6), p.404-416

2007

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Pending Reorganization of Hantaviridae to Include Only Completely Sequenced Viruses: A Call to Action

Viruses, 2023-02, Vol.15 (3), p.660

2023

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HSP90 is part of a protein complex with the L polymerase of Rift Valley fever phlebovirus and prevents its degradation by the proteasome during the viral genome replication/transcription stage

Frontiers in cellular and infection microbiology, 2024, Vol.14, p.1331755-1331755

2024

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Hantaan Virus Nucleocapsid Protein Binds to Importin α Proteins and Inhibits Tumor Necrosis Factor Alpha-Induced Activation of Nuclear Factor Kappa B

Journal of Virology, 2009-02, Vol.83 (3), p.1271-1279

2009

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Crimean–Congo hemorrhagic fever virus utilizes a clathrin- and early endosome-dependent entry pathway

Virology (New York, N.Y.), 2013-09, Vol.444 (1), p.45-54

2013

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GP38-targeting monoclonal antibodies protect adult mice against lethal Crimean-Congo hemorrhagic fever virus infection

Science advances, 2019-07, Vol.5 (7), p.eaaw9535-eaaw9535

2019

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A CCHFV DNA vaccine protects against heterologous challenge and establishes GP38 as immunorelevant in mice

npj vaccines, 2021-03, Vol.6 (1), p.31-31, Article 31

2021

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A Multiagent Alphavirus DNA Vaccine Delivered by Intramuscular Electroporation Elicits Robust and Durable Virus-Specific Immune Responses in Mice and Rabbits and Completely Protects Mice against Lethal Venezuelan, Western, and Eastern Equine Encephalitis Virus Aerosol Challenges

Journal of Immunology Research, 2018-01, Vol.2018 (2018), p.1-15

2018

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Thottapalayam virus, a prototype shrewborne hantavirus

Emerging infectious diseases, 2007-07, Vol.13 (7), p.980-985

2007

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A DNA vaccine delivered by dermal electroporation fully protects cynomolgus macaques against Lassa fever

Human vaccines & immunotherapeutics, 2017-12, Vol.13 (12), p.2902-2911

2017

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Multivalent DNA Vaccines as A Strategy to Combat Multiple Concurrent Epidemics: Mosquito-Borne and Hemorrhagic Fever Viruses

Viruses, 2021-02, Vol.13 (3), p.382

2021

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Nanoplasmid Vectors Co-expressing Innate Immune Agonists Enhance DNA Vaccines for Venezuelan Equine Encephalitis Virus and Ebola Virus

Molecular therapy. Methods & clinical development, 2020-06, Vol.17 (C), p.810-821

2020

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Nuclear Relocalization of Polyadenylate Binding Protein during Rift Valley Fever Virus Infection Involves Expression of the NSs Gene

Journal of Virology, 2013-11, Vol.87 (21), p.11659-11669

2013

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Immunogenicity of a protective intradermal DNA vaccine against lassa virus in cynomolgus macaques

Human vaccines & immunotherapeutics, 2019-09, Vol.15 (9), p.2066-2074

2019

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Human Polyclonal Antibodies Produced through DNA Vaccination of Transchromosomal Cattle Provide Mice with Post-Exposure Protection against Lethal Zaire and Sudan Ebolaviruses

PloS one, 2015-09, Vol.10 (9), p.e0137786-e0137786

2015

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A DNA Vaccine for Venezuelan Equine Encephalitis Virus Delivered by Intramuscular Electroporation Elicits High Levels of Neutralizing Antibodies in Multiple Animal Models and Provides Protective Immunity to Mice and Nonhuman Primates

Clinical and Vaccine Immunology, 2011-05, Vol.18 (5), p.707-716

2011

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Junin Virus Activates p38 MAPK and HSP27 Upon Entry

Frontiers in cellular and infection microbiology, 2022-04, Vol.12, p.798978-798978

2022

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Identification of a Novel C-Terminal Cleavage of Crimean-Congo Hemorrhagic Fever Virus PreGN That Leads to Generation of an NSM Protein

Journal of Virology, 2007-06, Vol.81 (12), p.6632-6642

2007

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Advancements in DNA vaccine vectors, non-mechanical delivery methods, and molecular adjuvants to increase immunogenicity

A DNA vaccine for Crimean-Congo hemorrhagic fever protects against disease and death in two lethal mouse models

Endothelial cell permeability during hantavirus infection involves factor XII-dependent increased activation of the kallikrein-kinin system

Vaccines against Ebola virus and Marburg virus: recent advances and promising candidates

A Brief History of Bunyaviral Family Hantaviridae

IFITM-2 and IFITM-3 but Not IFITM-1 Restrict Rift Valley Fever Virus

Immune-Mediated Systemic Vasculitis as the Proposed Cause of Sudden-Onset Sensorineural Hearing Loss following Lassa Virus Exposure in Cynomolgus Macaques

Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses

Pending Reorganization of Hantaviridae to Include Only Completely Sequenced Viruses: A Call to Action

HSP90 is part of a protein complex with the L polymerase of Rift Valley fever phlebovirus and prevents its degradation by the proteasome during the viral genome replication/transcription stage

Hantaan Virus Nucleocapsid Protein Binds to Importin α Proteins and Inhibits Tumor Necrosis Factor Alpha-Induced Activation of Nuclear Factor Kappa B

Crimean–Congo hemorrhagic fever virus utilizes a clathrin- and early endosome-dependent entry pathway

GP38-targeting monoclonal antibodies protect adult mice against lethal Crimean-Congo hemorrhagic fever virus infection

A CCHFV DNA vaccine protects against heterologous challenge and establishes GP38 as immunorelevant in mice

A Multiagent Alphavirus DNA Vaccine Delivered by Intramuscular Electroporation Elicits Robust and Durable Virus-Specific Immune Responses in Mice and Rabbits and Completely Protects Mice against Lethal Venezuelan, Western, and Eastern Equine Encephalitis Virus Aerosol Challenges

Thottapalayam virus, a prototype shrewborne hantavirus

A DNA vaccine delivered by dermal electroporation fully protects cynomolgus macaques against Lassa fever

Multivalent DNA Vaccines as A Strategy to Combat Multiple Concurrent Epidemics: Mosquito-Borne and Hemorrhagic Fever Viruses

Nanoplasmid Vectors Co-expressing Innate Immune Agonists Enhance DNA Vaccines for Venezuelan Equine Encephalitis Virus and Ebola Virus

Nuclear Relocalization of Polyadenylate Binding Protein during Rift Valley Fever Virus Infection Involves Expression of the NSs Gene

Immunogenicity of a protective intradermal DNA vaccine against lassa virus in cynomolgus macaques

Human Polyclonal Antibodies Produced through DNA Vaccination of Transchromosomal Cattle Provide Mice with Post-Exposure Protection against Lethal Zaire and Sudan Ebolaviruses

A DNA Vaccine for Venezuelan Equine Encephalitis Virus Delivered by Intramuscular Electroporation Elicits High Levels of Neutralizing Antibodies in Multiple Animal Models and Provides Protective Immunity to Mice and Nonhuman Primates

Junin Virus Activates p38 MAPK and HSP27 Upon Entry

Identification of a Novel C-Terminal Cleavage of Crimean-Congo Hemorrhagic Fever Virus PreGN That Leads to Generation of an NSM Protein

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