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Red-Shifted FRET Biosensors for High-Throughput Fluorescence Lifetime Screening

Biosensors (Basel), 2018-10, Vol.8 (4), p.99

2018

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Fluorescence-Based TNFR1 Biosensor for Monitoring Receptor Structural and Conformational Dynamics and Discovery of Small Molecule Modulators

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2248, p.121

2021

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Noncompetitive inhibitors of TNFR1 probe conformational activation states

Science signaling, 2019-07, Vol.12 (592)

2019

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Targeting protein-protein interactions for therapeutic discovery via FRET-based high-throughput screening in living cells

Scientific reports, 2018-08, Vol.8 (1), p.12560-13, Article 12560

2018

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An ex vivo gene therapy approach to treat muscular dystrophy using inducible pluripotent stem cells

Nature communications, 2013, Vol.4 (1), p.1549-1549, Article 1549

2013

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Discovery of enzyme modulators via high-throughput time-resolved FRET in living cells

Journal of biomolecular screening, 2014-02, Vol.19 (2), p.215-222

2014

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Eye tracking for classification of concussion in adults and pediatrics

Frontiers in neurology, 2022-12, Vol.13, p.1039955-1039955

2022

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Live-Cell Cardiac-Specific High-Throughput Screening Platform for Drug-Like Molecules That Enhance Ca2+ Transport

Cells (Basel, Switzerland), 2020-05, Vol.9 (5), p.1170

2020

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Consequences of inequity in the neurosurgical workforce: Lessons from traumatic brain injury

Frontiers in surgery, 2022-09, Vol.9, p.962867-962867

2022

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An Innovative High-Throughput Screening Approach for Discovery of Small Molecules That Inhibit TNF Receptors

SLAS discovery, 2017-09, Vol.22 (8), p.950-961

2017

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High-Throughput Spectral and Lifetime-Based FRET Screening in Living Cells to Identify Small-Molecule Effectors of SERCA

SLAS discovery, 2017-03, Vol.22 (3), p.262-273

2017

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103 Participants in Clinical Trials for Traumatic Brain Injury Are Not Representative of the Injured Population

Neurosurgery, 2022-04, Vol.68 (Supplement_1), p.28-28

2022

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Biophysics of SERCA2a DWORF Complex and Implications for Therapeutic Design

Biophysical journal, 2019-02, Vol.116 (3), p.117a-117a

2019

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Simulation and FRET Analyses of SERCA, Phospohlamban, and Sarcolipin Complexes

Biophysical journal, 2020-02, Vol.118 (3), p.442a-442a

2020

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Biophysics of the SERCA2A/DWORF Complex, Implications for Treatment of Heart Failure

Biophysical journal, 2020-02, Vol.118 (3), p.593a-593a

2020

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Live-Cell FRET Biosensors for High-Throughput Screening Targeting the SERCA2a/Plb Complex

Biophysical journal, 2019-02, Vol.116 (3), p.128a-128a

2019

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Single-Polypeptide SERCA-Phospholamban Fused FRET Biosensor for High-throughput Cardiac-specific Drug Discovery

Biophysical journal, 2020-02, Vol.118 (3), p.314a-315a

2020

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Biophysics of SERCA2a/DWORF Complex and Implications for Therapeutic Design

Biophysical journal, 2018-02, Vol.114 (3), p.501a-501a

2018

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Red-Shifted Fluorescent Proteins Improve FRET Biosensors for High-throughput Fluorescence Lifetime Screening

Biophysical journal, 2018-02, Vol.114 (3), p.171a-171a

2018

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Manipulation of Tau Oligomerization and Aggregation Characterized by Time-Resolved FRET

Biophysical journal, 2018-02, Vol.114 (3), p.585a-586a

2018

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High-Throughput FRET Screening in Living Cells Based on Lifetime Detection to Identify Small-Molecule Effectors of Serca

Biophysical journal, 2020-02, Vol.118 (3), p.469a-469a

2020

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Targeting the Serca-Plb Complex using FRET in Living Cells

Biophysical journal, 2017-02, Vol.112 (3), p.570a-570a

2017

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Discovery of SERCA2a/PLB Activators and Inhibitors by Structure-Based High-throughput Screening using Live Cell FRET Biosensors

Biophysical journal, 2018-02, Vol.114 (3), p.147a-147a

2018

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Targeting the SERCA-PLB Complex for Treatment of Heart Failure

Biophysical journal, 2016-02, Vol.110 (3), p.509a-509a

2016

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Inhibition of Tumor Necrosis Factor Receptor 1 Signaling by Small Molecules

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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Red-Shifted FRET Biosensors for High-Throughput Fluorescence Lifetime Screening

Fluorescence-Based TNFR1 Biosensor for Monitoring Receptor Structural and Conformational Dynamics and Discovery of Small Molecule Modulators

Noncompetitive inhibitors of TNFR1 probe conformational activation states

Targeting protein-protein interactions for therapeutic discovery via FRET-based high-throughput screening in living cells

An ex vivo gene therapy approach to treat muscular dystrophy using inducible pluripotent stem cells

Discovery of enzyme modulators via high-throughput time-resolved FRET in living cells

Eye tracking for classification of concussion in adults and pediatrics

Live-Cell Cardiac-Specific High-Throughput Screening Platform for Drug-Like Molecules That Enhance Ca2+ Transport

Consequences of inequity in the neurosurgical workforce: Lessons from traumatic brain injury

An Innovative High-Throughput Screening Approach for Discovery of Small Molecules That Inhibit TNF Receptors

High-Throughput Spectral and Lifetime-Based FRET Screening in Living Cells to Identify Small-Molecule Effectors of SERCA

103 Participants in Clinical Trials for Traumatic Brain Injury Are Not Representative of the Injured Population

Biophysics of SERCA2a DWORF Complex and Implications for Therapeutic Design

Simulation and FRET Analyses of SERCA, Phospohlamban, and Sarcolipin Complexes

Biophysics of the SERCA2A/DWORF Complex, Implications for Treatment of Heart Failure

Live-Cell FRET Biosensors for High-Throughput Screening Targeting the SERCA2a/Plb Complex

Single-Polypeptide SERCA-Phospholamban Fused FRET Biosensor for High-throughput Cardiac-specific Drug Discovery

Biophysics of SERCA2a/DWORF Complex and Implications for Therapeutic Design

Red-Shifted Fluorescent Proteins Improve FRET Biosensors for High-throughput Fluorescence Lifetime Screening

Manipulation of Tau Oligomerization and Aggregation Characterized by Time-Resolved FRET

High-Throughput FRET Screening in Living Cells Based on Lifetime Detection to Identify Small-Molecule Effectors of Serca

Targeting the Serca-Plb Complex using FRET in Living Cells

Discovery of SERCA2a/PLB Activators and Inhibitors by Structure-Based High-throughput Screening using Live Cell FRET Biosensors

Targeting the SERCA-PLB Complex for Treatment of Heart Failure

Inhibition of Tumor Necrosis Factor Receptor 1 Signaling by Small Molecules

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