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Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview

Advanced drug delivery reviews, 2012-12, Vol.64, p.138-153

2012

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The Mechanism-Based Inactivation of CYP3A4 by Ritonavir: What Mechanism?

International journal of molecular sciences, 2022-09, Vol.23 (17), p.9866

2022

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Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview

Advanced drug delivery reviews, 2003-01, Vol.55 (1), p.3-29

2003

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Increased oral availability and brain accumulation of the ALK inhibitor crizotinib by coadministration of the P‐glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar

International journal of cancer, 2014-03, Vol.134 (6), p.1484-1494

2014

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Organic Cation Transporter 2 Mediates Cisplatin-Induced Oto- and Nephrotoxicity and Is a Target for Protective Interventions

The American journal of pathology, 2010-03, Vol.176 (3), p.1169-1180

2010

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The impact of Organic Anion-Transporting Polypeptides (OATPs) on disposition and toxicity of antitumor drugs; insights from knockout and humanized mice

Drug resistance updates, 2016-07, Vol.27, p.72-88

2016

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Brain and Testis Accumulation of Regorafenib is Restricted by Breast Cancer Resistance Protein (BCRP/ABCG2) and P-glycoprotein (P-GP/ABCB1)

Pharmaceutical research, 2015-07, Vol.32 (7), p.2205-2216

2015

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Breast cancer resistance protein (BCRP/ABCG2) and P-glycoprotein (P-gp/ABCB1) transport afatinib and restrict its oral availability and brain accumulation

Pharmacological research, 2017-06, Vol.120, p.43-50

2017

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Brain accumulation of the EML4-ALK inhibitor ceritinib is restricted by P-glycoprotein (P-GP/ABCB1) and breast cancer resistance protein (BCRP/ABCG2)

Pharmacological research, 2015-12, Vol.102, p.200-207

2015

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Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice

Hepatology (Baltimore, Md.), 2017-11, Vol.66 (5), p.1631-1643

2017

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Breast Cancer Resistance Protein (BCRP/ABCG2) and P-glycoprotein (P-GP/ABCB1) Restrict Oral Availability and Brain Accumulation of the PARP Inhibitor Rucaparib (AG-014699)

Pharmaceutical research, 2015-01, Vol.32 (1), p.37-46

2015

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Apical ABC Transporters and Cancer Chemotherapeutic Drug Disposition

ABC Transporters and Cancer, 2015, Vol.125, p.1

2015

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Brain accumulation of osimertinib and its active metabolite AZ5104 is restricted by ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein)

Pharmacological research, 2019-08, Vol.146, p.104297, Article 104297

2019

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Influence of Human OATP1B1, OATP1B3, and OATP1A2 on the Pharmacokinetics of Methotrexate and Paclitaxel in Humanized Transgenic Mice

Clinical cancer research, 2013-02, Vol.19 (4), p.821-832

2013

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Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3)

The Journal of pharmacology and experimental therapeutics, 2004-01, Vol.308 (1), p.2

2004

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ABCB1 attenuates brain exposure to the KRASG12C inhibitor opnurasib whereas binding to mouse carboxylesterase 1c influences its plasma exposure

Biomedicine & pharmacotherapy, 2024-06, Vol.175, p.116720-116720, Article 116720

2024

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Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b

Cancer research (Chicago, Ill.), 2015-07, Vol.75 (13), p.2729-2736

2015

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Functions of OATP1A and 1B transporters in vivo: insights from mouse models

Trends in pharmacological sciences (Regular ed.), 2012-02, Vol.33 (2), p.100-108

2012

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A critical analysis of the interplay between cytochrome P450 3A and P-glycoprotein: recent insights from knockout and transgenic mice

Pharmacological reviews, 2011-06, Vol.63 (2), p.390

2011

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Ochratoxin A transport by the human breast cancer resistance protein (BCRP), multidrug resistance protein 2 (MRP2), and organic anion-transporting polypeptides 1A2, 1B1 and 2B1

Toxicology and applied pharmacology, 2017-08, Vol.329, p.18-25

2017

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Brain accumulation of tivozanib is restricted by ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein) in mice

