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Inhibitors of the Sec61 Complex and Novel High Throughput Screening Strategies to Target the Protein Translocation Pathway

International journal of molecular sciences, 2021-11, Vol.22 (21), p.12007

2021

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Evidence for Heterodimerization and Functional Interaction of the Angiotensin Type 2 Receptor and the Receptor MAS

Hypertension (Dallas, Tex. 1979), 2017-06, Vol.69 (6), p.1128-1135

2017

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Primary and secondary thyroid hormone transporters

Thyroid research, 2011-08, Vol.4 Suppl 1 (S1), p.S7-S7, Article S7

2011

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Thyrotropin Receptor: Allosteric Modulators Illuminate Intramolecular Signaling Mechanisms at the Interface of Ecto- and Transmembrane Domain

Molecular pharmacology, 2019-10, Vol.96 (4), p.452-462

2019

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The Specific Monomer/Dimer Equilibrium of the Corticotropin-releasing Factor Receptor Type 1 Is Established in the Endoplasmic Reticulum

The Journal of biological chemistry, 2014-08, Vol.289 (35), p.24250-24262

2014

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A new variant in signal peptide of the human luteinizing hormone receptor (LHCGR) affects receptor biogenesis causing leydig cell hypoplasia

Human molecular genetics, 2015-11, Vol.24 (21), p.6003-6012

2015

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Signaling-sensitive amino acids surround the allosteric ligand binding site of the thyrotropin receptor

The FASEB journal, 2010-07, Vol.24 (7), p.2347-2354

2010

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The protease-activated receptor 1 possesses a functional and cleavable signal peptide which is necessary for receptor expression

FEBS letters, 2012-07, Vol.586 (16), p.2351-2359

2012

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The Corticotropin-releasing Factor Receptor Type 2a Contains an N-terminal Pseudo Signal Peptide

The Journal of biological chemistry, 2006-08, Vol.281 (34), p.24910-24921

2006

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Disease‐causing V2 Vasopressin Receptors are Retained in Different Compartments of the Early Secretory Pathway

Traffic (Copenhagen, Denmark), 2004-12, Vol.5 (12), p.993-1005

2004

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Use of a sequential high throughput screening assay to identify novel inhibitors of the eukaryotic SRP-Sec61 targeting/translocation pathway

PloS one, 2018-12, Vol.13 (12), p.e0208641-e0208641

2018

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Defining a conformational consensus motif in cotransin-sensitive signal sequences: a proteomic and site-directed mutagenesis study

PloS one, 2015-03, Vol.10 (3), p.e0120886

2015

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Functional Significance of the Signal Peptides of Corticotropin-Releasing Factor Receptors

Current molecular pharmacology, 2017-01, Vol.10 (4), p.311

2017

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The Golgi Protein RCAS1 Controls Cell Surface Expression of Tumor-associated O-Linked Glycan Antigens

The Journal of biological chemistry, 2003-06, Vol.278 (25), p.22998-23007

2003

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The hydrophobic amino acid residues in the membrane-proximal C tail of the G protein-coupled vasopressin V2 receptor are necessary for transport-competent receptor folding

FEBS letters, 2005-09, Vol.579 (23), p.5227-5235

2005

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A New Highly Thyrotropin Receptor-Selective Small-Molecule Antagonist with Potential for the Treatment of Graves' Orbitopathy

Thyroid (New York, N.Y.), 2019-01, Vol.29 (1), p.111

2019

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Non-HLA antibodies targeting angiotensin II Type 1 receptor and endothelin-1 Type A receptors induce endothelial injury via β2-arrestin link to mTOR pathway

Kidney international, 2022-03, Vol.101 (3), p.498-509

2022

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Modulating TSH Receptor Signaling for Therapeutic Benefit

European thyroid journal, 2020-12, Vol.9 (Suppl 1), p.66-77

2020

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Differences between lutropin‐mediated and choriogonadotropin‐mediated receptor activation

The FEBS journal, 2014-03, Vol.281 (5), p.1479-1492

2014

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N-Terminal Signal Peptides of G Protein-Coupled Receptors: Significance for Receptor Biosynthesis, Trafficking, and Signal Transduction

