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Bacteriophages: Perspectives and Future

Savva, Renos

2020

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The Essential Co-Option of Uracil-DNA Glycosylases by Herpesviruses Invites Novel Antiviral Design

Microorganisms (Basel), 2020-03, Vol.8 (3), p.461

Savva, Renos

2020

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A Multimodal Approach towards Genomic Identification of Protein Inhibitors of Uracil-DNA Glycosylase

Viruses, 2023-06, Vol.15 (6), p.1348

2023

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Cryo-EM Structures of Two Bacteriophage Portal Proteins Provide Insights for Antimicrobial Phage Engineering

Viruses, 2021-12, Vol.13 (12), p.2532

2021

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Targeting uracil-DNA glycosylases for therapeutic outcomes using insights from virus evolution

Future medicinal chemistry, 2019-06, Vol.11 (11), p.1323-1344

Savva, Renos

2019

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Engineering human MEK-1 for structural studies: A case study of combinatorial domain hunting

Journal of structural biology, 2012-02, Vol.177 (2), p.329-334

2012

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A Comparative Study of Uracil-DNA Glycosylases from Human and Herpes Simplex Virus Type 1

The Journal of biological chemistry, 2006-02, Vol.281 (8), p.4983-4992

2006

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The structural basis of specific base-excision repair by uracil-DNA glycosylase

Nature (London), 1995-02, Vol.373 (6514), p.487-493

1995

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A structurally conserved motif in γ-herpesvirus uracil-DNA glycosylases elicits duplex nucleotide-flipping

Nucleic acids research, 2018-05, Vol.46 (8), p.4286

2018

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Solving the riddle of codon usage preferences: a test for translational selection

Nucleic acids research, 2004-01, Vol.32 (17), p.5036

2004

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Unexpected correlations between gene expression and codon usage bias from microarray data for the whole Escherichia coli K-12 genome

Nucleic acids research, 2003-12, Vol.31 (23), p.6976

2003

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Direct Measurement of the Substrate Preference of Uracil-DNA Glycosylase

The Journal of biological chemistry, 1998-01, Vol.273 (1), p.45-50

1998

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Crystal structure of a KSHV-SOX-DNA complex: insights into the molecular mechanisms underlying DNase activity and host shutoff

Nucleic acids research, 2011-07, Vol.39 (13), p.5744

2011

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Architecturally diverse proteins converge on an analogous mechanism to inactivate Uracil-DNA glycosylase

Nucleic acids research, 2013-10, Vol.41 (18), p.8760

2013

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DNA fragmentation-based combinatorial approaches to soluble protein expression Part I. Generating DNA fragment libraries

Drug discovery today, 2007-11, Vol.12 (21-22), p.931-938

2007

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DNA fragmentation based combinatorial approaches to soluble protein expression Part II: Library expression, screening and scale-up

Drug discovery today, 2007-11, Vol.12 (21-22), p.939-947

2007

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A structural and functional dissection of the cardiac stress response factor MS1

Proteins, structure, function, and bioinformatics, 2012-02, Vol.80 (2), p.398-409

2012

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Crystal Structure of a G:T/U Mismatch-Specific DNA Glycosylase: Mismatch Recognition by Complementary-Strand Interactions

Cell, 1998-01, Vol.92 (1), p.117-129

1998

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DNA fragmentation-based combinatorial approaches to soluble protein expression Part I. Generating DNA fragment librairies

Drug discovery today, 2007, Vol.12 (21-22), p.931-938

2007

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DNA fragmentation-based combinatorial approaches to soluble protein expression

Drug discovery today, 2007-11, Vol.12 (21), p.931-938

2007

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DNA fragmentation based combinatorial approaches to soluble protein expression

Drug discovery today, 2007-11, Vol.12 (21), p.939-947

2007

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Crystal structure of a thwarted mismatch glycosylase DNA repair complex

The EMBO journal, 1999-12, Vol.18 (23), p.6599-6609

1999

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Combinatorial Domain Hunting: An effective approach for the identification of soluble protein domains adaptable to high‐throughput applications

Protein science, 2006-10, Vol.15 (10), p.2356-2365

2006

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A combinatorial method to enable detailed investigation of protein-protein interactions

Future medicinal chemistry, 2011-03, Vol.3 (3), p.271-282

2011

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Nucleotide mimicry in the crystal structure of the uracil-DNA glycosylase-uracil glycosylase inhibitor protein complex

Nature structural & molecular biology, 1995-09, Vol.2 (9), p.752-757

1995

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Bacteriophages: Perspectives and Future

The Essential Co-Option of Uracil-DNA Glycosylases by Herpesviruses Invites Novel Antiviral Design

A Multimodal Approach towards Genomic Identification of Protein Inhibitors of Uracil-DNA Glycosylase

Cryo-EM Structures of Two Bacteriophage Portal Proteins Provide Insights for Antimicrobial Phage Engineering

Targeting uracil-DNA glycosylases for therapeutic outcomes using insights from virus evolution

Engineering human MEK-1 for structural studies: A case study of combinatorial domain hunting

A Comparative Study of Uracil-DNA Glycosylases from Human and Herpes Simplex Virus Type 1

The structural basis of specific base-excision repair by uracil-DNA glycosylase

A structurally conserved motif in γ-herpesvirus uracil-DNA glycosylases elicits duplex nucleotide-flipping

Solving the riddle of codon usage preferences: a test for translational selection

Unexpected correlations between gene expression and codon usage bias from microarray data for the whole Escherichia coli K-12 genome

Direct Measurement of the Substrate Preference of Uracil-DNA Glycosylase

Crystal structure of a KSHV-SOX-DNA complex: insights into the molecular mechanisms underlying DNase activity and host shutoff

Architecturally diverse proteins converge on an analogous mechanism to inactivate Uracil-DNA glycosylase

DNA fragmentation-based combinatorial approaches to soluble protein expression Part I. Generating DNA fragment libraries

DNA fragmentation based combinatorial approaches to soluble protein expression Part II: Library expression, screening and scale-up

A structural and functional dissection of the cardiac stress response factor MS1

Crystal Structure of a G:T/U Mismatch-Specific DNA Glycosylase: Mismatch Recognition by Complementary-Strand Interactions

DNA fragmentation-based combinatorial approaches to soluble protein expression Part I. Generating DNA fragment librairies

DNA fragmentation-based combinatorial approaches to soluble protein expression

DNA fragmentation based combinatorial approaches to soluble protein expression

Crystal structure of a thwarted mismatch glycosylase DNA repair complex

Combinatorial Domain Hunting: An effective approach for the identification of soluble protein domains adaptable to high‐throughput applications

A combinatorial method to enable detailed investigation of protein-protein interactions

Nucleotide mimicry in the crystal structure of the uracil-DNA glycosylase-uracil glycosylase inhibitor protein complex

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