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10th international symposium on the synthesis and applications of isotopes and isotopically labelled compounds-applications of isotopes in organic and bioorganic reaction mechanisms Session 4, Wednesday, June 17, 2009

Journal of labelled compounds & radiopharmaceuticals, 2010-05, Vol.53 (5-6), p.275-282

2010

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Asymmetric syntheses of radioactive and stable isotope-labeled β-amino acids

Journal of labelled compounds & radiopharmaceuticals, 2012-05, Vol.55 (5), p.166-170

2012

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ChemInform Abstract: Reactions of Alkyl Azides and Ketones as Mediated by Lewis Acids: Schmidt and Mannich Reactions Using Azide Precursors

ChemInform, 2000-12, Vol.31 (51), p.no-no

2000

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ChemInform Abstract: Regiocontrol in an Intramolecular Schmidt Reaction: Total Synthesis of (+)-Aspidospermidine

ChemInform, 2000-09, Vol.31 (37), p.no-no

2000

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ChemInform Abstract: The Synthesis of an Aminohexyl‐Containing Analogue of the Chromanol Leukotriene B 4 Receptor Antagonist CP‐195543: A Scaffold for the Preparation of Derivatized Analogues

ChemInform, 2000-11, Vol.31 (47)

2000

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ChemInform Abstract: The Synthesis of an Aminohexyl-Containing Analogue of the Chromanol Leukotriene B4 Receptor Antagonist CP-195543: A Scaffold for the Preparation of Derivatized Analogues

ChemInform, 2000-11, Vol.31 (47), p.no-no

2000

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Determination of Antibody–Drug Conjugate Released Payload Species Using Directed in Vitro Assays and Mass Spectrometric Interrogation

Bioconjugate chemistry, 2016-07, Vol.27 (7), p.1645-1654

2016

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Deuterated active pharmaceutical ingredients: A science‐based proposal for synthesis, analysis, and control. Part 1: Framing the problem

Journal of labelled compounds & radiopharmaceuticals, 2019-09, Vol.62 (11), p.690-694

2019

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Deuterium isotope effects on drug pharmacokinetics. I. System-dependent effects of specific deuteration with aldehyde oxidase cleared drugs

Drug metabolism and disposition, 2012-03, Vol.40 (3), p.625-634

2012

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An efficient large‐scale synthesis of 1 H ‐indazole‐[3‐ 14 C]carboxylic acid

Journal of labelled compounds & radiopharmaceuticals, 2007-06, Vol.50 (7), p.675-678

2007

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An efficient large-scale synthesis of 1H-indazole-[3-14C]carboxylic acid

Journal of labelled compounds & radiopharmaceuticals, 2007-06, Vol.50 (7), p.675-678

2007

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Genotoxicity of 2-(3-Chlorobenzyloxy)-6-(piperazinyl)pyrazine, a Novel 5-Hydroxytryptamine 2c Receptor Agonist for the Treatment of Obesity: Role of Metabolic Activation

Drug metabolism and disposition, 2007-06, Vol.35 (6), p.848-858

2007

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Genotoxicity of 2-(3-chlorobenzyloxy)-6-(piperazinyl)pyrazine, a novel 5-hydroxytryptamine2c receptor agonist for the treatment of obesity: role of metabolic activation

Drug metabolism and disposition, 2007-06, Vol.35 (6), p.848

2007

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Identification and Development of an Irreversible Monoacylglycerol Lipase (MAGL) Positron Emission Tomography (PET) Radioligand with High Specificity

Journal of medicinal chemistry, 2019-09, Vol.62 (18), p.8532-8543

2019

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Identification and Profiling of a Selective and Brain Penetrant Radioligand for in Vivo Target Occupancy Measurement of Casein Kinase 1 (CK1) Inhibitors

ACS chemical neuroscience, 2017-09, Vol.8 (9), p.1995-2004

2017

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Identification of a Novel Positron Emission Tomography (PET) Ligand for Imaging β‑Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE-1) in Brain

Journal of medicinal chemistry, 2018-04, Vol.61 (8), p.3296-3308

2018

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Inter- and Intramolecular Addition/Cyclizations of Sulfonamide Anions with Alkynyliodonium Triflates. Synthesis of Dihydropyrrole, Pyrrole, Indole, and Tosylenamide Heterocycles

Journal of organic chemistry, 1996-08, Vol.61 (16), p.5440-5452

1996

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Intramolecular Bicyclizations of Tosylamide-Containing Alkynyliodonium Salts as an Efficient Entry into Polycyclic Alkaloid Skeleta

Journal of the American Chemical Society, 1995-07, Vol.117 (28), p.7544-7545

1995

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Investigation of metabolism and disposition of Pf-05212377: Unexpected sulfonamide hydrolysis explains the lack of ketoconazole mediated DDI

Drug metabolism and pharmacokinetics, 2017-01, Vol.32 (1), p.S52-S52

2017

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Mannich reactions using benzyl azide as a latent N-(phenylamino)methylating agent

Tetrahedron letters, 1998-10, Vol.39 (42), p.7687-7690

1998

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Metabolism of a 5HT 6 Antagonist, 2-Methyl-1-(Phenylsulfonyl)-4-(Piperazin-1-yl)-1H-Benzo[d]imidazole (SAM-760): Impact of Sulfonamide Metabolism on Diminution of a Ketoconazole-Mediated Clinical Drug-Drug Interaction

Drug metabolism and disposition, 2018-07, Vol.46 (7), p.934-942

2018

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Metabolism of a 5HT^sub 6^ Antagonist, 2-Methyl-1-(Phenylsulfonyl)-4-(Piperazin-1-yl)-1H-Benzo[d]imidazole (SAM-760): Impact of Sulfonamide Metabolism on Diminution of a Ketoconazole-Mediated Clinical Drug-Drug Interaction

