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The Kynurenine Pathway Modulates Neurodegeneration in a Drosophila Model of Huntington's Disease

Current biology, 2011-06, Vol.21 (11), p.961-966

2011

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The Probiotic Lactobacillus reuteri Preferentially Synthesizes Kynurenic Acid from Kynurenine

International journal of molecular sciences, 2024-04, Vol.25 (7), p.3679

2024

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Tryptophan-2,3-dioxygenase (TDO) inhibition ameliorates neurodegeneration by modulation of kynurenine pathway metabolites

Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (19), p.5435-5440

2016

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Tryptophan challenge in individuals with schizophrenia and healthy controls: acute effects on circulating kynurenine and kynurenic acid, cognition and cerebral blood flow

Neuropsychopharmacology (New York, N.Y.), 2023-10, Vol.48 (11), p.1594-1601

2023

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Tryptophan Challenge in Healthy Controls and People with Schizophrenia: Acute Effects on Plasma Levels of Kynurenine, Kynurenic Acid and 5-Hydroxyindoleacetic Acid

Pharmaceuticals (Basel, Switzerland), 2022-08, Vol.15 (8), p.1003

2022

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Kynurenine 3-Monooxygenase Interacts with Huntingtin at the Outer Mitochondrial Membrane

Biomedicines, 2022-09, Vol.10 (9), p.2294

2022

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Cellular Localization of Kynurenine 3-Monooxygenase in the Brain: Challenging the Dogma

Antioxidants, 2022-02, Vol.11 (2), p.315

2022

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Crystal Structure-Based Selective Targeting of the Pyridoxal 5′-Phosphate Dependent Enzyme Kynurenine Aminotransferase II for Cognitive Enhancement

Journal of medicinal chemistry, 2010-08, Vol.53 (15), p.5684-5689

2010

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Subchronic N -acetylcysteine Treatment Decreases Brain Kynurenic Acid Levels and Improves Cognitive Performance in Mice

Antioxidants, 2021-01, Vol.10 (2), p.147

2021

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Of mice, rats and men: Revisiting the quinolinic acid hypothesis of Huntington's disease

Progress in neurobiology, 2010-02, Vol.90 (2), p.230-245

2010

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Impaired Kynurenine Pathway Metabolism in The Prefrontal Cortex of Individuals With Schizophrenia

Schizophrenia bulletin, 2011-11, Vol.37 (6), p.1147-1156

2011

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Tryptophan 2,3-dioxygenase and indoleamine 2,3-dioxygenase 1 make separate, tissue-specific contributions to basal and inflammation-induced kynurenine pathway metabolism in mice

Biochimica et biophysica acta, 2016-11, Vol.1860 (11), p.2345-2354

2016

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Targeted deletion of kynurenine 3-monooxygenase in mice: a new tool for studying kynurenine pathway metabolism in periphery and brain

The Journal of biological chemistry, 2013-12, Vol.288 (51), p.36554-36566

2013

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Maternal genotype determines kynurenic acid levels in the fetal brain: Implications for the pathophysiology of schizophrenia

Journal of psychopharmacology (Oxford), 2018-11, Vol.32 (11), p.1223-1232

2018

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Drosophila eye color mutants as therapeutic tools for Huntington disease

Fly (Austin, Tex.), 2012-04, Vol.6 (2), p.117-120

2012

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Dysfunctional kynurenine pathway metabolism in the R6/2 mouse model of Huntington's disease

Journal of neurochemistry, 2010-06, Vol.113 (6), p.1416-1425

2010

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Assessing and Modulating Kynurenine Pathway Dynamics in Huntington's Disease: Focus on Kynurenine 3-Monooxygenase

Methods in molecular biology (Clifton, N.J.), 2018, Vol.1780, p.397

2018

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The Role of Thyroid Hormones as Inductors of Oxidative Stress and Neurodegeneration

Oxidative medicine and cellular longevity, 2013-01, Vol.2013, p.218145-15

2013

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Kynurenines with Neuroactive and Redox Properties: Relevance to Aging and Brain Diseases

