UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 105

Sortiert nach

Janus-kinase-2 relates directly to portal hypertension and to complications in rodent and human cirrhosis

Gut, 2017-01, Vol.66 (1), p.145

2017

Link zum Volltext

Verfügbarkeit prüfen

Conditional deletion of Jak2 reveals an essential role in hematopoiesis throughout mouse ontogeny: implications for Jak2 inhibition in humans

PloS one, 2013-03, Vol.8 (3), p.e59675

2013

Link zum Volltext

Verfügbarkeit prüfen

The Jak2 small molecule inhibitor, G6, reduces the tumorigenic potential of T98G glioblastoma cells in vitro and in vivo

PloS one, 2014-08, Vol.9 (8), p.e105568-e105568

2014

Link zum Volltext

Verfügbarkeit prüfen

Vascular smooth muscle Jak2 deletion prevents angiotensin II-mediated neointima formation following injury in mice

Journal of molecular and cellular cardiology, 2011-06, Vol.50 (6), p.1026-1034

2011

Link zum Volltext

Verfügbarkeit prüfen

Vascular smooth muscle Jak2 mediates angiotensin II-induced hypertension via increased levels of reactive oxygen species

Cardiovascular research, 2011-07, Vol.91 (1), p.171-179

2011

Link zum Volltext

Verfügbarkeit prüfen

Jak2 Tyrosine Kinase Mediates Oxidative Stress-induced Apoptosis in Vascular Smooth Muscle Cells

The Journal of biological chemistry, 2004-08, Vol.279 (33), p.34547-34552

2004

Link zum Volltext

Verfügbarkeit prüfen

The Constitutive Activation of Jak2-V617F Is Mediated by a π Stacking Mechanism Involving Phenylalanines 595 and 617

Biochemistry (Easton), 2010-11, Vol.49 (46), p.9972-9984

2010

Link zum Volltext

Verfügbarkeit prüfen

Angiotensin II mediates cell survival through upregulation and activation of the serum and glucocorticoid inducible kinase 1

Cellular signalling, 2012-02, Vol.24 (2), p.435-442

2012

Link zum Volltext

Verfügbarkeit prüfen

ERK1/2 regulates ANG II-dependent cell proliferation via cytoplasmic activation of RSK2 and nuclear activation of elk1

American Journal of Physiology: Cell Physiology, 2006-12, Vol.291 (6), p.C1308-C1317

2006

Link zum Volltext

Verfügbarkeit prüfen

Hemodynamic regulator and mitogenic growth factor: Re-visiting the age old question with ACE2 and Jak2

Regulatory peptides, 2014-02, Vol.189, p.v-vi

Sayeski, Peter P.

2014

Link zum Volltext

Verfügbarkeit prüfen

Jak2 Tyrosine Kinase: A Potential Therapeutic Target for AT1 Receptor Mediated Cardiovascular Disease

Pharmaceuticals, 2010-11, Vol.3 (11), p.3478-3493

2010

Link zum Volltext

Verfügbarkeit prüfen

The Jak2 Inhibitor, G6, Alleviates Jak2-V617F – Mediated Myeloproliferative Neoplasia by Providing Significant Therapeutic Efficacy to the Bone Marrow

Neoplasia (New York, N.Y.), 2011-11, Vol.13 (11), p.1058-1068

2011

Link zum Volltext

Verfügbarkeit prüfen

Z3, a novel Jak2 tyrosine kinase small-molecule inhibitor that suppresses Jak2-mediated pathologic cell growth

Molecular cancer therapeutics, 2008-08, Vol.7 (8), p.2308-2318

2008

Link zum Volltext

Verfügbarkeit prüfen

Identification of Tyrosine 972 as a Novel Site of Jak2 Tyrosine Kinase Phosphorylation and Its Role in Jak2 Activation

Biochemistry (Easton), 2008-08, Vol.47 (32), p.8326-8334

2008

Link zum Volltext

Verfügbarkeit prüfen

Identification of myeloproliferative neoplasm drug agents via predictive simulation modeling: assessing responsiveness with micro-environment derived cytokines

Oncotarget, 2016-06, Vol.7 (24), p.35989-36001

2016

Link zum Volltext

Verfügbarkeit prüfen

Elevated levels of mast cells are involved in pruritus associated with polycythemia vera in JAK2V617F transgenic mice

The Journal of immunology (1950), 2014-07, Vol.193 (2), p.477-484

2014

Link zum Volltext

Verfügbarkeit prüfen

Jak2 Tyrosine Kinase Mediates Angiotensin II-dependent Inactivation of ERK2 via Induction of Mitogen-activated Protein Kinase Phosphatase 1

The Journal of biological chemistry, 2004-01, Vol.279 (3), p.1956-1967

2004

Link zum Volltext

Verfügbarkeit prüfen

Identification of Tubulin as a Substrate of Jak2 Tyrosine Kinase and Its Role in Jak2-Dependent Signaling

Biochemistry (Easton), 2007-06, Vol.46 (24), p.7153-7162

2007

Link zum Volltext

Verfügbarkeit prüfen

A shift in the salt bridge interaction of residues D620 and E621 mediates the constitutive activation of Jak2-H538Q/K539L

