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TRPC-mediated Ca2+ signaling and control of cellular functions

Seminars in cell & developmental biology, 2019-10, Vol.94, p.28-39

2019

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A Coiled-coil Clamp Controls Both Conformation and Clustering of Stromal Interaction Molecule 1 (STIM1)

The Journal of biological chemistry, 2014-11, Vol.289 (48), p.33231-33244

2014

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An optically controlled probe identifies lipid-gating fenestrations within the TRPC3 channel

Nature chemical biology, 2018-04, Vol.14 (4), p.396-404

2018

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STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry

Nature communications, 2013-12, Vol.4 (1), p.2963, Article 2963

2013

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A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels

The Journal of biological chemistry, 2009-03, Vol.284 (13), p.8421-8426

2009

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The action of selective CRAC channel blockers is affected by the Orai pore geometry

Cell calcium (Edinburgh), 2013-02, Vol.53 (2), p.139-151

2013

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Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription

Science signaling, 2017-11, Vol.10 (507)

2017

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Dynamic Coupling of the Putative Coiled-coil Domain of ORAI1 with STIM1 Mediates ORAI1 Channel Activation

The Journal of biological chemistry, 2008-03, Vol.283 (12), p.8014-8022

2008

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Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry

Proceedings of the National Academy of Sciences - PNAS, 2011-01, Vol.108 (4), p.1337-1342

2011

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Ca2+ release-activated Ca2+ (CRAC) current, structure, and function

Cellular and molecular life sciences : CMLS, 2012, Vol.69 (24), p.4163-4176

2012

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Cholesterol modulates Orai1 channel function

Science signaling, 2016-01, Vol.9 (412), p.ra10

2016

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The STIM-Orai Pathway: The Interactions Between STIM and Orai

Advances in experimental medicine and biology, 2017, Vol.993, p.59-81

2017

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Cellular interfaces with hydrogen-bonded organic semiconductor hierarchical nanocrystals

Nature communications, 2017-07, Vol.8 (1), p.91-11, Article 91

2017

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A Ca2+ Release-activated Ca2+ (CRAC) Modulatory Domain (CMD) within STIM1 Mediates Fast Ca2+-dependent Inactivation of ORAI1 Channels

The Journal of biological chemistry, 2009-09, Vol.284 (37), p.24933-24938

2009

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Luminal STIM1 Mutants that Cause Tubular Aggregate Myopathy Promote Autophagic Processes

International journal of molecular sciences, 2020-06, Vol.21 (12), p.4410

2020

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Oxidative Stress-Induced STIM2 Cysteine Modifications Suppress Store-Operated Calcium Entry

Cell reports (Cambridge), 2020-10, Vol.33 (3), p.108292-108292, Article 108292

2020

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2-Aminoethoxydiphenyl Borate Alters Selectivity of Orai3 Channels by Increasing Their Pore Size

The Journal of biological chemistry, 2008-07, Vol.283 (29), p.20261-20267

2008

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Canonical Transient Receptor Potential (TRPC) 1 Acts as a Negative Regulator for Vanilloid TRPV6-mediated Ca2+ Influx

The Journal of biological chemistry, 2012-10, Vol.287 (42), p.35612-35620

2012

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Photo‐Chemical Stimulation of Neurons with Organic Semiconductors

Advanced science, 2023-11, Vol.10 (31), p.e2300473-e2300473

2023

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Increased Hydrophobicity at the N Terminus/Membrane Interface Impairs Gating of the Severe Combined Immunodeficiency-related ORAI1 Mutant

The Journal of biological chemistry, 2009-06, Vol.284 (23), p.15903-15915

2009

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Mrs2p forms a high conductance Mg2+ selective channel in mitochondria

Biophysical journal, 2007-12, Vol.93 (11), p.3872-3883

2007

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Plasticity in Ca²⁺ selectivity of Orai1/Orai3 heteromeric channel

Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (46), p.19623-19628

2009

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Immobilization of Recombinant Fluorescent Biosensors Permits Imaging of Extracellular Ion Signals

ACS sensors, 2021-11, Vol.6 (11), p.3994-4000

2021

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Potassium ions promote hexokinase-II dependent glycolysis

iScience, 2021-04, Vol.24 (4), p.102346, Article 102346

2021

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Crosstalk between TPC2 and IP3R regulates Ca2+ signals

Trends in cell biology, 2024-05, Vol.34 (5), p.352-354

2024

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TRPC-mediated Ca2+ signaling and control of cellular functions

A Coiled-coil Clamp Controls Both Conformation and Clustering of Stromal Interaction Molecule 1 (STIM1)

An optically controlled probe identifies lipid-gating fenestrations within the TRPC3 channel

STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry

A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels

The action of selective CRAC channel blockers is affected by the Orai pore geometry

Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription

Dynamic Coupling of the Putative Coiled-coil Domain of ORAI1 with STIM1 Mediates ORAI1 Channel Activation

Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry

Ca2+ release-activated Ca2+ (CRAC) current, structure, and function

Cholesterol modulates Orai1 channel function

The STIM-Orai Pathway: The Interactions Between STIM and Orai

Cellular interfaces with hydrogen-bonded organic semiconductor hierarchical nanocrystals

A Ca2+ Release-activated Ca2+ (CRAC) Modulatory Domain (CMD) within STIM1 Mediates Fast Ca2+-dependent Inactivation of ORAI1 Channels

Luminal STIM1 Mutants that Cause Tubular Aggregate Myopathy Promote Autophagic Processes

Oxidative Stress-Induced STIM2 Cysteine Modifications Suppress Store-Operated Calcium Entry

2-Aminoethoxydiphenyl Borate Alters Selectivity of Orai3 Channels by Increasing Their Pore Size

Canonical Transient Receptor Potential (TRPC) 1 Acts as a Negative Regulator for Vanilloid TRPV6-mediated Ca2+ Influx

Photo‐Chemical Stimulation of Neurons with Organic Semiconductors

Increased Hydrophobicity at the N Terminus/Membrane Interface Impairs Gating of the Severe Combined Immunodeficiency-related ORAI1 Mutant

Mrs2p forms a high conductance Mg2+ selective channel in mitochondria

Plasticity in Ca²⁺ selectivity of Orai1/Orai3 heteromeric channel

Immobilization of Recombinant Fluorescent Biosensors Permits Imaging of Extracellular Ion Signals

Potassium ions promote hexokinase-II dependent glycolysis

Crosstalk between TPC2 and IP3R regulates Ca2+ signals

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