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Oxidative Stress and Neurotoxicity

Chemical research in toxicology, 2008-01, Vol.21 (1), p.172-188

2008

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Protein Adducts Generated from Products of Lipid Oxidation: Focus on HNE and ONE

Drug metabolism reviews, 2006-01, Vol.38 (4), p.651-675

2006

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Chemistry and biochemistry of oxidative stress in neurodegenerative disease

Current medicinal chemistry, 2001-06, Vol.8 (7), p.721-738

2001

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4-Oxo-2-nonenal Is Both More Neurotoxic and More Protein Reactive than 4-Hydroxy-2-nonenal

Chemical research in toxicology, 2005-08, Vol.18 (8), p.1219-1231

2005

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Iron Accumulation in Alzheimer Disease is a Source of Redox-Generated Free Radicals

Proceedings of the National Academy of Sciences - PNAS, 1997-09, Vol.94 (18), p.9866-9868

1997

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Widespread Peroxynitrite-Mediated Damage in Alzheimer's Disease

The Journal of neuroscience, 1997-04, Vol.17 (8), p.2653-2657

1997

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Copper Mediates Dityrosine Cross-Linking of Alzheimer's Amyloid-β

Biochemistry (Easton), 2004-01, Vol.43 (2), p.560-568

2004

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Structural Basis for the Recognition of Oxidized Phospholipids in Oxidized Low Density Lipoproteins by Class B Scavenger Receptors CD36 and SR-BI

The Journal of biological chemistry, 2010-02, Vol.285 (7), p.4447-4454

2010

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Analysis of relationship between oxidized phospholipid structure and interaction with the class B scavenger receptors

Methods in molecular biology (Clifton, N.J.), 2015, Vol.1208, p.29

2015

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Chemical Nature of Stochastic Generation of Protein-based Carbonyls: Metal-catalyzed Oxidation versus Modification by Products of Lipid Oxidation

Chemical research in toxicology, 2007-01, Vol.20 (1), p.129-139

2007

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Catabolism of 4-Hydroxyacids and 4-Hydroxynonenal via 4-Hydroxy-4-phosphoacyl-CoAs

The Journal of biological chemistry, 2009-11, Vol.284 (48), p.33521-33534

2009

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Long-Lived 4-Oxo-2-enal-Derived Apparent Lysine Michael Adducts Are Actually the Isomeric 4-Ketoamides

Chemical research in toxicology, 2007-02, Vol.20 (2), p.165-170

2007

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How important is oxidative damage? Lessons from Alzheimer’s disease

Free radical biology & medicine, 2000-03, Vol.28 (5), p.831-834

2000

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Mass Spectrometric Characterization of Protein Modification by the Products of Nonenzymatic Oxidation of Linoleic Acid

Chemical research in toxicology, 2009-08, Vol.22 (8), p.1386-1397

2009

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Is oxidative damage the fundamental pathogenic mechanism of Alzheimer’s and other neurodegenerative diseases?

Free Radical Biology and Medicine, 2002-12, Vol.33 (11), p.1475-1479

2002

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Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease

Methods in molecular biology (Clifton, N.J.), 2010, Vol.610, p.419

2010

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Covalent Cross-Linking of Glutathione and Carnosine to Proteins by 4-Oxo-2-nonenal

Chemical research in toxicology, 2009-06, Vol.22 (6), p.1050-1059

2009

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A mass spectrometric analysis of 4-hydroxy-2-(E)-nonenal modification of cytochrome c

Journal of mass spectrometry., 2011-03, Vol.46 (3), p.290-297

2011

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Synthesis of Six Epoxyketooctadecenoic Acid (EKODE) Isomers, Their Generation from Nonenzymatic Oxidation of Linoleic Acid, and Their Reactivity with Imidazole Nucleophiles

Journal of organic chemistry, 2007-12, Vol.72 (25), p.9471-9480

2007

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Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations

Free radical biology & medicine, 2005-03, Vol.38 (6), p.746-754

2005

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Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans

Neuroscience letters, 2002-02, Vol.319 (1), p.25-28

2002

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Mass Spectroscopic Characterization of Protein Modification by 4-Hydroxy-2-(E)-nonenal and 4-Oxo-2-(E)-nonenal

Chemical research in toxicology, 2003-07, Vol.16 (7), p.901-911

2003

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Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover

Free radical biology & medicine, 2012-02, Vol.52 (3), p.699-704

2012

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Metal ions and oxidative protein modification in neurological disease

Annali dell'Istituto superiore di sanità, 2005, Vol.41 (2), p.143

2005

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Discovery of a Sensitive, Selective, and Tightly Binding Fluorogenic Substrate of Bovine Plasma Amine Oxidase

Journal of organic chemistry, 2009-01, Vol.74 (1), p.339-350

2009

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Oxidative Stress and Neurotoxicity

Protein Adducts Generated from Products of Lipid Oxidation: Focus on HNE and ONE

Chemistry and biochemistry of oxidative stress in neurodegenerative disease

4-Oxo-2-nonenal Is Both More Neurotoxic and More Protein Reactive than 4-Hydroxy-2-nonenal

Iron Accumulation in Alzheimer Disease is a Source of Redox-Generated Free Radicals

Widespread Peroxynitrite-Mediated Damage in Alzheimer's Disease

Copper Mediates Dityrosine Cross-Linking of Alzheimer's Amyloid-β

Structural Basis for the Recognition of Oxidized Phospholipids in Oxidized Low Density Lipoproteins by Class B Scavenger Receptors CD36 and SR-BI

Analysis of relationship between oxidized phospholipid structure and interaction with the class B scavenger receptors

Chemical Nature of Stochastic Generation of Protein-based Carbonyls: Metal-catalyzed Oxidation versus Modification by Products of Lipid Oxidation

Catabolism of 4-Hydroxyacids and 4-Hydroxynonenal via 4-Hydroxy-4-phosphoacyl-CoAs

Long-Lived 4-Oxo-2-enal-Derived Apparent Lysine Michael Adducts Are Actually the Isomeric 4-Ketoamides

How important is oxidative damage? Lessons from Alzheimer’s disease

Mass Spectrometric Characterization of Protein Modification by the Products of Nonenzymatic Oxidation of Linoleic Acid

Is oxidative damage the fundamental pathogenic mechanism of Alzheimer’s and other neurodegenerative diseases?

Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease

Covalent Cross-Linking of Glutathione and Carnosine to Proteins by 4-Oxo-2-nonenal

A mass spectrometric analysis of 4-hydroxy-2-(E)-nonenal modification of cytochrome c

Synthesis of Six Epoxyketooctadecenoic Acid (EKODE) Isomers, Their Generation from Nonenzymatic Oxidation of Linoleic Acid, and Their Reactivity with Imidazole Nucleophiles

Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations

Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans

Mass Spectroscopic Characterization of Protein Modification by 4-Hydroxy-2-(E)-nonenal and 4-Oxo-2-(E)-nonenal

Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover

Metal ions and oxidative protein modification in neurological disease

Discovery of a Sensitive, Selective, and Tightly Binding Fluorogenic Substrate of Bovine Plasma Amine Oxidase

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