UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 33

Sortiert nach

Optimization of a Novel Quinazolinone-Based Series of Transient Receptor Potential A1 (TRPA1) Antagonists Demonstrating Potent in Vivo Activity

Journal of medicinal chemistry, 2016-03, Vol.59 (6), p.2794-2809

2016

Link zum Volltext

Verfügbarkeit prüfen

Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective NaV1.7 Inhibitors

Journal of medicinal chemistry, 2016-09, Vol.59 (17), p.7818-7839

2016

Link zum Volltext

Verfügbarkeit prüfen

New Air-Stable Catalysts for General and Efficient Suzuki−Miyaura Cross-Coupling Reactions of Heteroaryl Chlorides

Organic letters, 2006-04, Vol.8 (9), p.1787-1789

2006

Link zum Volltext

Verfügbarkeit prüfen

Discovery of a biarylamide series of potent, state-dependent NaV1.7 inhibitors

Bioorganic & medicinal chemistry letters, 2017-08, Vol.27 (16), p.3817-3824

2017

Link zum Volltext

Verfügbarkeit prüfen

Synthesis of 4-Substituted Chlorophthalazines, Dihydrobenzoazepinediones, 2-Pyrazolylbenzoic Acid, and 2-Pyrazolylbenzohydrazide via 3-Substituted 3-Hydroxyisoindolin-1-ones

Journal of organic chemistry, 2012-04, Vol.77 (8), p.3887-3906

2012

Link zum Volltext

Verfügbarkeit prüfen

A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explants

Cell chemical biology, 2021-08, Vol.28 (8), p.1158-1168.e13

2021

Link zum Volltext

Verfügbarkeit prüfen

In Vitro and Cellular Probes to Study PARP Enzyme Target Engagement

Cell chemical biology, 2020-07, Vol.27 (7), p.877-887.e14

2020

Link zum Volltext

Verfügbarkeit prüfen

Targeted Degradation of PARP14 Using a Heterobifunctional Small Molecule

Chembiochem : a European journal of chemical biology, 2021-06, Vol.22 (12), p.2107-2110

2021

Link zum Volltext

Verfügbarkeit prüfen

Preclinical Evaluation of AMG 900, a Novel Potent and Highly Selective Pan-Aurora Kinase Inhibitor with Activity in Taxane-Resistant Tumor Cell Lines

Cancer research (Chicago, Ill.), 2010-12, Vol.70 (23), p.9846-9854

2010

Link zum Volltext

Verfügbarkeit prüfen

Forced Self-Modification Assays as a Strategy to Screen MonoPARP Enzymes

SLAS discovery, 2020-03, Vol.25 (3), p.241-252

2020

Link zum Volltext

Verfügbarkeit prüfen

Development of novel azabenzofuran TRPA1 antagonists as in vivo tools

Bioorganic & medicinal chemistry letters, 2014-08, Vol.24 (15), p.3464-3468

2014

Link zum Volltext

Verfügbarkeit prüfen

Discovery of Potent and Highly Selective Thienopyridine Janus Kinase 2 Inhibitors

Journal of medicinal chemistry, 2011-12, Vol.54 (24), p.8440-8450

2011

Link zum Volltext

Verfügbarkeit prüfen

Differential selectivity of JAK2 inhibitors in enzymatic and cellular settings

Experimental hematology, 2013-05, Vol.41 (5), p.491-500

2013

Link zum Volltext

Verfügbarkeit prüfen

Application of P,N-Sulfinyl Imine Ligands to Iridium-Catalyzed Asymmetric Hydrogenation of Olefins

Journal of organic chemistry, 2004-03, Vol.69 (6), p.1800-1802

2004

Link zum Volltext

Verfügbarkeit prüfen

Selective Pharmaceutical Inhibition of PARP14 Mitigates Allergen-Induced IgE and Mucus Overproduction in a Mouse Model of Pulmonary Allergic Response

ImmunoHorizons, 2022-07, Vol.6 (7), p.432-446

2022

Link zum Volltext

Verfügbarkeit prüfen

Self-Condensation of N-tert-Butanesulfinyl Aldimines: Application to the Rapid Asymmetric Synthesis of Biologically Important Amine-Containing Compounds

Organic letters, 2004-09, Vol.6 (20), p.3621-3624

2004

Link zum Volltext

Verfügbarkeit prüfen

Novel Sulfinyl Imine Ligands for Asymmetric Catalysis

Organic letters, 2003-02, Vol.5 (4), p.545-548

2003

Link zum Volltext

Verfügbarkeit prüfen

Discovery of a Potent, Selective, and Orally Bioavailable Pyridinyl-Pyrimidine Phthalazine Aurora Kinase Inhibitor

