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Targeting the extrinsic apoptosis signaling pathway for cancer therapy

Cancer Immunology, Immunotherapy, 2011-08, Vol.60 (8), p.1173-1180

Sayers, Thomas J.

2011

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NK Cells Preferentially Target Tumor Cells with a Cancer Stem Cell Phenotype

The Journal of immunology (1950), 2015-10, Vol.195 (8), p.4010-4019

2015

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Dung mimicry in Typhonium (Araceae): explaining floral trait and pollinator divergence in a widespread species complex and a rare sister species

Botanical journal of the Linnean Society, 2020-06, Vol.193 (3), p.375-401

2020

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Divergence in floral scent and morphology, but not thermogenic traits, associated with pollinator shift in two brood-site-mimicking Typhonium (Araceae) species

Annals of botany, 2021-08, Vol.128 (3), p.261-280

2021

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Increased secretory leukocyte protease inhibitor (SLPI) production by highly metastatic mouse breast cancer cells

PloS one, 2014-08, Vol.9 (8), p.e104223

2014

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Visitor or vector? The extent of rove beetle (Coleoptera: Staphylinidae) pollination and floral interactions

Arthropod-plant interactions, 2019-10, Vol.13 (5), p.685-701

2019

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Targeting of survivin by nanoliposomal ceramide induces complete remission in a rat model of NK-LGL leukemia

Blood, 2010-11, Vol.116 (20), p.4192-4201

2010

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New flow cytometric assays for monitoring cell-mediated cytotoxicity

Expert review of vaccines, 2010-06, Vol.9 (6), p.601-616

2010

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Sensitization of renal carcinoma cells to TRAIL-induced apoptosis by rocaglamide and analogs

Scientific reports, 2018-11, Vol.8 (1), p.17519-11, Article 17519

2018

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Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins

Cancer research (Chicago, Ill.), 2021-06, Vol.81 (12), p.3374-3386

2021

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Withanolides from Aeroponically Grown Physalis peruviana and Their Selective Cytotoxicity to Prostate Cancer and Renal Carcinoma Cells

Journal of natural products (Washington, D.C.), 2017-07, Vol.80 (7), p.1981-1991

2017

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Cytotoxic and other withanolides from aeroponically grown Physalis philadelphica

Phytochemistry (Oxford), 2018-08, Vol.152, p.174-181

2018

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Ring A/B-Modified 17β-Hydroxywithanolide Analogues as Antiproliferative Agents for Prostate Cancer and Potentiators of Immunotherapy for Renal Carcinoma and Melanoma

Journal of natural products (Washington, D.C.), 2021-12, Vol.84 (12), p.3029-3038

2021

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Sensitization of Tumor Cells to NK Cell-Mediated Killing by Proteasome Inhibition

The Journal of immunology (1950), 2008-01, Vol.180 (1), p.163-170

2008

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Using natural products to promote caspase-8-dependent cancer cell death

Cancer Immunology, Immunotherapy, 2017-02, Vol.66 (2), p.223-231

2017

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17β-Hydroxywithanolides as Sensitizers of Renal Carcinoma Cells to Tumor Necrosis Factor‑α Related Apoptosis Inducing Ligand (TRAIL) Mediated Apoptosis: Structure–Activity Relationships

Journal of medicinal chemistry, 2017-04, Vol.60 (7), p.3039-3051

2017

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Regulatory T cells and myeloid-derived suppressor cells in the tumor microenvironment undergo Fas-dependent cell death during IL-2/αCD40 therapy

The Journal of immunology (1950), 2014-06, Vol.192 (12), p.5821-5829

2014

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Bortezomib sensitizes human renal cell carcinomas to TRAIL apoptosis through increased activation of caspase-8 in the death-inducing signaling complex

Molecular cancer research, 2010-05, Vol.8 (5), p.729-738

2010

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Inhibition of Acute Graft-versus-Host Disease with Retention of Graft-versus-Tumor Effects by the Proteasome Inhibitor Bortezomib

Proceedings of the National Academy of Sciences - PNAS, 2004-05, Vol.101 (21), p.8120-8125

2004

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Impact of dietary components on NK and Treg cell function for cancer prevention

Molecular carcinogenesis, 2015-09, Vol.54 (9), p.669-678

2015

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Principles of stem cell biology and cancer: future applications and therapeutics.

1, 2015

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Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity

Cancer research (Chicago, Ill.), 2015-12, Vol.75 (24), p.5260-5272

2015

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The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP

Blood, 2003-07, Vol.102 (1), p.303-310

2003

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NKG2D recognition and perforin effector function mediate effective cytokine immunotherapy of cancer

The Journal of experimental medicine, 2004-11, Vol.200 (10), p.1325-1335

2004

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Clerodane Diterpenes from Casearia arguta That Act As Synergistic TRAIL Sensitizers

Journal of natural products (Washington, D.C.), 2010-12, Vol.73 (12), p.2013-2018

2010

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Targeting the extrinsic apoptosis signaling pathway for cancer therapy

NK Cells Preferentially Target Tumor Cells with a Cancer Stem Cell Phenotype

Dung mimicry in Typhonium (Araceae): explaining floral trait and pollinator divergence in a widespread species complex and a rare sister species

Divergence in floral scent and morphology, but not thermogenic traits, associated with pollinator shift in two brood-site-mimicking Typhonium (Araceae) species

Increased secretory leukocyte protease inhibitor (SLPI) production by highly metastatic mouse breast cancer cells

Visitor or vector? The extent of rove beetle (Coleoptera: Staphylinidae) pollination and floral interactions

Targeting of survivin by nanoliposomal ceramide induces complete remission in a rat model of NK-LGL leukemia

New flow cytometric assays for monitoring cell-mediated cytotoxicity

Sensitization of renal carcinoma cells to TRAIL-induced apoptosis by rocaglamide and analogs

Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins

Withanolides from Aeroponically Grown Physalis peruviana and Their Selective Cytotoxicity to Prostate Cancer and Renal Carcinoma Cells

Cytotoxic and other withanolides from aeroponically grown Physalis philadelphica

Ring A/B-Modified 17β-Hydroxywithanolide Analogues as Antiproliferative Agents for Prostate Cancer and Potentiators of Immunotherapy for Renal Carcinoma and Melanoma

Sensitization of Tumor Cells to NK Cell-Mediated Killing by Proteasome Inhibition

Using natural products to promote caspase-8-dependent cancer cell death

17β-Hydroxywithanolides as Sensitizers of Renal Carcinoma Cells to Tumor Necrosis Factor‑α Related Apoptosis Inducing Ligand (TRAIL) Mediated Apoptosis: Structure–Activity Relationships

Regulatory T cells and myeloid-derived suppressor cells in the tumor microenvironment undergo Fas-dependent cell death during IL-2/αCD40 therapy

Bortezomib sensitizes human renal cell carcinomas to TRAIL apoptosis through increased activation of caspase-8 in the death-inducing signaling complex

Inhibition of Acute Graft-versus-Host Disease with Retention of Graft-versus-Tumor Effects by the Proteasome Inhibitor Bortezomib

Impact of dietary components on NK and Treg cell function for cancer prevention

Principles of stem cell biology and cancer: future applications and therapeutics.

Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity

The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP

NKG2D recognition and perforin effector function mediate effective cytokine immunotherapy of cancer

Clerodane Diterpenes from Casearia arguta That Act As Synergistic TRAIL Sensitizers

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