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Pharmacological targeting of endoplasmic reticulum stress signaling in cancer

Biochemical pharmacology, 2013-03, Vol.85 (5), p.653-666

Schönthal, Axel H.

2013

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Intranasal Perillyl Alcohol for Glioma Therapy: Molecular Mechanisms and Clinical Development

International journal of molecular sciences, 2018-12, Vol.19 (12), p.3905

2018

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Endoplasmic Reticulum Stress : Its Role in Disease and Novel Prospects for Therapy

Scientifica (Cairo), 2012-01, Vol.2012 (2012), p.1-26

2012

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The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas

Cancer research (Chicago, Ill.), 2007-10, Vol.67 (20), p.9809-9816

2007

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Preclinical studies of a novel snake venom-derived recombinant disintegrin with antitumor activity: A review

Biochemical pharmacology, 2020-11, Vol.181, p.114149-114149, Article 114149

2020

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Developing a clinically relevant radiosensitizer for temozolomide-resistant gliomas

PloS one, 2020-09, Vol.15 (9), p.e0238238-e0238238

2020

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Endoplasmic reticulum stress and autophagy as targets for cancer therapy

Cancer letters, 2009-03, Vol.275 (2), p.163-169

Schönthal, Axel H

2009

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Heat shock protein-90alpha (Hsp90α) stabilizes hypoxia-inducible factor-1α (HIF-1α) in support of spermatogenesis and tumorigenesis

Cancer gene therapy, 2021-09, Vol.28 (9), p.1058-1070

2021

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Bioorthogonal Profiling of a Cancer Cell Proteome Identifies a Large Set of 3‑Bromopyruvate Targets beyond Glycolysis

ACS chemical biology, 2018-11, Vol.13 (11), p.3054-3058

2018

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Perillyl Alcohol and Its Drug-Conjugated Derivatives as Potential Novel Methods of Treating Brain Metastases

International journal of molecular sciences, 2016-09, Vol.17 (9), p.1463-1463

2016

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LRP-1 receptor combines EGFR signalling and eHsp90α autocrine to support constitutive breast cancer cell motility in absence of blood supply

Scientific reports, 2022-07, Vol.12 (1), p.12006-12006, Article 12006

2022

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Heterogeneous Responses and Isoform Compensation Dim the Therapeutic Window of Hsp90 ATP-Binding Inhibitors in Cancer

Molecular and cellular biology, 2022-02, Vol.42 (2), p.e0045921-e0045921

2022

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HIV-1 Protease Inhibitors Nelfinavir and Atazanavir Induce Malignant Glioma Death by Triggering Endoplasmic Reticulum Stress

Cancer research (Chicago, Ill.), 2007-11, Vol.67 (22), p.10920-10928

2007

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Stress Chaperone GRP78/BiP Confers Chemoresistance to Tumor-Associated Endothelial Cells

Molecular cancer research, 2008-08, Vol.6 (8), p.1268-1275

2008

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Adverse effects of concentrated green tea extracts

Molecular nutrition & food research, 2011-06, Vol.55 (6), p.874-885

Schönthal, Axel H.

2011

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From the groin to the brain: a transfemoral path to blood-brain barrier opening

Oncotarget, 2023-05, Vol.14 (1), p.413-416

2023

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Green tea polyphenols block the anticancer effects of bortezomib and other boronic acid–based proteasome inhibitors

Blood, 2009-06, Vol.113 (23), p.5927-5937

2009

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Induction of Pro-Apoptotic Endoplasmic Reticulum Stress in Multiple Myeloma Cells by NEO214, Perillyl Alcohol Conjugated to Rolipram

International journal of molecular sciences, 2018-01, Vol.19 (1), p.277

2018

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Inhibition of autophagy and induction of breast cancer cell death by mefloquine, an antimalarial agent