International journal of pharmaceutics, 2020-05, Vol.581, p.119277, Article 119277

2020

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Breast cancer resistance protein and P-glycoprotein limit sorafenib brain accumulation

Molecular cancer therapeutics, 2010-02, Vol.9 (2), p.319-326

2010

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Bioanalytical liquid chromatography-tandem mass spectrometric assay for the quantification of the ALK inhibitors alectinib, brigatinib and lorlatinib in plasma and mouse tissue homogenates

Journal of pharmaceutical and biomedical analysis, 2018-11, Vol.161, p.136-143

2018

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Quantitative investigation of the role of breast cancer resistance protein (Bcrp/Abcg2) in limiting brain and testis penetration of xenobiotic compounds

Drug metabolism and disposition, 2008-06, Vol.36 (6), p.995

2008

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Metabolome Analysis Reveals Dermal Histamine Accumulation in Murine Dermatitis Provoked by Genetic Deletion of P-Glycoprotein and Breast Cancer Resistance Protein

Pharmaceutical research, 2019-11, Vol.36 (11), p.158-11, Article 158

2019

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Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview

The Mechanism-Based Inactivation of CYP3A4 by Ritonavir: What Mechanism?

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview

Increased oral availability and brain accumulation of the ALK inhibitor crizotinib by coadministration of the P‐glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar

Organic Cation Transporter 2 Mediates Cisplatin-Induced Oto- and Nephrotoxicity and Is a Target for Protective Interventions

The impact of Organic Anion-Transporting Polypeptides (OATPs) on disposition and toxicity of antitumor drugs; insights from knockout and humanized mice

Brain and Testis Accumulation of Regorafenib is Restricted by Breast Cancer Resistance Protein (BCRP/ABCG2) and P-glycoprotein (P-GP/ABCB1)

Breast cancer resistance protein (BCRP/ABCG2) and P-glycoprotein (P-gp/ABCB1) transport afatinib and restrict its oral availability and brain accumulation

Brain accumulation of the EML4-ALK inhibitor ceritinib is restricted by P-glycoprotein (P-GP/ABCB1) and breast cancer resistance protein (BCRP/ABCG2)

Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice

Breast Cancer Resistance Protein (BCRP/ABCG2) and P-glycoprotein (P-GP/ABCB1) Restrict Oral Availability and Brain Accumulation of the PARP Inhibitor Rucaparib (AG-014699)

Apical ABC Transporters and Cancer Chemotherapeutic Drug Disposition

Brain accumulation of osimertinib and its active metabolite AZ5104 is restricted by ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein)

Influence of Human OATP1B1, OATP1B3, and OATP1A2 on the Pharmacokinetics of Methotrexate and Paclitaxel in Humanized Transgenic Mice

Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3)

ABCB1 attenuates brain exposure to the KRASG12C inhibitor opnurasib whereas binding to mouse carboxylesterase 1c influences its plasma exposure

Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b

Functions of OATP1A and 1B transporters in vivo: insights from mouse models

A critical analysis of the interplay between cytochrome P450 3A and P-glycoprotein: recent insights from knockout and transgenic mice

Ochratoxin A transport by the human breast cancer resistance protein (BCRP), multidrug resistance protein 2 (MRP2), and organic anion-transporting polypeptides 1A2, 1B1 and 2B1

Brain accumulation of tivozanib is restricted by ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein) in mice

Breast cancer resistance protein and P-glycoprotein limit sorafenib brain accumulation

Bioanalytical liquid chromatography-tandem mass spectrometric assay for the quantification of the ALK inhibitors alectinib, brigatinib and lorlatinib in plasma and mouse tissue homogenates

Quantitative investigation of the role of breast cancer resistance protein (Bcrp/Abcg2) in limiting brain and testis penetration of xenobiotic compounds

Metabolome Analysis Reveals Dermal Histamine Accumulation in Murine Dermatitis Provoked by Genetic Deletion of P-Glycoprotein and Breast Cancer Resistance Protein

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