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Structure-based thresholds of toxicological concern (TTC): guidance for application to substances present at low levels in the diet

Food and chemical toxicology, 2004, Vol.42 (1), p.65-83

2004

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A Toxicogenomics Approach to Identify New Plausible Epigenetic Mechanisms of Ochratoxin A Carcinogenicity in Rat

Toxicological sciences, 2006-01, Vol.89 (1), p.120-134

2006

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Cafestol and kahweol, two coffee specific diterpenes with anticarcinogenic activity

Food and chemical toxicology, 2002-08, Vol.40 (8), p.1155-1163

2002

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Induction of Nrf2-mediated cellular defenses and alteration of phase I activities as mechanisms of chemoprotective effects of coffee in the liver

Food and chemical toxicology, 2008-04, Vol.46 (4), p.1239-1248

2008

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Reduction in Antioxidant Defenses may Contribute to Ochratoxin A Toxicity and Carcinogenicity

Toxicological sciences, 2007-03, Vol.96 (1), p.30-39

2007

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Evidence for a Role of Oxidative Stress in the Carcinogenicity of Ochratoxin A

Journal of Toxicology, 2011-01, Vol.2011 (2011), p.301-315

2011

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Inhibition of the expression and activity of cyclooxygenase-2 by chicory extract

Biochemical and biophysical research communications, 2005-02, Vol.327 (3), p.742-749

2005

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Threshold of toxicological concern for chemical substances present in the diet: A practical tool for assessing the need for toxicity testing

Food and Chemical Toxicology, 2000-02, Vol.38 (2), p.255-312

2000

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Guidance for the safety assessment of botanicals and botanical preparations for use in food and food supplements

Food and chemical toxicology, 2003-12, Vol.41 (12), p.1625-1649

2003

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Application of gastrointestinal modelling to the study of the digestion and transformation of dietary glycidyl esters

Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2013-01, Vol.30 (1), p.69-79

2013

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Identification of nevadensin as an important herb-based constituent inhibiting estragole bioactivation and physiology-based biokinetic modeling of its possible in vivo effect

Toxicology and applied pharmacology, 2010-06, Vol.245 (2), p.179-190

2010

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MAPK-ERK activation in kidney of male rats chronically fed ochratoxin A at a dose causing a significant incidence of renal carcinoma

Toxicology and applied pharmacology, 2007-10, Vol.224 (2), p.174-181

2007

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Coffee diterpenes prevent benzo[ a]pyrene genotoxicity in rat and human culture systems

Biochemical and biophysical research communications, 2003-06, Vol.306 (2), p.488-495

2003

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Involvement of glial cells in the neurotoxicity of parathion and chlorpyrifos

Toxicology and applied pharmacology, 2004-12, Vol.201 (2), p.97-104

2004

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Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells

Food and chemical toxicology, 2001-06, Vol.39 (6), p.549-556

2001

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Matrix modulation of the bioactivation of estragole by different alkenylbenzene-containing herbs and spices and physiologically based biokinetic modeling of possible in vivo effects

Toxicology letters, 2011-08, Vol.205, p.S40-S40

2011

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Coupling H295R with U2OS ERα and AR CALUX bioassays increases steroidogenesis test sensitivity

Toxicology letters, 2021-09, Vol.350, p.S102-S102

2021

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Ochratoxin A carcinogenicity involves a complex network of epigenetic mechanisms

Toxicon (Oxford), 2008-08, Vol.52 (2), p.195-202

2008

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Matrix modulation of the bioactivation of estragole by different alkenylbenzenes-containing herbs and spices and physiologically-based biokinetic modeling of possible in vivo effects

Toxicology (Amsterdam), 2011, Vol.290 (2), p.147-148

2011

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Activation of cytochrome P450 gene expression in the rat brain by phenobarbital-like inducers

The Journal of pharmacology and experimental therapeutics, 2000-09, Vol.294 (3), p.916

2000

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The application of in vitro data in the derivation of the Acceptable Daily Intake of food additives

Food and Chemical Toxicology, 1999-12, Vol.37 (12), p.1175-1197

1999

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A physiologically based biodynamic (PBBD) model for estragole DNA binding in rat liver based on in vitro kinetic data and estragole DNA adduct formation in primary hepatocytes

Toxicology and applied pharmacology, 2010-05, Vol.245 (1), p.57-66

2010

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Regional distribution and expression modulation of cytochrome P-450 and epoxide hydrolase mRNAs in the rat brain

Molecular pharmacology, 1993-11, Vol.44 (5), p.990-996

1993

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Is there an added value to the incorporation of a metabolizing system in biodetection assays for endocrine active substances?

Toxicology letters, 2016-09, Vol.258, p.S153-S153

2016

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Predictive Models for Carcinogenicity and Mutagenicity: Frameworks, State-of-the-Art, and Perspectives

Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews, 2009-05, Vol.27 (2), p.57-90

2009

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Structure-based thresholds of toxicological concern (TTC): guidance for application to substances present at low levels in the diet

A Toxicogenomics Approach to Identify New Plausible Epigenetic Mechanisms of Ochratoxin A Carcinogenicity in Rat

Cafestol and kahweol, two coffee specific diterpenes with anticarcinogenic activity

Induction of Nrf2-mediated cellular defenses and alteration of phase I activities as mechanisms of chemoprotective effects of coffee in the liver

Reduction in Antioxidant Defenses may Contribute to Ochratoxin A Toxicity and Carcinogenicity

Evidence for a Role of Oxidative Stress in the Carcinogenicity of Ochratoxin A

Inhibition of the expression and activity of cyclooxygenase-2 by chicory extract

Threshold of toxicological concern for chemical substances present in the diet: A practical tool for assessing the need for toxicity testing

Guidance for the safety assessment of botanicals and botanical preparations for use in food and food supplements

Application of gastrointestinal modelling to the study of the digestion and transformation of dietary glycidyl esters

Identification of nevadensin as an important herb-based constituent inhibiting estragole bioactivation and physiology-based biokinetic modeling of its possible in vivo effect

MAPK-ERK activation in kidney of male rats chronically fed ochratoxin A at a dose causing a significant incidence of renal carcinoma

Coffee diterpenes prevent benzo[ a]pyrene genotoxicity in rat and human culture systems

Involvement of glial cells in the neurotoxicity of parathion and chlorpyrifos

Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: mechanisms in rat and human cells

Matrix modulation of the bioactivation of estragole by different alkenylbenzene-containing herbs and spices and physiologically based biokinetic modeling of possible in vivo effects

Coupling H295R with U2OS ERα and AR CALUX bioassays increases steroidogenesis test sensitivity

Ochratoxin A carcinogenicity involves a complex network of epigenetic mechanisms

Matrix modulation of the bioactivation of estragole by different alkenylbenzenes-containing herbs and spices and physiologically-based biokinetic modeling of possible in vivo effects

Activation of cytochrome P450 gene expression in the rat brain by phenobarbital-like inducers

The application of in vitro data in the derivation of the Acceptable Daily Intake of food additives

A physiologically based biodynamic (PBBD) model for estragole DNA binding in rat liver based on in vitro kinetic data and estragole DNA adduct formation in primary hepatocytes

Regional distribution and expression modulation of cytochrome P-450 and epoxide hydrolase mRNAs in the rat brain

Is there an added value to the incorporation of a metabolizing system in biodetection assays for endocrine active substances?

Predictive Models for Carcinogenicity and Mutagenicity: Frameworks, State-of-the-Art, and Perspectives

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