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DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome

ACS chemical biology, 2019-01, Vol.14 (1), p.37-49

2019

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Assessment of AI-Based Protein Structure Prediction for the NLRP3 Target

Molecules (Basel, Switzerland), 2022-09, Vol.27 (18), p.5797

2022

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What Do You Get from DNA-Encoded Libraries?

ACS medicinal chemistry letters, 2018-05, Vol.9 (5), p.408-410

Satz, Alexander L

2018

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Simulated Screens of DNA Encoded Libraries: The Potential Influence of Chemical Synthesis Fidelity on Interpretation of Structure–Activity Relationships

ACS combinatorial science, 2016-07, Vol.18 (7), p.415-424

Satz, Alexander L.

2016

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DNA Encoded Library Selections and Insights Provided by Computational Simulations

ACS chemical biology, 2015-10, Vol.10 (10), p.2237-2245

Satz, Alexander L

2015

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Selections and screenings of DNA-encoded chemical libraries against enzyme and cellular targets

Bioorganic & medicinal chemistry letters, 2021-05, Vol.39, p.127851-127851, Article 127851

2021

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Discovery of SARS-CoV-2 main protease covalent inhibitors from a DNA-encoded library selection

SLAS discovery, 2022-03, Vol.27 (2), p.79-85

2022

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Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase

Journal of medicinal chemistry, 2016-08, Vol.59 (15), p.7299-7304

2016

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Development of DNA-Compatible Van Leusen Three-Component Imidazole Synthesis

Organic letters, 2019-11, Vol.21 (22), p.9001-9004

2019

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High-Throughput Solid-Phase Building Block Synthesis for DNA-Encoded Libraries

Organic letters, 2019-12, Vol.21 (23), p.9353-9357

2019

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Analysis of Current DNA Encoded Library Screening Data Indicates Higher False Negative Rates for Numerically Larger Libraries

ACS combinatorial science, 2017-04, Vol.19 (4), p.234-238

2017

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Solution-Phase DNA-Compatible Pictet-Spengler Reaction Aided by Machine Learning Building Block Filtering

iScience, 2020-06, Vol.23 (6), p.101142, Article 101142

2020

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Synthesis of 1,2-Amino Alcohols by Photoredox-Mediated Decarboxylative Coupling of α‑Amino Acids and DNA-Conjugated Carbonyls

Organic letters, 2020-12, Vol.22 (24), p.9484-9489

2020

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Analysis of the productivity of DNA encoded libraries

MedChemComm, 2016-01, Vol.7 (7), p.1323-1331

2016

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Activity-Based DNA-Encoded Library Screening

ACS combinatorial science, 2019-05, Vol.21 (5), p.425-435

2019

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Triaging of DNA-Encoded Library Selection Results by High-Throughput Resynthesis of DNA–Conjugate and Affinity Selection Mass Spectrometry

Bioconjugate chemistry, 2021-05, Vol.32 (5), p.1001-1007

2021

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Palladium-mediated Suzuki-Miyaura Cross-Coupling Reaction of Potassium Boc-protected aminomethyltrifluoroborate with DNA-Conjugated aryl bromides for DNA-Encoded chemical library synthesis

Biochemical and biophysical research communications, 2020-12, Vol.533 (2), p.209-214

2020

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Copper-Mediated DNA-Compatible One-Pot Click Reactions of Alkynes with Aryl Borates and TMS-N 3

Organic letters, 2020-06, Vol.22 (11), p.4146-4150

2020

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Discovery of a Highly Selective BET BD2 Inhibitor from a DNA-Encoded Library Technology Screening Hit

Journal of medicinal chemistry, 2021-08, Vol.64 (15), p.10806-10833

2021

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Off-DNA DNA-Encoded Library Affinity Screening

ACS combinatorial science, 2020-01, Vol.22 (1), p.25-34

2020

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Copper-Mediated DNA-Compatible One-Pot Click Reactions of Alkynes with Aryl Borates and TMS-N3

Organic letters, 2020-06, Vol.22 (11), p.4146-4150

2020

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DNA-Compatible Copper-Catalyzed Oxidative Amidation of Aldehydes with Non-Nucleophilic Arylamines

Bioconjugate chemistry, 2020-09, Vol.31 (9), p.2092-2097

2020

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DNA‐Compatible Click Reaction Employing In Situ Generated Azides from Boronic Acids

Current protocols, 2021-05, Vol.1 (5), p.e125-n/a

2021

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DNA-Encoded Macrocyclic Peptide Libraries Enable the Discovery of a Neutral MDM2–p53 Inhibitor

ACS medicinal chemistry letters, 2023-06, Vol.14 (6), p.820-826

2023

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DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome

Assessment of AI-Based Protein Structure Prediction for the NLRP3 Target

What Do You Get from DNA-Encoded Libraries?

Simulated Screens of DNA Encoded Libraries: The Potential Influence of Chemical Synthesis Fidelity on Interpretation of Structure–Activity Relationships

DNA Encoded Library Selections and Insights Provided by Computational Simulations

Selections and screenings of DNA-encoded chemical libraries against enzyme and cellular targets

Discovery of SARS-CoV-2 main protease covalent inhibitors from a DNA-encoded library selection

Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase

Development of DNA-Compatible Van Leusen Three-Component Imidazole Synthesis

High-Throughput Solid-Phase Building Block Synthesis for DNA-Encoded Libraries

Analysis of Current DNA Encoded Library Screening Data Indicates Higher False Negative Rates for Numerically Larger Libraries

Solution-Phase DNA-Compatible Pictet-Spengler Reaction Aided by Machine Learning Building Block Filtering

Synthesis of 1,2-Amino Alcohols by Photoredox-Mediated Decarboxylative Coupling of α‑Amino Acids and DNA-Conjugated Carbonyls

Analysis of the productivity of DNA encoded libraries

Activity-Based DNA-Encoded Library Screening

Triaging of DNA-Encoded Library Selection Results by High-Throughput Resynthesis of DNA–Conjugate and Affinity Selection Mass Spectrometry

Palladium-mediated Suzuki-Miyaura Cross-Coupling Reaction of Potassium Boc-protected aminomethyltrifluoroborate with DNA-Conjugated aryl bromides for DNA-Encoded chemical library synthesis

Copper-Mediated DNA-Compatible One-Pot Click Reactions of Alkynes with Aryl Borates and TMS-N 3

Discovery of a Highly Selective BET BD2 Inhibitor from a DNA-Encoded Library Technology Screening Hit

Off-DNA DNA-Encoded Library Affinity Screening

Copper-Mediated DNA-Compatible One-Pot Click Reactions of Alkynes with Aryl Borates and TMS-N3

DNA-Compatible Copper-Catalyzed Oxidative Amidation of Aldehydes with Non-Nucleophilic Arylamines

DNA‐Compatible Click Reaction Employing In Situ Generated Azides from Boronic Acids

DNA-Encoded Macrocyclic Peptide Libraries Enable the Discovery of a Neutral MDM2–p53 Inhibitor

Discovery, SAR, and X‑ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library

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