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The potential and promise of IL-15 in immuno-oncogenic therapies

Immunology letters, 2017-10, Vol.190, p.159-168

2017

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IL-15 is a component of the inflammatory milieu in the tumor microenvironment promoting antitumor responses

Proceedings of the National Academy of Sciences - PNAS, 2019-01, Vol.116 (2), p.599-608

2019

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Regulation of inflammatory responses by IL-17F

The Journal of experimental medicine, 2008-05, Vol.205 (5), p.1063-1075

2008

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Nfil3-independent lineage maintenance and antiviral response of natural killer cells

The Journal of experimental medicine, 2013-12, Vol.210 (13), p.2981-2990

2013

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Transcription of Il17 and Il17f Is Controlled by Conserved Noncoding Sequence 2

Immunity (Cambridge, Mass.), 2012-01, Vol.36 (1), p.23-31

2012

Volltextzugriff (PDF)

Transcriptional regulation of IL-15 expression during hematopoiesis

The Journal of immunology (1950), 2013-09, Vol.191 (6), p.3017-3024

2013

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Thymic Epithelial Cell-Derived IL-15 and IL-15 Receptor α Chain Foster Local Environment for Type 1 Innate Like T Cell Development

Frontiers in immunology, 2021-03, Vol.12, p.623280-623280

2021

Volltextzugriff (PDF)

Dendritic Cells Support the In Vivo Development and Maintenance of NK Cells via IL-15 Trans-Presentation

The Journal of immunology (1950), 2009-10, Vol.183 (8), p.4948-4956

2009

Volltextzugriff (PDF)

Inflammatory Signals Regulate IL-15 in Response to Lymphodepletion

The Journal of immunology (1950), 2016-06, Vol.196 (11), p.4544-4552

2016

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Soluble interleukin-15 complexes are generated in vivo by type I interferon dependent and independent pathways

PloS one, 2015-03, Vol.10 (3), p.e0120274-e0120274

2015

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Absence of Grail promotes CD8 + T cell anti-tumour activity

Nature communications, 2017-08, Vol.8 (1), p.239-14, Article 239

2017

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Neutrophils Regulate Humoral Autoimmunity by Restricting Interferon-γ Production via the Generation of Reactive Oxygen Species

Cell reports (Cambridge), 2015-08, Vol.12 (7), p.1120-1132

2015

Volltextzugriff (PDF)

Sublingual vaccination induces mucosal and systemic adaptive immunity for protection against lung tumor challenge

PloS one, 2014-03, Vol.9 (3), p.e90001-e90001

2014

Volltextzugriff (PDF)

Thymic and peripheral microenvironments differentially mediate development and maturation of iNKT cells by IL-15 transpresentation

Blood, 2010-10, Vol.116 (14), p.2494-2503

2010

Volltextzugriff (PDF)

Optimisation of a primary human CAR-NK cell manufacturing pipeline

Clinical & translational immunology, 2024-01, Vol.13 (5), p.e1507-e1507

2024

Volltextzugriff (PDF)

Inhibition of urothelial carcinoma through targeted type I interferon-mediated immune activation

Oncoimmunology, 2019-05, Vol.8 (5), p.e1577125-e1577125

2019

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Distinct Cell Types Control Lymphoid Subset Development by Means of IL-15 and IL-15 Receptor α Expression

Proceedings of the National Academy of Sciences - PNAS, 2004-04, Vol.101 (15), p.5616-5621

2004

Volltextzugriff (PDF)

Cytokine control of memory T-cell development and survival

Nature reviews. Immunology, 2003-04, Vol.3 (4), p.269-279

2003

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Persistent antigen at vaccination sites induces tumor-specific CD8⁺ T cell sequestration, dysfunction and deletion

Nature medicine, 2013-04, Vol.19 (4), p.465-472

2013

Volltextzugriff (PDF)

Trans-presentation: A novel mechanism regulating IL-15 delivery and responses

Immunology letters, 2010-01, Vol.127 (2), p.85-92

2010

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Combined IL-15/IL-15Rα Immunotherapy Maximizes IL-15 Activity In Vivo

Journal of Immunology, 2006-11, Vol.177 (9), p.6072-6080

2006

Volltextzugriff (PDF)

Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell Programs

Immunity (Cambridge, Mass.), 2008-07, Vol.29 (1), p.44-56

2008

Volltextzugriff (PDF)

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ

Immunity (Cambridge, Mass.), 2008-01, Vol.28 (1), p.29-39

2008

Volltextzugriff (PDF)

Regulating the immune system via IL-15 transpresentation

Cytokine (Philadelphia, Pa.), 2012-09, Vol.59 (3), p.479-490

2012

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NKTR-255 is a polymer-conjugated IL-15 with unique mechanisms of action on T and natural killer cells

The Journal of clinical investigation, 2021-10, Vol.131 (19), p.1-14

2021

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The potential and promise of IL-15 in immuno-oncogenic therapies

IL-15 is a component of the inflammatory milieu in the tumor microenvironment promoting antitumor responses

Regulation of inflammatory responses by IL-17F

Nfil3-independent lineage maintenance and antiviral response of natural killer cells

Transcription of Il17 and Il17f Is Controlled by Conserved Noncoding Sequence 2

Transcriptional regulation of IL-15 expression during hematopoiesis

Thymic Epithelial Cell-Derived IL-15 and IL-15 Receptor α Chain Foster Local Environment for Type 1 Innate Like T Cell Development

Dendritic Cells Support the In Vivo Development and Maintenance of NK Cells via IL-15 Trans-Presentation

Inflammatory Signals Regulate IL-15 in Response to Lymphodepletion

Soluble interleukin-15 complexes are generated in vivo by type I interferon dependent and independent pathways

Absence of Grail promotes CD8 + T cell anti-tumour activity

Neutrophils Regulate Humoral Autoimmunity by Restricting Interferon-γ Production via the Generation of Reactive Oxygen Species

Sublingual vaccination induces mucosal and systemic adaptive immunity for protection against lung tumor challenge

Thymic and peripheral microenvironments differentially mediate development and maturation of iNKT cells by IL-15 transpresentation

Optimisation of a primary human CAR-NK cell manufacturing pipeline

Inhibition of urothelial carcinoma through targeted type I interferon-mediated immune activation

Distinct Cell Types Control Lymphoid Subset Development by Means of IL-15 and IL-15 Receptor α Expression

Cytokine control of memory T-cell development and survival

Persistent antigen at vaccination sites induces tumor-specific CD8⁺ T cell sequestration, dysfunction and deletion

Trans-presentation: A novel mechanism regulating IL-15 delivery and responses

Combined IL-15/IL-15Rα Immunotherapy Maximizes IL-15 Activity In Vivo

Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell Programs

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ

Regulating the immune system via IL-15 transpresentation

NKTR-255 is a polymer-conjugated IL-15 with unique mechanisms of action on T and natural killer cells

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