Drug metabolism and disposition, 2018-07, Vol.46 (7), p.934

2018

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Metabolism of a 5HT6 antagonist, 2-methyl-1-(phenylsulfonyl)-4-(piperazin-1-yl)-1H-benzo[d]imidazole (SAM-760): impact of sulfonamide metabolism on diminution of a ketoconazole mediated clinical drug-drug interaction

Drug metabolism and disposition, 2018-07, Vol.46 (7), p.934-942

2018

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THE METABOLISM OF LUFOTRELVIR, A PRODRUG INVESTIGATED FOR THE TREATMENT OF SARS-COV-2, IN HUMANS FOLLOWING INTRAVENOUS ADMINISTRATION

Drug metabolism and disposition, 2023-07

2023

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The Metabolism of Lufotrelvir, a Prodrug Investigated for the Treatment of SARS-COV2 in Humans Following Intravenous Administration

Drug metabolism and disposition, 2023-10, Vol.51 (10), p.1419-1427

2023

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10th international symposium on the synthesis and applications of isotopes and isotopically labelled compounds-applications of isotopes in organic and bioorganic reaction mechanisms Session 4, Wednesday, June 17, 2009

Asymmetric syntheses of radioactive and stable isotope-labeled β-amino acids

ChemInform Abstract: Reactions of Alkyl Azides and Ketones as Mediated by Lewis Acids: Schmidt and Mannich Reactions Using Azide Precursors

ChemInform Abstract: Regiocontrol in an Intramolecular Schmidt Reaction: Total Synthesis of (+)-Aspidospermidine

ChemInform Abstract: The Synthesis of an Aminohexyl‐Containing Analogue of the Chromanol Leukotriene B 4 Receptor Antagonist CP‐195543: A Scaffold for the Preparation of Derivatized Analogues

ChemInform Abstract: The Synthesis of an Aminohexyl-Containing Analogue of the Chromanol Leukotriene B4 Receptor Antagonist CP-195543: A Scaffold for the Preparation of Derivatized Analogues

Determination of Antibody–Drug Conjugate Released Payload Species Using Directed in Vitro Assays and Mass Spectrometric Interrogation

Deuterated active pharmaceutical ingredients: A science‐based proposal for synthesis, analysis, and control. Part 1: Framing the problem

Deuterium isotope effects on drug pharmacokinetics. I. System-dependent effects of specific deuteration with aldehyde oxidase cleared drugs

An efficient large‐scale synthesis of 1 H ‐indazole‐[3‐ 14 C]carboxylic acid

An efficient large-scale synthesis of 1H-indazole-[3-14C]carboxylic acid

Genotoxicity of 2-(3-Chlorobenzyloxy)-6-(piperazinyl)pyrazine, a Novel 5-Hydroxytryptamine 2c Receptor Agonist for the Treatment of Obesity: Role of Metabolic Activation

Genotoxicity of 2-(3-chlorobenzyloxy)-6-(piperazinyl)pyrazine, a novel 5-hydroxytryptamine2c receptor agonist for the treatment of obesity: role of metabolic activation

Identification and Development of an Irreversible Monoacylglycerol Lipase (MAGL) Positron Emission Tomography (PET) Radioligand with High Specificity

Identification and Profiling of a Selective and Brain Penetrant Radioligand for in Vivo Target Occupancy Measurement of Casein Kinase 1 (CK1) Inhibitors

Identification of a Novel Positron Emission Tomography (PET) Ligand for Imaging β‑Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE-1) in Brain

Inter- and Intramolecular Addition/Cyclizations of Sulfonamide Anions with Alkynyliodonium Triflates. Synthesis of Dihydropyrrole, Pyrrole, Indole, and Tosylenamide Heterocycles

Intramolecular Bicyclizations of Tosylamide-Containing Alkynyliodonium Salts as an Efficient Entry into Polycyclic Alkaloid Skeleta

Investigation of metabolism and disposition of Pf-05212377: Unexpected sulfonamide hydrolysis explains the lack of ketoconazole mediated DDI

Mannich reactions using benzyl azide as a latent N-(phenylamino)methylating agent

Metabolism of a 5HT 6 Antagonist, 2-Methyl-1-(Phenylsulfonyl)-4-(Piperazin-1-yl)-1H-Benzo[d]imidazole (SAM-760): Impact of Sulfonamide Metabolism on Diminution of a Ketoconazole-Mediated Clinical Drug-Drug Interaction

Metabolism of a 5HT^sub 6^ Antagonist, 2-Methyl-1-(Phenylsulfonyl)-4-(Piperazin-1-yl)-1H-Benzo[d]imidazole (SAM-760): Impact of Sulfonamide Metabolism on Diminution of a Ketoconazole-Mediated Clinical Drug-Drug Interaction

Metabolism of a 5HT6 antagonist, 2-methyl-1-(phenylsulfonyl)-4-(piperazin-1-yl)-1H-benzo[d]imidazole (SAM-760): impact of sulfonamide metabolism on diminution of a ketoconazole mediated clinical drug-drug interaction

THE METABOLISM OF LUFOTRELVIR, A PRODRUG INVESTIGATED FOR THE TREATMENT OF SARS-COV-2, IN HUMANS FOLLOWING INTRAVENOUS ADMINISTRATION

The Metabolism of Lufotrelvir, a Prodrug Investigated for the Treatment of SARS-COV2 in Humans Following Intravenous Administration

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