Cancer letters, 2012-12, Vol.326 (2), p.143-154

2012

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Efficient brain targeting and therapeutic intracranial activity of bortezomib through intranasal co-delivery with NEO100 in rodent glioblastoma models

Journal of neurosurgery, 2020-03, Vol.132 (3), p.959-967

2020

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Enhanced brain entry of checkpoint-inhibitory therapeutic antibodies facilitated by intraarterial NEO100 in mouse models of brain-localized malignancies

Journal of neurosurgery, 2023-09, Vol.139 (3), p.1-830

2023

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Therapeutic effect of NEO400, perillyl alcohol conjugated to linoleic acid, in a mouse model of UV-induced skin damage

Photochemistry and photobiology, 2024-07

2024

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Quinoline-based antimalarial drugs: a novel class of autophagy inhibitors

Neurosurgical focus, 2015-03, Vol.38 (3), p.E12-E12

2015

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Characterization of cerebrospinal fluid markers as indicators of spinal cord ischemia following an endovascular aortic aneurysm repair procedure

Journal of neurosurgery, 2024-11, p.1-10

2024

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NEO212 Inhibits Migration and Invasion of Glioma Stem Cells

Molecular cancer therapeutics, 2018-03, Vol.17 (3), p.625-637

2018

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Pharmacological targeting of endoplasmic reticulum stress signaling in cancer

Intranasal Perillyl Alcohol for Glioma Therapy: Molecular Mechanisms and Clinical Development

Endoplasmic Reticulum Stress : Its Role in Disease and Novel Prospects for Therapy

The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas

Preclinical studies of a novel snake venom-derived recombinant disintegrin with antitumor activity: A review

Developing a clinically relevant radiosensitizer for temozolomide-resistant gliomas

Endoplasmic reticulum stress and autophagy as targets for cancer therapy

Heat shock protein-90alpha (Hsp90α) stabilizes hypoxia-inducible factor-1α (HIF-1α) in support of spermatogenesis and tumorigenesis

Bioorthogonal Profiling of a Cancer Cell Proteome Identifies a Large Set of 3‑Bromopyruvate Targets beyond Glycolysis

Perillyl Alcohol and Its Drug-Conjugated Derivatives as Potential Novel Methods of Treating Brain Metastases

LRP-1 receptor combines EGFR signalling and eHsp90α autocrine to support constitutive breast cancer cell motility in absence of blood supply

Heterogeneous Responses and Isoform Compensation Dim the Therapeutic Window of Hsp90 ATP-Binding Inhibitors in Cancer

HIV-1 Protease Inhibitors Nelfinavir and Atazanavir Induce Malignant Glioma Death by Triggering Endoplasmic Reticulum Stress

Stress Chaperone GRP78/BiP Confers Chemoresistance to Tumor-Associated Endothelial Cells

Adverse effects of concentrated green tea extracts

From the groin to the brain: a transfemoral path to blood-brain barrier opening

Green tea polyphenols block the anticancer effects of bortezomib and other boronic acid–based proteasome inhibitors

Induction of Pro-Apoptotic Endoplasmic Reticulum Stress in Multiple Myeloma Cells by NEO214, Perillyl Alcohol Conjugated to Rolipram

Inhibition of autophagy and induction of breast cancer cell death by mefloquine, an antimalarial agent

Efficient brain targeting and therapeutic intracranial activity of bortezomib through intranasal co-delivery with NEO100 in rodent glioblastoma models

Enhanced brain entry of checkpoint-inhibitory therapeutic antibodies facilitated by intraarterial NEO100 in mouse models of brain-localized malignancies

Therapeutic effect of NEO400, perillyl alcohol conjugated to linoleic acid, in a mouse model of UV-induced skin damage

Quinoline-based antimalarial drugs: a novel class of autophagy inhibitors

Characterization of cerebrospinal fluid markers as indicators of spinal cord ischemia following an endovascular aortic aneurysm repair procedure

NEO212 Inhibits Migration and Invasion of Glioma Stem Cells

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