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Cell Surface Notch Ligand DLL3 is a Therapeutic Target in Isocitrate Dehydrogenase-mutant Glioma

Clinical cancer research, 2019-02, Vol.25 (4), p.1261-1271

2019

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Transcriptomic and Protein Analysis of Small-cell Bladder Cancer (SCBC) Identifies Prognostic Biomarkers and DLL3 as a Relevant Therapeutic Target

Clinical cancer research, 2019-01, Vol.25 (1), p.210-221

2019

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miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues

Aging (Albany, NY.), 2010-07, Vol.2 (7), p.415-431

2010

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Rova-T enhances the anti-tumor activity of anti-PD1 in a murine model of small cell lung cancer with endogenous Dll3 expression

Translational oncology, 2021-01, Vol.14 (1), p.100883-100883, Article 100883

2021

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Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor

Science (American Association for the Advancement of Science), 2013-01, Vol.339 (6116), p.211-214

2013

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Destabilization of ERBB2 Transcripts by Targeting 3′ Untranslated Region Messenger RNA Associated HuR and Histone Deacetylase-6

Molecular cancer research, 2008-07, Vol.6 (7), p.1250-1258

2008

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Venetoclax Is Effective in Small-Cell Lung Cancers with High BCL-2 Expression

Clinical cancer research, 2018-01, Vol.24 (2), p.360-369

2018

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Cell biology. Stress response and aging

Science (American Association for the Advancement of Science), 2009-02, Vol.323 (5917), p.1021-1022

2009

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Delta‐Like Protein 3 Expression and Targeting in Merkel Cell Carcinoma

The oncologist (Dayton, Ohio), 2020-09, Vol.25 (9), p.810-817

2020

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The dsRNA binding protein family: critical roles, diverse cellular functions

The FASEB journal, 2003-06, Vol.17 (9), p.961-983

2003

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Ornithine decarboxylase activity in tumor cell lines correlates with sensitivity to cell death induced by histone deacetylase inhibitors

Molecular cancer therapeutics, 2006-11, Vol.5 (11), p.2777-2785

2006

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Synthesis and Comparative In Vivo Evaluation of Site-Specifically Labeled Radioimmunoconjugates for DLL3-Targeted ImmunoPET

Bioconjugate chemistry, 2021-07, Vol.32 (7), p.1255-1262

2021

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The 90- and 110-kDa Human NFAR Proteins Are Translated from Two Differentially Spliced mRNAs Encoded on Chromosome 19p13

Genomics (San Diego, Calif.), 2001-01, Vol.71 (2), p.256-259

2001

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Characterization of Two Evolutionarily Conserved, Alternatively Spliced Nuclear Phosphoproteins, NFAR-1 and -2, That Function in mRNA Processing and Interact with the Double-stranded RNA-dependent Protein Kinase, PKR

The Journal of biological chemistry, 2001-08, Vol.276 (34), p.32300-32312

2001

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Abstract 3171: Delta-like protein 3 expression in Merkel cell carcinoma

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.3171-3171

2019

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Abstract 3950: Rovalpituzumab tesirine enhances the anti-tumor efficacy of PD-1 blockade in a murine model of small cell lung cancer with endogenous Dll3 expression

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.3950-3950

2019

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An open-label study of rovalpituzumab tesirine in patients with DLL3-expressing advanced solid tumors

Journal of clinical oncology, 2017-05, Vol.35 (15_suppl), p.TPS2597-TPS2597

2017

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Abstract NT-113: SC-003, AN ANTIBODY-DRUG CONJUGATE TARGETING DIPEPTIDASE 3, EXHIBITS POTENT ANTI-TUMOR ACTIVITY IN PATIENT-DERIVED XENOGRAFT MODELS OF HIGH GRADE SEROUS OVARIAN CANCER

Clinical cancer research, 2019-11, Vol.25 (22_Supplement), p.NT-113-NT-113

2019

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Prognostic value of CD56, ASCL1, and other biomarkers in small cell bladder cancer (SCBC)