Journal of medicinal chemistry, 2010-09, Vol.53 (17), p.6368-6377

2010

Link zum Volltext

Verfügbarkeit prüfen

Discovery of triazine-benzimidazoles as selective inhibitors of mTOR

Bioorganic & medicinal chemistry letters, 2011-04, Vol.21 (7), p.2064-2070

2011

Link zum Volltext

Verfügbarkeit prüfen

Synthesis and Resolution of a Novel Chiral Diamine Ligand and Application to Asymmetric Lithiation−Substitution

Organic letters, 2000-04, Vol.2 (7), p.875-878

2000

Link zum Volltext

Verfügbarkeit prüfen

Abstract 1344: Small molecule inhibitor of CD38 modulates its intra- and extracellular functions leading to antitumor activity

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1344-1344

2021

Link zum Volltext

Verfügbarkeit prüfen

Abstract 506: A bespoke screening platform to study mono(ADP-ribosylation)

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.506-506

2020

Link zum Volltext

Verfügbarkeit prüfen

Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective Na V 1.7 Inhibitors

Journal of medicinal chemistry, 2016-09, Vol.59 (17), p.7818-7839

2016

Link zum Volltext

Verfügbarkeit prüfen

New Insights on Assessing Intra-Family Selectivity for Jak2 Inhibitors

Blood, 2011-11, Vol.118 (21), p.5150-5150

2011

Link zum Volltext

Verfügbarkeit prüfen

1 – 25 von 33

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(28)
Mit Volltextzugriff
(33)

Publikationsform

Artikel
(33)

Sprache

Englisch
(33)
Japanisch
(5)

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

5 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Optimization of a Novel Quinazolinone-Based Series of Transient Receptor Potential A1 (TRPA1) Antagonists Demonstrating Potent in Vivo Activity

Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective NaV1.7 Inhibitors

New Air-Stable Catalysts for General and Efficient Suzuki−Miyaura Cross-Coupling Reactions of Heteroaryl Chlorides

Discovery of a biarylamide series of potent, state-dependent NaV1.7 inhibitors

Synthesis of 4-Substituted Chlorophthalazines, Dihydrobenzoazepinediones, 2-Pyrazolylbenzoic Acid, and 2-Pyrazolylbenzohydrazide via 3-Substituted 3-Hydroxyisoindolin-1-ones

A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explants

In Vitro and Cellular Probes to Study PARP Enzyme Target Engagement

Targeted Degradation of PARP14 Using a Heterobifunctional Small Molecule

Preclinical Evaluation of AMG 900, a Novel Potent and Highly Selective Pan-Aurora Kinase Inhibitor with Activity in Taxane-Resistant Tumor Cell Lines

Discovery of N‑(4-(3-(2-Aminopyrimidin-4-yl)pyridin-2-yloxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine (AMG 900), A Highly Selective, Orally Bioavailable Inhibitor of Aurora Kinases with Activity against Multidrug-Resistant Cancer Cell Lines

Forced Self-Modification Assays as a Strategy to Screen MonoPARP Enzymes

Development of novel azabenzofuran TRPA1 antagonists as in vivo tools

Discovery of Potent and Highly Selective Thienopyridine Janus Kinase 2 Inhibitors

Differential selectivity of JAK2 inhibitors in enzymatic and cellular settings

Application of P,N-Sulfinyl Imine Ligands to Iridium-Catalyzed Asymmetric Hydrogenation of Olefins

Selective Pharmaceutical Inhibition of PARP14 Mitigates Allergen-Induced IgE and Mucus Overproduction in a Mouse Model of Pulmonary Allergic Response

Self-Condensation of N-tert-Butanesulfinyl Aldimines: Application to the Rapid Asymmetric Synthesis of Biologically Important Amine-Containing Compounds

Novel Sulfinyl Imine Ligands for Asymmetric Catalysis

Discovery of a Potent, Selective, and Orally Bioavailable Pyridinyl-Pyrimidine Phthalazine Aurora Kinase Inhibitor

Discovery of triazine-benzimidazoles as selective inhibitors of mTOR

Synthesis and Resolution of a Novel Chiral Diamine Ligand and Application to Asymmetric Lithiation−Substitution

Abstract 1344: Small molecule inhibitor of CD38 modulates its intra- and extracellular functions leading to antitumor activity

Abstract 506: A bespoke screening platform to study mono(ADP-ribosylation)

Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective Na V 1.7 Inhibitors

New Insights on Assessing Intra-Family Selectivity for Jak2 Inhibitors

Suchergebnisse filtern