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Small-molecule control of antibody N-glycosylation in engineered mammalian cells

Nature chemical biology, 2019-07, Vol.15 (7), p.730-736

2019

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Reactivity-driven cleanup of 2-Aminobenzamide derivatized oligosaccharides

Analytical biochemistry, 2018-04, Vol.546, p.23-27

2018

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Transient CHO expression platform for robust antibody production and its enhanced N‐glycan sialylation on therapeutic glycoproteins

Biotechnology progress, 2019-01, Vol.35 (1), p.e2724-n/a

2019

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Complementation of essential yeast GPI mannosyltransferase mutations suggests a novel specificity for certain Trypanosoma and Plasmodium PigB proteins

PloS one, 2014-01, Vol.9 (1), p.e87673

2014

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yeast integral membrane protein Apq12 potentially links membrane dynamics to assembly of nuclear pore complexes

The Journal of cell biology, 2007-08, Vol.178 (5), p.799-812

2007

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Dissecting N-Glycosylation Dynamics in Chinese Hamster Ovary Cells Fed-batch Cultures using Time Course Omics Analyses

iScience, 2019-02, Vol.12, p.102-120

2019

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New Opportunities in Glycan Engineering for Therapeutic Proteins

Antibodies (Basel), 2022-01, Vol.11 (1), p.5

2022

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Integral membrane proteins Brr6 and Apq12 link assembly of the nuclear pore complex to lipid homeostasis in the endoplasmic reticulum

Journal of cell science, 2010-01, Vol.123 (1), p.141-151

2010

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DEAD-Box RNA Helicase Dbp5 Functions in Translation Termination

Science (American Association for the Advancement of Science), 2007-02, Vol.315 (5812), p.646-649

2007

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Strategic deployment of CHO expression platforms to deliver Pfizer's Monoclonal Antibody Portfolio

Biotechnology progress, 2017-11, Vol.33 (6), p.1463-1467

2017

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A genetic off‐target event in a site‐specific integration cell line expressing monoclonal antibody has no impact on commercial suitability

Biotechnology progress, 2023-03, Vol.39 (2), p.e3320-n/a

2023

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The impact of expression vector position on transgene transcription allows for rational expression vector design in a targeted integration system

Biotechnology journal, 2023-09, Vol.18 (9), p.e2300038-n/a

2023

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Analytical subcloning of a clonal cell line demonstrates cellular heterogeneity that does not impact process consistency or robustness

Biotechnology progress, 2018-05, Vol.34 (3), p.602-612

2018

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A high‐fidelity, dual site‐specific integration system in CHO cells by a Bxb1 recombinase

Biotechnology journal, 2024-01, Vol.19 (2), p.e2300410-n/a

2024

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Transport of messenger RNA from the nucleus to the cytoplasm

Current opinion in cell biology, 2006-06, Vol.18 (3), p.299-306

2006

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Impacts of fast production of afucosylated antibodies and Fc mutants in ExpiCHO-S™ for enhancing FcγRIIIa binding and NK cell activation

Journal of biotechnology, 2022-12, Vol.360, p.79-91

2022

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Genetic rearrangement during site specific integration event facilitates cell line development of a bispecific molecule

Biotechnology progress, 2021-07, Vol.37 (4), p.e3158-n/a

2021

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Structure-function relationships of the soluble form of the antiaging protein Klotho have therapeutic implications for managing kidney disease

The Journal of biological chemistry, 2020-03, Vol.295 (10), p.3115-3133

2020

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The Dbp5 cycle at the nuclear pore complex during mRNA export I: dbp5 mutants with defects in RNA binding and ATP hydrolysis define key steps for Nup159 and Gle1

Genes & development, 2011-05, Vol.25 (10), p.1052-1064

2011

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Unravelling mRNA export

Nature cell biology, 2006-07, Vol.8 (7), p.645-647

2006

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Synthetic Genetic Array Analysis in Saccharomyces cerevisiae Provides Evidence for an Interaction Between RAT8/DBP5 and Genes Encoding P-Body Components