Oxidative medicine and cellular longevity, 2014-01, Vol.2014, p.646909-22

2014

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Thioredoxin System Regulation in the Central Nervous System: Experimental Models and Clinical Evidence

Oxidative medicine and cellular longevity, 2014-01, Vol.2014, p.590808-13

2014

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The Probiotic ILactobacillus reuteri/I Preferentially Synthesizes Kynurenic Acid from Kynurenine

International journal of molecular sciences, 2024-04, Vol.25 (7)

2024

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Brain-Specific Superoxide Dismutase 2 Deficiency Causes Perinatal Death with Spongiform Encephalopathy in Mice

Oxidative medicine and cellular longevity, 2015-01, Vol.2015, p.238914-10

2015

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Redox Status and Aging Link in Neurodegenerative Diseases

Oxidative medicine and cellular longevity, 2014-01, Vol.2014, p.270291-2

2014

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Redox Status and Aging Link in Neurodegenerative Diseases 2015

Oxidative medicine and cellular longevity, 2015-01, Vol.2015, p.494316-2

2015

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The Kynurenine Pathway Modulates Neurodegeneration in a Drosophila Model of Huntington's Disease

Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration

The Probiotic Lactobacillus reuteri Preferentially Synthesizes Kynurenic Acid from Kynurenine

Tryptophan-2,3-dioxygenase (TDO) inhibition ameliorates neurodegeneration by modulation of kynurenine pathway metabolites

Tryptophan challenge in individuals with schizophrenia and healthy controls: acute effects on circulating kynurenine and kynurenic acid, cognition and cerebral blood flow

Tryptophan Challenge in Healthy Controls and People with Schizophrenia: Acute Effects on Plasma Levels of Kynurenine, Kynurenic Acid and 5-Hydroxyindoleacetic Acid

Kynurenine 3-Monooxygenase Interacts with Huntingtin at the Outer Mitochondrial Membrane

Cellular Localization of Kynurenine 3-Monooxygenase in the Brain: Challenging the Dogma

Crystal Structure-Based Selective Targeting of the Pyridoxal 5′-Phosphate Dependent Enzyme Kynurenine Aminotransferase II for Cognitive Enhancement

Subchronic N -acetylcysteine Treatment Decreases Brain Kynurenic Acid Levels and Improves Cognitive Performance in Mice

Of mice, rats and men: Revisiting the quinolinic acid hypothesis of Huntington's disease

Impaired Kynurenine Pathway Metabolism in The Prefrontal Cortex of Individuals With Schizophrenia

Tryptophan 2,3-dioxygenase and indoleamine 2,3-dioxygenase 1 make separate, tissue-specific contributions to basal and inflammation-induced kynurenine pathway metabolism in mice

Targeted deletion of kynurenine 3-monooxygenase in mice: a new tool for studying kynurenine pathway metabolism in periphery and brain

Maternal genotype determines kynurenic acid levels in the fetal brain: Implications for the pathophysiology of schizophrenia

Drosophila eye color mutants as therapeutic tools for Huntington disease

Dysfunctional kynurenine pathway metabolism in the R6/2 mouse model of Huntington's disease

Assessing and Modulating Kynurenine Pathway Dynamics in Huntington's Disease: Focus on Kynurenine 3-Monooxygenase

The Role of Thyroid Hormones as Inductors of Oxidative Stress and Neurodegeneration

Kynurenines with Neuroactive and Redox Properties: Relevance to Aging and Brain Diseases

Thioredoxin System Regulation in the Central Nervous System: Experimental Models and Clinical Evidence

The Probiotic ILactobacillus reuteri/I Preferentially Synthesizes Kynurenic Acid from Kynurenine

Brain-Specific Superoxide Dismutase 2 Deficiency Causes Perinatal Death with Spongiform Encephalopathy in Mice

Redox Status and Aging Link in Neurodegenerative Diseases

Redox Status and Aging Link in Neurodegenerative Diseases 2015

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