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Evidence for the interaction of imatinib at the transport-substrate site(s) of the multidrug-resistance-linked ABC drug transporters ABCB1 (P-glycoprotein) and ABCG2

Leukemia, 2008-02, Vol.22 (2), p.445-447

2008

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Modulating immunogenicity of factor IX by fusion to an immunoglobulin Fc domain: a study using a hemophilia B mouse model

Journal of thrombosis and haemostasis, 2017-04, Vol.15 (4), p.721-734

2017

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Genetic determinants of immunogenicity to factor IX during the treatment of haemophilia B

Haemophilia : the official journal of the World Federation of Hemophilia, 2015-03, Vol.21 (2), p.210-218

2015

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Evidence for a Requirement for ATP Hydrolysis at Two Distinct Steps during a Single Turnover of the Catalytic Cycle of Human P-glycoprotein

Proceedings of the National Academy of Sciences - PNAS, 2000-03, Vol.97 (6), p.2515-2520

2000

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Characterization of the catalytic cycle of ATP hydrolysis by human P-glycoprotein. The two ATP hydrolysis events in a single catalytic cycle are kinetically similar but affect different functional outcomes

The Journal of biological chemistry, 2001-04, Vol.276 (15), p.11653-11661

2001

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Observations regarding the immunogenicity of BDD‐rFVIII derived from a mechanistic personalized medicine perspective

Journal of thrombosis and haemostasis, 2012-09, Vol.10 (9), p.1961-1965

2012

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Analysis of F9 point mutations and their correlation to severity of haemophilia B disease

Haemophilia : the official journal of the World Federation of Hemophilia, 2012-11, Vol.18 (6), p.933-940

2012

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Understanding the contribution of synonymous mutations to human disease

Nature reviews. Genetics, 2011-10, Vol.12 (10), p.683

2011

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The mechanism of action of multidrug-resistance-linked P-glycoprotein

Journal of bioenergetics and biomembranes, 2001-12, Vol.33 (6), p.481-491

2001

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Correlation between steady-state ATP hydrolysis and vanadate-induced ADP trapping in Human P-glycoprotein. Evidence for ADP release as the rate-limiting step in the catalytic cycle and its modulation by substrates

The Journal of biological chemistry, 2001-03, Vol.276 (12), p.8657-8664

2001

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Large solutes induce structural perturbations in proteins and membranes

International journal of biological macromolecules, 2001-07, Vol.29 (1), p.5-18

2001

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Osmotic perturbations induce differential movements in the core and periphery of proteins, membranes and micelles

Biophysical chemistry, 2001-05, Vol.90 (3), p.233-248

2001

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Solvent interconnectedness permits measurement of proximal as well as distant phase transitions in polymer mixtures by fluorescence

Biophysical chemistry, 2001-04, Vol.90 (2), p.147-156

2001

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Rate-limiting step in electron transport. Osmotically sensitive diffusion of quinones through voids in the bilayer

The Journal of biological chemistry, 1993-07, Vol.268 (21), p.15442-15454

1993

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Synonymous Mutations and Ribosome Stalling Can Lead to Altered Folding Pathways and Distinct Minima

Journal of molecular biology, 2008-11, Vol.383 (2), p.281-291

2008

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The Synthesis and Evaluation of a Solution Phase Indexed Combinatorial Library of Non-Natural Polyenes for Reversal of P-Glycoprotein Mediated Multidrug Resistance

Journal of organic chemistry, 2000-08, Vol.65 (16), p.4973-4983

2000

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P-glycoprotein: from genomics to mechanism

Oncogene, 2003-10, Vol.22 (47), p.7468-7485

2003

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The power of the pump: Mechanisms of action of P-glycoprotein (ABCB1)

European journal of pharmaceutical sciences, 2006-04, Vol.27 (5), p.392-400

2006

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Evidence for the Vectorial Nature of Drug (Substrate)-stimulated ATP Hydrolysis by Human P-glycoprotein

The Journal of biological chemistry, 2001-09, Vol.276 (36), p.33301-33304

2001

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Volume regulation of spermatozoa by quinine-sensitive channels

Molecular reproduction and development, 1997-04, Vol.46 (4), p.535-550

1997

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The A-loop, a novel conserved aromatic acid subdomain upstream of the Walker A motif in ABC transporters, is critical for ATP binding

FEBS letters, 2006-02, Vol.580 (4), p.1049-1055

2006

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What does a Common Channel for Electrolytes and Non-electrolytes in the Sperm Mean?

