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The Isoform Selective Roles of PI3Ks in Dendritic Cell Biology and Function

Frontiers in immunology, 2018-11, Vol.9, p.2574-2574

2018

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IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses

Nature communications, 2020-06, Vol.11 (1), p.2779-2779, Article 2779

2020

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The role of endocytic trafficking in antigen T cell receptor activation

Biomedical Journal, 2022-04, Vol.45 (2), p.310-320

2022

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IRAP Identifies an Endosomal Compartment Required for MHC Class I Cross-Presentation

Science (American Association for the Advancement of Science), 2009-07, Vol.325 (5937), p.213-217

2009

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PD-L1- and IL-4-expressing basophils promote pathogenic accumulation of T follicular helper cells in lupus

Nature communications, 2024-04, Vol.15 (1), p.3389-3389, Article 3389

2024

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Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum

Nature Immunology, 2005-07, Vol.6 (7), p.689-697

2005

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Conventional dendritic cells require IRAP-Rab14 endosomes for efficient cross-presentation

The Journal of immunology (1950), 2012-02, Vol.188 (4), p.1840-1846

2012

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Insulin-regulated aminopeptidase contributes to setting the intensity of FcR-mediated inflammation

Frontiers in immunology, 2022-10, Vol.13, p.1029759-1029759

2022

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Innate Immune Signals Induce Anterograde Endosome Transport Promoting MHC Class I Cross-Presentation

Cell reports (Cambridge), 2018-09, Vol.24 (13), p.3568-3581

2018

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Control of IFN-I responses by the aminopeptidase IRAP in neonatal C57BL/6 alveolar macrophages during RSV infection

Mucosal immunology, 2021-07, Vol.14 (4), p.949-962

2021

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The Role of Insulin Regulated Aminopeptidase in Endocytic Trafficking and Receptor Signaling in Immune Cells

Frontiers in molecular biosciences, 2020-10, Vol.7, p.583556-583556

2020

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IRAP Endosomes Control Phagosomal Maturation in Dendritic Cells

Frontiers in cell and developmental biology, 2020-12, Vol.8, p.585713-585713

2020

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Activating FcγR function depends on endosomal-signaling platforms

iScience, 2023-07, Vol.26 (7), p.107055-107055, Article 107055

2023

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The Role of Endoplasmic Reticulum-Associated Aminopeptidase 1 in Immunity to Infection and in Cross-Presentation

Journal of Immunology, 2007-02, Vol.178 (4), p.2241-2248

2007

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New pieces in the complex puzzle of aberrant vacuolation . Focus on “Active vacuolar H + ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P 2 loss under PIKfyve or Vps34 deficiency”

American Journal of Physiology: Cell Physiology, 2016-09, Vol.311 (3), p.C363-C365

2016

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New pieces in the complex puzzle of aberrant vacuolation. Focus on "Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency"

American Journal of Physiology: Cell Physiology, 2016-09, Vol.311 (3), p.C363-C365

2016

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Complexity, contradictions, and conundrums: studying post-proteasomal proteolysis in HLA class I antigen presentation

Immunological reviews, 2005-10, Vol.207 (1), p.42-59

2005

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A detailed analysis of the murine TAP transporter substrate specificity

PloS one, 2008-06, Vol.3 (6), p.e2402-e2402

2008

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M1-aminopeptidase family — beyond antigen-trimming activities

Current opinion in immunology, 2023-08, Vol.83, p.102337-102337, Article 102337

2023

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ERAP1-ERAP2 dimerization increases peptide-trimming efficiency

The Journal of immunology (1950), 2014-07, Vol.193 (2), p.901-908

2014

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A Long N-terminal-extended Nested Set of Abundant and Antigenic Major Histocompatibility Complex Class I Natural Ligands from HIV Envelope Protein

The Journal of biological chemistry, 2006-03, Vol.281 (10), p.6358-6365

2006

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Peptidases trimming MHC class I ligands

Current opinion in immunology, 2013-02, Vol.25 (1), p.90-96

2013

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Pancreatic β-Cells Limit Autoimmune Diabetes via an Immunoregulatory Antimicrobial Peptide Expressed under the Influence of the Gut Microbiota

Immunity (Cambridge, Mass.), 2015-08, Vol.43 (2), p.304-317

2015

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A proteasome-dependent, TAP-independent pathway for cross-presentation of phagocytosed antigen

EMBO reports, 2011-12, Vol.12 (12), p.1257-1264

2011

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Is there a place and role for endocytic TCR signaling?

Immunological reviews, 2019-09, Vol.291 (1), p.57-74

2019

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The Isoform Selective Roles of PI3Ks in Dendritic Cell Biology and Function

IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses

The role of endocytic trafficking in antigen T cell receptor activation

IRAP Identifies an Endosomal Compartment Required for MHC Class I Cross-Presentation

PD-L1- and IL-4-expressing basophils promote pathogenic accumulation of T follicular helper cells in lupus

Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum

Conventional dendritic cells require IRAP-Rab14 endosomes for efficient cross-presentation

Insulin-regulated aminopeptidase contributes to setting the intensity of FcR-mediated inflammation

Innate Immune Signals Induce Anterograde Endosome Transport Promoting MHC Class I Cross-Presentation

Control of IFN-I responses by the aminopeptidase IRAP in neonatal C57BL/6 alveolar macrophages during RSV infection

The Role of Insulin Regulated Aminopeptidase in Endocytic Trafficking and Receptor Signaling in Immune Cells

IRAP Endosomes Control Phagosomal Maturation in Dendritic Cells

Activating FcγR function depends on endosomal-signaling platforms

The Role of Endoplasmic Reticulum-Associated Aminopeptidase 1 in Immunity to Infection and in Cross-Presentation

New pieces in the complex puzzle of aberrant vacuolation . Focus on “Active vacuolar H + ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P 2 loss under PIKfyve or Vps34 deficiency”

New pieces in the complex puzzle of aberrant vacuolation. Focus on "Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency"

Complexity, contradictions, and conundrums: studying post-proteasomal proteolysis in HLA class I antigen presentation

A detailed analysis of the murine TAP transporter substrate specificity

M1-aminopeptidase family — beyond antigen-trimming activities

ERAP1-ERAP2 dimerization increases peptide-trimming efficiency

A Long N-terminal-extended Nested Set of Abundant and Antigenic Major Histocompatibility Complex Class I Natural Ligands from HIV Envelope Protein

Peptidases trimming MHC class I ligands

Pancreatic β-Cells Limit Autoimmune Diabetes via an Immunoregulatory Antimicrobial Peptide Expressed under the Influence of the Gut Microbiota

A proteasome-dependent, TAP-independent pathway for cross-presentation of phagocytosed antigen

Is there a place and role for endocytic TCR signaling?

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