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Tightly regulated ‘all-in-one’ lentiviral vectors for protection of human hematopoietic cells from anticancer chemotherapy

Gene therapy, 2015-11, Vol.22 (11), p.883-892

2015

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Inducible T-cell receptor expression in precursor T cells for leukemia control

Leukemia, 2015-07, Vol.29 (7), p.1530-1542

2015

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Generation of iPSCs from Genetically Corrected Brca2 Hypomorphic Cells: Implications in Cell Reprogramming and Stem Cell Therapy

Stem cells (Dayton, Ohio), 2014-02, Vol.32 (2), p.436-446

2014

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Quantitative assessment of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells engrafted in nonobese diabetic/severe combined immunodeficient mice

Blood, 2000-02, Vol.95 (4), p.1237-1248

2000

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Remarkable leukemogenic potency and quality of a constitutively active neurotrophin receptor, ΔTrkA

Leukemia, 2007-10, Vol.21 (10), p.2171-2180

2007

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Retroviral vector-mediated expression of HoxB4 in hematopoietic cells using a novel coexpression strategy

Gene therapy, 2001-05, Vol.8 (10), p.811-817

2001

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Towards hematopoietic stem cell-mediated protection against infection with human immunodeficiency virus

Gene therapy, 2006-07, Vol.13 (13), p.1037-1047

2006

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Murine Leukemia Induced by Retroviral Gene Marking

Science (American Association for the Advancement of Science), 2002-04, Vol.296 (5567), p.497-497

2002

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Nuclear transformation of Volvox carteri

Proceedings of the National Academy of Sciences - PNAS, 1994-05, Vol.91 (11), p.5080-5084

1994

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Persisting multilineage transgene expression in the clonal progeny of a hematopoietic stem cell

Leukemia, 2002-09, Vol.16 (9), p.1655-1663

2002

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High-level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage on human cord blood CD34+ cells, but impairs lymphomyeloid differentiation

Blood, 2003-03, Vol.101 (5), p.1759-1768

2003

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MDR1 Gene Expression in NOD/SCID Repopulating Cells after Retroviral Gene Transfer under Clinically Relevant Conditions

Molecular therapy, 2000-12, Vol.2 (6), p.609-618

2000

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HOXB4 Enforces Equivalent Fates of ES-Cell-Derived and Adult Hematopoietic Cells

Proceedings of the National Academy of Sciences - PNAS, 2005-08, Vol.102 (34), p.12101-12106

2005

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Improved post-transcriptional processing of an MDR1 retrovirus elevates expression of multidrug resistance in primary human hematopoietic cells

Gene therapy, 2001-02, Vol.8 (3), p.239-246

2001

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Control of Self-Renewal and Differentiation of Hematopoietic Stem Cells: HOXB4 on the Threshold

Annals of the New York Academy of Sciences, 2005-06, Vol.1044 (1), p.6-15

2005

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Retroviral vector integration occurs in preferred genomic targets of human bone marrow–repopulating cells

Blood, 2003-03, Vol.101 (6), p.2191-2198

2003

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Superior gene transfer into solid tumour cells than into human mobilised peripheral blood progenitor cells using helpervirus-free adeno-associated viral vector stocks

European journal of cancer (1990), 1999-07, Vol.35 (7), p.1136-1142

1999

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Unmodified Cre recombinase crosses the membrane

Nucleic acids research, 2002-06, Vol.30 (12), p.e59-59

2002

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Predictable and efficient retroviral gene transfer into murine bone marrow repopulating cells using a defined vector dose

Experimental hematology, 2003-12, Vol.31 (12), p.1206-1214

2003

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Lentiviral gene transfer into peripheral blood–derived CD34+ NOD/SCID-repopulating cells

Blood, 2002-01, Vol.99 (2), p.709-712

2002

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Soluble bone marrow stroma factors improve the efficiency of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells

Human gene therapy, 1999-06, Vol.10 (9), p.1443-1452

1999

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Human multidrug resistance-1 gene transfer to long-term repopulating human mobilized peripheral blood progenitor cells

Bone marrow transplantation (Basingstoke), 2000-05, Vol.25 Suppl 2 (S2), p.S118-S124

2000

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HOXB4 Inhibits Cell Growth in a Dose-Dependent Manner and Sensitizes Cells Towards Extrinsic Cues

Cell cycle (Georgetown, Tex.), 2006-01, Vol.5 (1), p.14-22

2006

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AML1/ETO promotes the maintenance of early hematopoietic progenitors in NOD/SCID mice but does not abrogate their lineage specific differentiation

Leukemia & lymphoma, 2005-02, Vol.46 (2), p.265-272

2005

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Multidrug resistance 1 gene transfer can confer chemoprotection to human peripheral blood progenitor cells engrafted in immunodeficient mice

Human gene therapy, 2002-01, Vol.13 (2), p.233-242

2002

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Tightly regulated ‘all-in-one’ lentiviral vectors for protection of human hematopoietic cells from anticancer chemotherapy

Inducible T-cell receptor expression in precursor T cells for leukemia control

Generation of iPSCs from Genetically Corrected Brca2 Hypomorphic Cells: Implications in Cell Reprogramming and Stem Cell Therapy

Quantitative assessment of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells engrafted in nonobese diabetic/severe combined immunodeficient mice

Remarkable leukemogenic potency and quality of a constitutively active neurotrophin receptor, ΔTrkA

Retroviral vector-mediated expression of HoxB4 in hematopoietic cells using a novel coexpression strategy

Towards hematopoietic stem cell-mediated protection against infection with human immunodeficiency virus

Murine Leukemia Induced by Retroviral Gene Marking

Nuclear transformation of Volvox carteri

Persisting multilineage transgene expression in the clonal progeny of a hematopoietic stem cell

High-level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage on human cord blood CD34+ cells, but impairs lymphomyeloid differentiation

MDR1 Gene Expression in NOD/SCID Repopulating Cells after Retroviral Gene Transfer under Clinically Relevant Conditions

HOXB4 Enforces Equivalent Fates of ES-Cell-Derived and Adult Hematopoietic Cells

Improved post-transcriptional processing of an MDR1 retrovirus elevates expression of multidrug resistance in primary human hematopoietic cells

Control of Self-Renewal and Differentiation of Hematopoietic Stem Cells: HOXB4 on the Threshold

Retroviral vector integration occurs in preferred genomic targets of human bone marrow–repopulating cells

Superior gene transfer into solid tumour cells than into human mobilised peripheral blood progenitor cells using helpervirus-free adeno-associated viral vector stocks

Unmodified Cre recombinase crosses the membrane

Predictable and efficient retroviral gene transfer into murine bone marrow repopulating cells using a defined vector dose

Lentiviral gene transfer into peripheral blood–derived CD34+ NOD/SCID-repopulating cells

Soluble bone marrow stroma factors improve the efficiency of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells

Human multidrug resistance-1 gene transfer to long-term repopulating human mobilized peripheral blood progenitor cells

HOXB4 Inhibits Cell Growth in a Dose-Dependent Manner and Sensitizes Cells Towards Extrinsic Cues

AML1/ETO promotes the maintenance of early hematopoietic progenitors in NOD/SCID mice but does not abrogate their lineage specific differentiation

Multidrug resistance 1 gene transfer can confer chemoprotection to human peripheral blood progenitor cells engrafted in immunodeficient mice

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