Journal of theoretical biology, 2000-10, Vol.206 (3), p.419-428

2000

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Synthesis and preliminary analysis of a P-glycoprotein-specific [ 3H]-benzophenone photoaffinity label based on (−)-stipiamide

Bioorganic & medicinal chemistry letters, 2000-10, Vol.10 (20), p.2275-2278

2000

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A novel way to spread drug resistance in tumor cells: functional intercellular transfer of P-glycoprotein (ABCB1)

Trends in pharmacological sciences (Regular ed.), 2005-08, Vol.26 (8), p.385-387

2005

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Disulfiram, an old drug with new potential therapeutic uses for human cancers and fungal infections

Molecular bioSystems, 2005-07, Vol.1 (2), p.127-134

2005

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Evidence for the interaction of imatinib at the transport-substrate site(s) of the multidrug-resistance-linked ABC drug transporters ABCB1 (P-glycoprotein) and ABCG2

Modulating immunogenicity of factor IX by fusion to an immunoglobulin Fc domain: a study using a hemophilia B mouse model

Genetic determinants of immunogenicity to factor IX during the treatment of haemophilia B

Evidence for a Requirement for ATP Hydrolysis at Two Distinct Steps during a Single Turnover of the Catalytic Cycle of Human P-glycoprotein

Characterization of the catalytic cycle of ATP hydrolysis by human P-glycoprotein. The two ATP hydrolysis events in a single catalytic cycle are kinetically similar but affect different functional outcomes

Observations regarding the immunogenicity of BDD‐rFVIII derived from a mechanistic personalized medicine perspective

Analysis of F9 point mutations and their correlation to severity of haemophilia B disease

Understanding the contribution of synonymous mutations to human disease

The mechanism of action of multidrug-resistance-linked P-glycoprotein

Correlation between steady-state ATP hydrolysis and vanadate-induced ADP trapping in Human P-glycoprotein. Evidence for ADP release as the rate-limiting step in the catalytic cycle and its modulation by substrates

Large solutes induce structural perturbations in proteins and membranes

Osmotic perturbations induce differential movements in the core and periphery of proteins, membranes and micelles

Solvent interconnectedness permits measurement of proximal as well as distant phase transitions in polymer mixtures by fluorescence

Rate-limiting step in electron transport. Osmotically sensitive diffusion of quinones through voids in the bilayer

Synonymous Mutations and Ribosome Stalling Can Lead to Altered Folding Pathways and Distinct Minima

The Synthesis and Evaluation of a Solution Phase Indexed Combinatorial Library of Non-Natural Polyenes for Reversal of P-Glycoprotein Mediated Multidrug Resistance

P-glycoprotein: from genomics to mechanism

The power of the pump: Mechanisms of action of P-glycoprotein (ABCB1)

Evidence for the Vectorial Nature of Drug (Substrate)-stimulated ATP Hydrolysis by Human P-glycoprotein

Volume regulation of spermatozoa by quinine-sensitive channels

The A-loop, a novel conserved aromatic acid subdomain upstream of the Walker A motif in ABC transporters, is critical for ATP binding

What does a Common Channel for Electrolytes and Non-electrolytes in the Sperm Mean?

Synthesis and preliminary analysis of a P-glycoprotein-specific [ 3H]-benzophenone photoaffinity label based on (−)-stipiamide

A novel way to spread drug resistance in tumor cells: functional intercellular transfer of P-glycoprotein (ABCB1)

Disulfiram, an old drug with new potential therapeutic uses for human cancers and fungal infections

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