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Efficacy of PD-1 Blockade Is Potentiated by Metformin-Induced Reduction of Tumor Hypoxia

Cancer immunology research, 2017-01, Vol.5 (1), p.9-16

2017

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Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions

Cell reports (Cambridge), 2018-02, Vol.22 (6), p.1509-1521

2018

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Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity

Nature immunology, 2023-02, Vol.24 (2), p.267-279

2023

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CD8 + T cell metabolism in infection and cancer

Nature reviews. Immunology, 2021-11, Vol.21 (11), p.718-738

2021

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The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction

Immunity (Cambridge, Mass.), 2016-09, Vol.45 (3), p.701-703

2016

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Opposing impact of B cell-intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation

The Journal of immunology (1950), 2014-05, Vol.192 (10), p.4525-4532

2014

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Tumor Microenvironment Metabolism: A New Checkpoint for Anti-Tumor Immunity

Vaccines, 2016-12, Vol.4 (4), p.46

2016

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Cutting Edge: BAFF Overexpression Reduces Atherosclerosis via TACI-Dependent B Cell Activation

The Journal of immunology (1950), 2016-12, Vol.197 (12), p.4529-4534

2016

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IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell

Cancer immunology research, 2019-08, Vol.7 (8), p.1258-1266

2019

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Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion

Nature immunology, 2021-02, Vol.22 (2), p.205-215

2021

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The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction

Immunity (Cambridge, Mass.), 2016-08, Vol.45 (2), p.374-388

2016

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4-1BB costimulation induces T cell mitochondrial function and biogenesis enabling cancer immunotherapeutic responses

The Journal of experimental medicine, 2018-04, Vol.215 (4), p.1091-1100

2018

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Hypoxia-inducible factor activity promotes antitumor effector function and tissue residency by CD8+ T cells

The Journal of clinical investigation, 2021-04, Vol.131 (7), p.1-17

2021

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B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6

The Journal of experimental medicine, 2016-05, Vol.213 (5), p.733-750

2016

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Bromodomain protein BRD4 directs and sustains CD8 T cell differentiation during infection

The Journal of experimental medicine, 2021-08, Vol.218 (8)

2021

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Cutting Edge: BAFF Promotes Autoantibody Production via TACI-Dependent Activation of Transitional B Cells

The Journal of immunology (1950), 2016-05, Vol.196 (9), p.3525-3531

2016

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Tumor microenvironmental signals reshape chromatin landscapes to limit the functional potential of exhausted T cells

Science immunology, 2022-08, Vol.7 (74), p.eabj9123

2022

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TACI haploinsufficiency protects against BAFF‐driven humoral autoimmunity in mice

European journal of immunology, 2021-09, Vol.51 (9), p.2225-2236

2021

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Lessons for the Next Generation of Scientists from the Second Annual Arthur and Sandra Irving Cancer Immunology Symposium

Cancer immunology research, 2023-12, Vol.11 (12), p.1571-1577

2023

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B‐cell intrinsic TLR7 signals promote depletion of the marginal zone in a murine model of Wiskott–Aldrich syndrome

European journal of immunology, 2015-10, Vol.45 (10), p.2773-2779

2015

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Abstract 632: The metabolic requirements for effective immunotherapy

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.632-632

2018

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Hypoxia-inducible factor activity promotes antitumor effector function and tissue residency by [CD8.sup.+] T cells

The Journal of clinical investigation, 2021-04, Vol.131 (7)

2021

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Metformin Rescues Age-Associated Decline in Mitochondrial and Immunologic Function in Murine and Human Lymphocytes

Journal of the American College of Surgeons, 2019-10, Vol.229 (4), p.S303-S303

2019

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BAFF over-expression reduces atherosclerosis via TACI-dependent B cell activation

The Journal of immunology (1950), 2016-11, Vol.197 (12), p.4529-4534

2016

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Bromodomain protein BRD4 directs CD8 T cell differentiation during infection and cancer

The Journal of immunology (1950), 2021-05, Vol.206 (1_Supplement), p.67-67.02

2021

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Efficacy of PD-1 Blockade Is Potentiated by Metformin-Induced Reduction of Tumor Hypoxia

Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions

Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity

CD8 + T cell metabolism in infection and cancer

The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction

Opposing impact of B cell-intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation

Tumor Microenvironment Metabolism: A New Checkpoint for Anti-Tumor Immunity

Cutting Edge: BAFF Overexpression Reduces Atherosclerosis via TACI-Dependent B Cell Activation

IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell

Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion

The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction

4-1BB costimulation induces T cell mitochondrial function and biogenesis enabling cancer immunotherapeutic responses

Hypoxia-inducible factor activity promotes antitumor effector function and tissue residency by CD8+ T cells

B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6

Bromodomain protein BRD4 directs and sustains CD8 T cell differentiation during infection

Cutting Edge: BAFF Promotes Autoantibody Production via TACI-Dependent Activation of Transitional B Cells

Tumor microenvironmental signals reshape chromatin landscapes to limit the functional potential of exhausted T cells

TACI haploinsufficiency protects against BAFF‐driven humoral autoimmunity in mice

Lessons for the Next Generation of Scientists from the Second Annual Arthur and Sandra Irving Cancer Immunology Symposium

B‐cell intrinsic TLR7 signals promote depletion of the marginal zone in a murine model of Wiskott–Aldrich syndrome

Abstract 632: The metabolic requirements for effective immunotherapy

Hypoxia-inducible factor activity promotes antitumor effector function and tissue residency by [CD8.sup.+] T cells

Metformin Rescues Age-Associated Decline in Mitochondrial and Immunologic Function in Murine and Human Lymphocytes

BAFF over-expression reduces atherosclerosis via TACI-dependent B cell activation

Bromodomain protein BRD4 directs CD8 T cell differentiation during infection and cancer

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