Progress in molecular biology and translational science, 2015, Vol.132, p.267-287

2015

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A Proteomic Study on the Membrane Protein Fraction of T Cells Confirms High Substrate Selectivity for the ER Translocation Inhibitor Cyclotriazadisulfonamide

Molecular & cellular proteomics, 2021-01, Vol.20, p.100144-100144, Article 100144

2021

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HCMV-encoded chemokine receptor US28 employs multiple routes for internalization

Biochemical and biophysical research communications, 2004-09, Vol.322 (1), p.42-49

2004

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The Pseudo Signal Peptide of the Corticotropin-releasing Factor Receptor Type 2A Prevents Receptor Oligomerization

The Journal of biological chemistry, 2012-08, Vol.287 (32), p.27265-27274

2012

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The VirB/VirD4 type IV secretion system of Bartonella is essential for establishing intraerythrocytic infection

Molecular microbiology, 2002-11, Vol.46 (4), p.1053-1067

2002

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Evidence of G-protein-coupled receptor and substrate transporter heteromerization at a single molecule level

Cellular and molecular life sciences : CMLS, 2018-06, Vol.75 (12), p.2227-2239

2018

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Inhibitors of the Sec61 Complex and Novel High Throughput Screening Strategies to Target the Protein Translocation Pathway

Evidence for Heterodimerization and Functional Interaction of the Angiotensin Type 2 Receptor and the Receptor MAS

Primary and secondary thyroid hormone transporters

Thyrotropin Receptor: Allosteric Modulators Illuminate Intramolecular Signaling Mechanisms at the Interface of Ecto- and Transmembrane Domain

The Specific Monomer/Dimer Equilibrium of the Corticotropin-releasing Factor Receptor Type 1 Is Established in the Endoplasmic Reticulum

A new variant in signal peptide of the human luteinizing hormone receptor (LHCGR) affects receptor biogenesis causing leydig cell hypoplasia

Signaling-sensitive amino acids surround the allosteric ligand binding site of the thyrotropin receptor

The protease-activated receptor 1 possesses a functional and cleavable signal peptide which is necessary for receptor expression

The Corticotropin-releasing Factor Receptor Type 2a Contains an N-terminal Pseudo Signal Peptide

Disease‐causing V2 Vasopressin Receptors are Retained in Different Compartments of the Early Secretory Pathway

Use of a sequential high throughput screening assay to identify novel inhibitors of the eukaryotic SRP-Sec61 targeting/translocation pathway

Defining a conformational consensus motif in cotransin-sensitive signal sequences: a proteomic and site-directed mutagenesis study

Functional Significance of the Signal Peptides of Corticotropin-Releasing Factor Receptors

The Golgi Protein RCAS1 Controls Cell Surface Expression of Tumor-associated O-Linked Glycan Antigens

The hydrophobic amino acid residues in the membrane-proximal C tail of the G protein-coupled vasopressin V2 receptor are necessary for transport-competent receptor folding

A New Highly Thyrotropin Receptor-Selective Small-Molecule Antagonist with Potential for the Treatment of Graves' Orbitopathy

Non-HLA antibodies targeting angiotensin II Type 1 receptor and endothelin-1 Type A receptors induce endothelial injury via β2-arrestin link to mTOR pathway

Modulating TSH Receptor Signaling for Therapeutic Benefit

Differences between lutropin‐mediated and choriogonadotropin‐mediated receptor activation

N-Terminal Signal Peptides of G Protein-Coupled Receptors: Significance for Receptor Biosynthesis, Trafficking, and Signal Transduction

A Proteomic Study on the Membrane Protein Fraction of T Cells Confirms High Substrate Selectivity for the ER Translocation Inhibitor Cyclotriazadisulfonamide

HCMV-encoded chemokine receptor US28 employs multiple routes for internalization

The Pseudo Signal Peptide of the Corticotropin-releasing Factor Receptor Type 2A Prevents Receptor Oligomerization

The VirB/VirD4 type IV secretion system of Bartonella is essential for establishing intraerythrocytic infection

Evidence of G-protein-coupled receptor and substrate transporter heteromerization at a single molecule level

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