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Targeted tumor therapy with the TGF-beta 2 antisense compound AP 12009

Cytokine & growth factor reviews, 2006-02, Vol.17 (1-2), p.129-139

2006

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Regional and temporal expression of sodium channel messenger RNAs in the rat brain during development

Experimental brain research, 1991-01, Vol.86 (3), p.562-567

1991

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Block of c-Fos and JunB Expression by Antisense Oligonucleotides Inhibits Light-induced-Phase Shifts of the Mammalian Circadian Clock

The European journal of neuroscience, 1995-03, Vol.7 (3), p.388-393

1995

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The role of transforming growth factor-β in carcinogenesis

Nature reviews. Cancer, 2005-12, Vol.5 (12), p.995-995

2005

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Inhibition of immunosuppressive effects of melanoma‐inhibiting activity (MIA) by antisense techniques

International journal of cancer, 2005-01, Vol.113 (1), p.88-92

2005

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Clearance kinetics, biodistribution, and organ saturability of phosphorothioate oligodeoxynucleotides in mice

The American journal of pathology, 1996-08, Vol.149 (2), p.717-725

1996

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The role of Jun transcription factor expression and phosphorylation in neuronal differentiation, neuronal cell death, and plastic adaptations in vivo

Cellular and molecular neurobiology, 1994-10, Vol.14 (5), p.487-506

1994

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Sequence-specific impairment of learning by c-jun antisense oligonucleotides

Neuroreport, 1994-07, Vol.5 (12), p.1501-1504

1994

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Developmental expression of the transcription factor zif268 in rat brain

Neuroscience letters, 1994-01, Vol.165 (1), p.171-174

1994

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Changes in the expression of synapsin I and II messenger RNA during postnatal rat brain development

Experimental brain research, 1996-03, Vol.108 (3), p.441-449

1996

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Design and application of antisense oligonucleotides in cell culture, in vivo, and as therapeutic agents

Cellular and molecular neurobiology, 1994-10, Vol.14 (5), p.557-568

1994

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Inhibition of Memory Consolidation After Active Avoidance Conditioning by Antisense Intervention with Ependymin Gene Expression

Journal of neurochemistry, 1995-10, Vol.65 (4), p.1465-1471

1995

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bFGF induces its own gene expression in astrocytic and hippocampal cell cultures

Neuroreport, 1992-12, Vol.3 (12), p.1077-1080

1992

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Changes of synapsin I messenger RNA expression during rat brain development

Experimental brain research, 1994-05, Vol.99 (1), p.17-24

1994

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Differential expression of c-jun, junB, and junD in rat hippocampal slices

Neuroreport, 1994-12, Vol.6 (1), p.101-104

1994

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Antisense bFGF oligodeoxynucleotides inhibit DNA synthesis of rat astrocytes

Neuroreport, 1992-01, Vol.3 (1), p.43-46

1992

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TGF-beta2 suppression by the antisense oligonucleotide AP 12009 as therapy for high-grade glioma: safety and efficacy results of phase I/II clinical studies

Aktuelle Neurologie, 2004, Vol.31 (S 1)

2004

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Intracerebral and intrathecal infusion of the TGF-beta 2-specific antisense phosphorothioate oligonucleotide AP 12009 in rabbits and primates: toxicology and safety

Oligonucleotides, 2005, Vol.15 (2), p.94-104

2005

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Transforming Growth Factor-β-Mediated Regulation of Human Peripheral Blood Mononuclear Cell Proliferation as Detected with Phosphorothioate Antisense Oligodeoxynucleotides

Cellular immunology, 1995-10, Vol.165 (1), p.125-133

1995

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38. Specific inhibition of different jun genes either inhibits or stimulates cell differentiation

Biomedicine & pharmacotherapy, 1992, Vol.46 (5), p.257-257

1992

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30. Proto-oneogene jun-D acts as a functional tumor suppressor gene in fibroblasts and mammary carcinoma cells

Biomedicine & pharmacotherapy, 1992, Vol.46 (5), p.253-253

1992

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Effects of transforming growth factor- beta sub(1) on collagen synthesis, integrin expression, adhesion and invasion of glioma cells

Journal of neuropathology and experimental neurology, 1995-01, Vol.54 (2), p.236-244

1995

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Neuronal plasticity depending on a glycoprotein synthesized in goldfish leptomeninx

Progress in brain research, 1992, Vol.91, p.7-12

1992

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Ca2+/calmodulin protein kinase and protein kinase C expression during development of rat hippocampus

Developmental neuroscience, 1993, Vol.15 (6), p.410-416

1993

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55. Suppression of growth factor gene expression with antisense DNA. A novel approach to tumor growth modulation

Biomedicine & pharmacotherapy, 1992, Vol.46 (5), p.265-265

1992

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Targeted tumor therapy with the TGF-beta 2 antisense compound AP 12009

Regional and temporal expression of sodium channel messenger RNAs in the rat brain during development

Block of c-Fos and JunB Expression by Antisense Oligonucleotides Inhibits Light-induced-Phase Shifts of the Mammalian Circadian Clock

The role of transforming growth factor-β in carcinogenesis

Inhibition of immunosuppressive effects of melanoma‐inhibiting activity (MIA) by antisense techniques

Clearance kinetics, biodistribution, and organ saturability of phosphorothioate oligodeoxynucleotides in mice

The role of Jun transcription factor expression and phosphorylation in neuronal differentiation, neuronal cell death, and plastic adaptations in vivo

Sequence-specific impairment of learning by c-jun antisense oligonucleotides

Developmental expression of the transcription factor zif268 in rat brain

Changes in the expression of synapsin I and II messenger RNA during postnatal rat brain development

Design and application of antisense oligonucleotides in cell culture, in vivo, and as therapeutic agents

Inhibition of Memory Consolidation After Active Avoidance Conditioning by Antisense Intervention with Ependymin Gene Expression

bFGF induces its own gene expression in astrocytic and hippocampal cell cultures

Changes of synapsin I messenger RNA expression during rat brain development

Differential expression of c-jun, junB, and junD in rat hippocampal slices

Antisense bFGF oligodeoxynucleotides inhibit DNA synthesis of rat astrocytes

TGF-beta2 suppression by the antisense oligonucleotide AP 12009 as therapy for high-grade glioma: safety and efficacy results of phase I/II clinical studies

Intracerebral and intrathecal infusion of the TGF-beta 2-specific antisense phosphorothioate oligonucleotide AP 12009 in rabbits and primates: toxicology and safety

Transforming Growth Factor-β-Mediated Regulation of Human Peripheral Blood Mononuclear Cell Proliferation as Detected with Phosphorothioate Antisense Oligodeoxynucleotides

38. Specific inhibition of different jun genes either inhibits or stimulates cell differentiation

30. Proto-oneogene jun-D acts as a functional tumor suppressor gene in fibroblasts and mammary carcinoma cells

Effects of transforming growth factor- beta sub(1) on collagen synthesis, integrin expression, adhesion and invasion of glioma cells

Neuronal plasticity depending on a glycoprotein synthesized in goldfish leptomeninx

Ca2+/calmodulin protein kinase and protein kinase C expression during development of rat hippocampus

55. Suppression of growth factor gene expression with antisense DNA. A novel approach to tumor growth modulation

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