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DNA-Encoded Chemical Libraries: Advancing beyond Conventional Small-Molecule Libraries

Accounts of chemical research, 2014-04, Vol.47 (4), p.1247-1255

2014

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Asymmetry of Dual-Display DNA-Encoded Chemical Libraries

Bioconjugate chemistry, 2024-02, Vol.35 (2), p.147-153

2024

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DNA‐encoded chemical libraries – achievements and remaining challenges

FEBS letters, 2018-06, Vol.592 (12), p.2168-2180

2018

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Small Targeted Cytotoxics: Current State and Promises from DNA-Encoded Chemical Libraries

Angewandte Chemie (International ed.), 2013-01, Vol.52 (5), p.1384-1402

International ed. in English, 2013

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Site-Specific Chemical Modification of a Cytokine Mimic for Small Molecule-Based Tumor Targeting

Bioconjugate chemistry, 2023-08, Vol.34 (8), p.1374-1379

2023

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Optimized Reaction Conditions for Amide Bond Formation in DNA-Encoded Combinatorial Libraries

ACS combinatorial science, 2016-08, Vol.18 (8), p.438-443

2016

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Versatile protein recognition by the encoded display of multiple chemical elements on a constant macrocyclic scaffold

Nature chemistry, 2018-04, Vol.10 (4), p.441

2018

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Affinity Enhancement of Protein Ligands by Reversible Covalent Modification of Neighboring Lysine Residues

Angewandte Chemie International Edition, 2018-12, Vol.57 (52), p.17178-17182

International ed. in English, 2018

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Macrocyclic DNA-encoded chemical libraries: a historical perspective

RSC chemical biology, 2022-01, Vol.3 (1), p.7-17

2022

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Complexation with a Cognate Antibody Fragment Facilitates Affinity Measurements of Fluorescein-Linked Small Molecule Ligands

Analytical chemistry (Washington), 2020-08, Vol.92 (15), p.10822-10829

2020

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Dual-display of small molecules enables the discovery of ligand pairs and facilitates affinity maturation

Nature chemistry, 2015-03, Vol.7 (3), p.241

2015

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Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications

Nature chemistry, 2021-06, Vol.13 (6), p.540

2021

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Site-Specific Traceless Coupling of Potent Cytotoxic Drugs to Recombinant Antibodies for Pharmacodelivery

Journal of the American Chemical Society, 2012-04, Vol.134 (13), p.5887-5892

2012

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Modular assembly and encoding strategies for dual-display DNA-encoded chemical libraries

Chemical communications (Cambridge, England), 2021-11, Vol.57 (92), p.12289-12292

2021

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Discovery of Small-Molecule Interleukin-2 Inhibitors from a DNA-Encoded Chemical Library

Chemistry : a European journal, 2012-06, Vol.18 (25), p.7729-7737

2012

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A DNA‐Encoded Chemical Library Based on Peptide Macrocycles

Chemistry : a European journal, 2021-04, Vol.27 (24), p.7160-7167

2021

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20 years of DNA-encoded chemical libraries

Chemical communications (Cambridge, England), 2011-12, Vol.47 (48), p.12747-12753

2011

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A Small-Molecule Inhibitor of Lin28

ACS chemical biology, 2016-10, Vol.11 (10), p.2773-2781

2016

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Comparative evaluation of DNA-encoded chemical selections performed using DNA in single-stranded or double-stranded format

Biochemical and biophysical research communications, 2020-12, Vol.533 (2), p.223-229

2020

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Screening of Three Transition Metal‐Mediated Reactions Compatible with DNA‐Encoded Chemical Libraries

Helvetica chimica acta, 2019-04, Vol.102 (4), p.n/a

2019

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A Specific and Covalent JNK‐1 Ligand Selected from an Encoded Self‐Assembling Chemical Library

Chemistry : a European journal, 2017-06, Vol.23 (34), p.8152-8155

2017

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Specific Inhibitor of Placental Alkaline Phosphatase Isolated from a DNA-Encoded Chemical Library Targets Tumor of the Female Reproductive Tract

Journal of medicinal chemistry, 2021-11, Vol.64 (21), p.15799-15809

2021

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Identification of Structure-Activity Relationships from Screening a Structurally Compact DNA-Encoded Chemical Library

Angewandte Chemie (International ed.), 2015-03, Vol.54 (13), p.3927-3931

International ed. in English, 2015

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Automated screening for small organic ligands using DNA-encoded chemical libraries

Nature protocols, 2016-04, Vol.11 (4), p.764-780

2016

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Systematic Evaluation and Optimization of Modification Reactions of Oligonucleotides with Amines and Carboxylic Acids for the Synthesis of DNA-Encoded Chemical Libraries

Bioconjugate chemistry, 2014-08, Vol.25 (8), p.1453-1461

2014

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DNA-Encoded Chemical Libraries: Advancing beyond Conventional Small-Molecule Libraries

Asymmetry of Dual-Display DNA-Encoded Chemical Libraries

DNA‐encoded chemical libraries – achievements and remaining challenges

Small Targeted Cytotoxics: Current State and Promises from DNA-Encoded Chemical Libraries

Site-Specific Chemical Modification of a Cytokine Mimic for Small Molecule-Based Tumor Targeting

Optimized Reaction Conditions for Amide Bond Formation in DNA-Encoded Combinatorial Libraries

Versatile protein recognition by the encoded display of multiple chemical elements on a constant macrocyclic scaffold

Affinity Enhancement of Protein Ligands by Reversible Covalent Modification of Neighboring Lysine Residues

Macrocyclic DNA-encoded chemical libraries: a historical perspective

Complexation with a Cognate Antibody Fragment Facilitates Affinity Measurements of Fluorescein-Linked Small Molecule Ligands

Dual-display of small molecules enables the discovery of ligand pairs and facilitates affinity maturation

Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications

Site-Specific Traceless Coupling of Potent Cytotoxic Drugs to Recombinant Antibodies for Pharmacodelivery

Modular assembly and encoding strategies for dual-display DNA-encoded chemical libraries

Discovery of Small-Molecule Interleukin-2 Inhibitors from a DNA-Encoded Chemical Library

A DNA‐Encoded Chemical Library Based on Peptide Macrocycles

20 years of DNA-encoded chemical libraries

A Small-Molecule Inhibitor of Lin28

Comparative evaluation of DNA-encoded chemical selections performed using DNA in single-stranded or double-stranded format

Screening of Three Transition Metal‐Mediated Reactions Compatible with DNA‐Encoded Chemical Libraries

A Specific and Covalent JNK‐1 Ligand Selected from an Encoded Self‐Assembling Chemical Library

Specific Inhibitor of Placental Alkaline Phosphatase Isolated from a DNA-Encoded Chemical Library Targets Tumor of the Female Reproductive Tract

Identification of Structure-Activity Relationships from Screening a Structurally Compact DNA-Encoded Chemical Library

Automated screening for small organic ligands using DNA-encoded chemical libraries

Systematic Evaluation and Optimization of Modification Reactions of Oligonucleotides with Amines and Carboxylic Acids for the Synthesis of DNA-Encoded Chemical Libraries

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