Genetics (Austin), 2008-08, Vol.179 (4), p.1945-1955

2008

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Uptake of radiolabeled GlcNAc into Saccharomyces cerevisiae via native hexose transporters and its in vivo incorporation into GPI precursors in cells expressing heterologous GlcNAc kinase

FEMS yeast research, 2012-05, Vol.12 (3), p.305-316

2012

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Strategic deployment of C HO expression platforms to deliver Pfizer's Monoclonal Antibody Portfolio

Biotechnology progress, 2017-11, Vol.33 (6), p.1463-1467

2017

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Complementation of Essential Yeast GPI Mannosyltransferase Mutations Suggests a Novel Specificity for Certain Trypanosoma and Plasmodium PigB Proteins: e87673

PloS one, 2014-01, Vol.9 (1)

2014

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Dissecting the Dynamics of N-Linked Glycosylation in Fed-Batch Cultures of Chinese Hamster Ovary Cells Through Time Course Omics Analyses

SSRN Electronic Journal

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Small-molecule control of antibody N-glycosylation in engineered mammalian cells

Reactivity-driven cleanup of 2-Aminobenzamide derivatized oligosaccharides

Transient CHO expression platform for robust antibody production and its enhanced N‐glycan sialylation on therapeutic glycoproteins

Complementation of essential yeast GPI mannosyltransferase mutations suggests a novel specificity for certain Trypanosoma and Plasmodium PigB proteins

yeast integral membrane protein Apq12 potentially links membrane dynamics to assembly of nuclear pore complexes

Dissecting N-Glycosylation Dynamics in Chinese Hamster Ovary Cells Fed-batch Cultures using Time Course Omics Analyses

New Opportunities in Glycan Engineering for Therapeutic Proteins

Integral membrane proteins Brr6 and Apq12 link assembly of the nuclear pore complex to lipid homeostasis in the endoplasmic reticulum

DEAD-Box RNA Helicase Dbp5 Functions in Translation Termination

Strategic deployment of CHO expression platforms to deliver Pfizer's Monoclonal Antibody Portfolio

A genetic off‐target event in a site‐specific integration cell line expressing monoclonal antibody has no impact on commercial suitability

The impact of expression vector position on transgene transcription allows for rational expression vector design in a targeted integration system

Analytical subcloning of a clonal cell line demonstrates cellular heterogeneity that does not impact process consistency or robustness

A high‐fidelity, dual site‐specific integration system in CHO cells by a Bxb1 recombinase

Transport of messenger RNA from the nucleus to the cytoplasm

Impacts of fast production of afucosylated antibodies and Fc mutants in ExpiCHO-S™ for enhancing FcγRIIIa binding and NK cell activation

Genetic rearrangement during site specific integration event facilitates cell line development of a bispecific molecule

Structure-function relationships of the soluble form of the antiaging protein Klotho have therapeutic implications for managing kidney disease

The Dbp5 cycle at the nuclear pore complex during mRNA export I: dbp5 mutants with defects in RNA binding and ATP hydrolysis define key steps for Nup159 and Gle1

Unravelling mRNA export

Synthetic Genetic Array Analysis in Saccharomyces cerevisiae Provides Evidence for an Interaction Between RAT8/DBP5 and Genes Encoding P-Body Components

Uptake of radiolabeled GlcNAc into Saccharomyces cerevisiae via native hexose transporters and its in vivo incorporation into GPI precursors in cells expressing heterologous GlcNAc kinase

Strategic deployment of C HO expression platforms to deliver Pfizer's Monoclonal Antibody Portfolio

Complementation of Essential Yeast GPI Mannosyltransferase Mutations Suggests a Novel Specificity for Certain Trypanosoma and Plasmodium PigB Proteins: e87673

Dissecting the Dynamics of N-Linked Glycosylation in Fed-Batch Cultures of Chinese Hamster Ovary Cells Through Time Course Omics Analyses

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