Journal of clinical oncology, 2018-02, Vol.36 (6_suppl), p.452-452

2018

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Correlation between gene expression and prognostic biomarkers in small cell bladder cancer (SCBC)

Journal of clinical oncology, 2018-05, Vol.36 (15_suppl), p.4546-4546

2018

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Molecular profiling of small cell bladder cancer (SCBC) to reveal gene expression determinants of an aggressive phenotype

Journal of clinical oncology, 2017-05, Vol.35 (15_suppl), p.4529-4529

2017

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Abstract 3093: Expression of DLL3 in metastatic melanoma, glioblastoma and high-grade extrapulmonary neuroendocrine carcinomas as potential indications for rovalpituzumab tesirine (Rova-T; SC16LD6.5), a delta-like protein 3 (DLL3)-targeted antibody drug conjugate (ADC)

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3093-3093

2017

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Stress Response and Aging

Science (American Association for the Advancement of Science), 2009-02, Vol.323 (5917), p.1021-1022

2009

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Suppression of Oxidative Stress by [beta]-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor

Science (American Association for the Advancement of Science), 2013-01, Vol.339 (6116), p.211

2013

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A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo

Cell Surface Notch Ligand DLL3 is a Therapeutic Target in Isocitrate Dehydrogenase-mutant Glioma

Transcriptomic and Protein Analysis of Small-cell Bladder Cancer (SCBC) Identifies Prognostic Biomarkers and DLL3 as a Relevant Therapeutic Target

miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues

Rova-T enhances the anti-tumor activity of anti-PD1 in a murine model of small cell lung cancer with endogenous Dll3 expression

Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor

Destabilization of ERBB2 Transcripts by Targeting 3′ Untranslated Region Messenger RNA Associated HuR and Histone Deacetylase-6

Venetoclax Is Effective in Small-Cell Lung Cancers with High BCL-2 Expression

Cell biology. Stress response and aging

Delta‐Like Protein 3 Expression and Targeting in Merkel Cell Carcinoma

The dsRNA binding protein family: critical roles, diverse cellular functions

Ornithine decarboxylase activity in tumor cell lines correlates with sensitivity to cell death induced by histone deacetylase inhibitors

Synthesis and Comparative In Vivo Evaluation of Site-Specifically Labeled Radioimmunoconjugates for DLL3-Targeted ImmunoPET

The 90- and 110-kDa Human NFAR Proteins Are Translated from Two Differentially Spliced mRNAs Encoded on Chromosome 19p13

Characterization of Two Evolutionarily Conserved, Alternatively Spliced Nuclear Phosphoproteins, NFAR-1 and -2, That Function in mRNA Processing and Interact with the Double-stranded RNA-dependent Protein Kinase, PKR

Abstract 3171: Delta-like protein 3 expression in Merkel cell carcinoma

Abstract 3950: Rovalpituzumab tesirine enhances the anti-tumor efficacy of PD-1 blockade in a murine model of small cell lung cancer with endogenous Dll3 expression

An open-label study of rovalpituzumab tesirine in patients with DLL3-expressing advanced solid tumors

Abstract NT-113: SC-003, AN ANTIBODY-DRUG CONJUGATE TARGETING DIPEPTIDASE 3, EXHIBITS POTENT ANTI-TUMOR ACTIVITY IN PATIENT-DERIVED XENOGRAFT MODELS OF HIGH GRADE SEROUS OVARIAN CANCER

Prognostic value of CD56, ASCL1, and other biomarkers in small cell bladder cancer (SCBC)

Correlation between gene expression and prognostic biomarkers in small cell bladder cancer (SCBC)

Molecular profiling of small cell bladder cancer (SCBC) to reveal gene expression determinants of an aggressive phenotype

Abstract 3093: Expression of DLL3 in metastatic melanoma, glioblastoma and high-grade extrapulmonary neuroendocrine carcinomas as potential indications for rovalpituzumab tesirine (Rova-T; SC16LD6.5), a delta-like protein 3 (DLL3)-targeted antibody drug conjugate (ADC)

Stress Response and Aging

Suppression of Oxidative Stress by [beta]-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor

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