Molecular and cellular biochemistry, 2012-08, Vol.367 (1-2), p.125-140

2012

Link zum Volltext

Verfügbarkeit prüfen

Identification of 8-Hydroxyquinoline Derivatives Active Against Somatic V658F Mutant JAK1-Dependent Cells

Archiv der Pharmazie (Weinheim), 2016-12, Vol.349 (12), p.925-933

2016

Link zum Volltext

Verfügbarkeit prüfen

Jak2 inhibitors: Rationale and role as therapeutic agents in hematologic malignancies

Current oncology reports, 2009-03, Vol.11 (2), p.117-124

2009

Link zum Volltext

Verfügbarkeit prüfen

Phosphorylation of Y372 is critical for Jak2 tyrosine kinase activation

Cellular signalling, 2011-11, Vol.23 (11), p.1806-1815

2011

Link zum Volltext

Verfügbarkeit prüfen

The critical role of c-Src and the Shc/Grb2/ERK2 signaling pathway in angiotensin II-dependent VSMC proliferation

Experimental cell research, 2003-07, Vol.287 (2), p.339-349

2003

Link zum Volltext

Verfügbarkeit prüfen

Recent developments on JAK2 inhibitors: a patent review

Expert opinion on therapeutic patents, 2010-04, Vol.20 (4), p.471-495

2010

Link zum Volltext

Verfügbarkeit prüfen

1 – 25 von 105

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(102)
Mit Volltextzugriff
(98)

Publikationsform

Artikel
(105)

Sprache

Englisch
(105)
Japanisch
(9)
Deutsch
(1)

Erscheinungsjahr

n.n

Thema

Science & Technology
(56)
Life Sciences & Biomedicine
(54)
Animals
(47)
Humans
(33)
Signal Transduction
(25)
Janus Kinase 2
(24)
Mice
(24)
Phosphorylation
(21)
Janus Kinase 2 - Metabolism
(19)
Janus Kinase 2 - Antagonists & Inhibitors
(18)
Janus Kinase 2 - Genetics
(18)
Biological And Medical Sciences
(16)
Biochemistry & Molecular Biology
(15)
Angiotensin Ii
(14)
Cells, Cultured
(14)
Protein Kinase Inhibitors - Pharmacology
(14)
Cell Biology
(13)
Jak2
(13)
Kinases
(12)
Protein-Tyrosine Kinases - Metabolism
(12)

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

5 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Janus-kinase-2 relates directly to portal hypertension and to complications in rodent and human cirrhosis

Conditional deletion of Jak2 reveals an essential role in hematopoiesis throughout mouse ontogeny: implications for Jak2 inhibition in humans

The Jak2 small molecule inhibitor, G6, reduces the tumorigenic potential of T98G glioblastoma cells in vitro and in vivo

Vascular smooth muscle Jak2 deletion prevents angiotensin II-mediated neointima formation following injury in mice

Vascular smooth muscle Jak2 mediates angiotensin II-induced hypertension via increased levels of reactive oxygen species

Jak2 Tyrosine Kinase Mediates Oxidative Stress-induced Apoptosis in Vascular Smooth Muscle Cells

The Constitutive Activation of Jak2-V617F Is Mediated by a π Stacking Mechanism Involving Phenylalanines 595 and 617

Angiotensin II mediates cell survival through upregulation and activation of the serum and glucocorticoid inducible kinase 1

ERK1/2 regulates ANG II-dependent cell proliferation via cytoplasmic activation of RSK2 and nuclear activation of elk1

Hemodynamic regulator and mitogenic growth factor: Re-visiting the age old question with ACE2 and Jak2

Jak2 Tyrosine Kinase: A Potential Therapeutic Target for AT1 Receptor Mediated Cardiovascular Disease

The Jak2 Inhibitor, G6, Alleviates Jak2-V617F – Mediated Myeloproliferative Neoplasia by Providing Significant Therapeutic Efficacy to the Bone Marrow

Z3, a novel Jak2 tyrosine kinase small-molecule inhibitor that suppresses Jak2-mediated pathologic cell growth

Identification of Tyrosine 972 as a Novel Site of Jak2 Tyrosine Kinase Phosphorylation and Its Role in Jak2 Activation

Identification of myeloproliferative neoplasm drug agents via predictive simulation modeling: assessing responsiveness with micro-environment derived cytokines

Elevated levels of mast cells are involved in pruritus associated with polycythemia vera in JAK2V617F transgenic mice

Jak2 Tyrosine Kinase Mediates Angiotensin II-dependent Inactivation of ERK2 via Induction of Mitogen-activated Protein Kinase Phosphatase 1

Identification of Tubulin as a Substrate of Jak2 Tyrosine Kinase and Its Role in Jak2-Dependent Signaling

Whole-exome sequencing in evaluation of patients with venous thromboembolism

A shift in the salt bridge interaction of residues D620 and E621 mediates the constitutive activation of Jak2-H538Q/K539L

Identification of 8-Hydroxyquinoline Derivatives Active Against Somatic V658F Mutant JAK1-Dependent Cells

Jak2 inhibitors: Rationale and role as therapeutic agents in hematologic malignancies

Phosphorylation of Y372 is critical for Jak2 tyrosine kinase activation

The critical role of c-Src and the Shc/Grb2/ERK2 signaling pathway in angiotensin II-dependent VSMC proliferation

Recent developments on JAK2 inhibitors: a patent review

Suchergebnisse filtern