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2'-O-(2-Methoxy)ethyl-modified anti-intercellular adhesion molecule 1 (ICAM-1) oligonucleotides selectively increase the ICAM-1 mRNA level and inhibit formation of the ICAM-1 translation initiation complex in human umbilical vein endothelial cells

The Journal of biological chemistry, 1997-05, Vol.272 (18), p.11994-12000

1997

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Oligonucleotide-europium complex conjugate designed to cleave the 5' cap structure of the ICAM-1 transcript potentiates antisense activity in cells

Nucleic acids research, 1999-03, Vol.27 (6), p.1547

1999

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Pharmacokinetic properties of several novel oligonucleotide analogs in mice

The Journal of pharmacology and experimental therapeutics, 1996-05, Vol.277 (2), p.923

1996

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Specific binding of lac repressor to linear versus circular polyoperator molecules

Biochemistry (Easton), 1990-09, Vol.29 (38), p.9023-9028

1990

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2â²-O-(2-Methoxy)ethyl-modified Anti-intercellular Adhesion Molecule 1 (ICAM-1) Oligonucleotides Selectively Increase the ICAM-1 mRNA Level and Inhibit Formation of the ICAM-1 Translation Initiation Complex in Human Umbilical Vein Endothelial Cells

The Journal of biological chemistry, 1997-05, Vol.272 (18), p.11994

1997

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Symmetric lac operator derivatives: effects of half-operator sequence and spacing on repressor affinity

Gene, 1990-04, Vol.89 (1), p.1-6

1990

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A practical method for the synthesis and purification of 14 C labeled oligonucleotides

Journal of labelled compounds & radiopharmaceuticals, 1995-01, Vol.36 (1), p.15-31

1995

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Base substitution mutants of the lac operator: in vivo and in vitro affinities for lac repressor

Gene, 1986, Vol.50 (1), p.123-132

1986

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A practical method for the synthesis and purification of 14C labeled oligonucleotides

Journal of labelled compounds & radiopharmaceuticals, 1995-01, Vol.36 (1), p.15-31

1995

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Positive and negative geotaxis: Sex-linked traits inDrosophila pseudoobscura

Behavior genetics, 1978-01, Vol.8 (1), p.65-71

1978

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Positive and negative geotaxis: sex-linked traits in Drosophila pseudoobscura

Behavior genetics, 1978-01, Vol.8 (1), p.65-71

1978

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A cell-free expression and purification process for rapid production of protein biologics

Biotechnology journal, 2016-02, Vol.11 (2), p.238-248

2016

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Pharmacokinetic properties of 2'-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats

The Journal of pharmacology and experimental therapeutics, 2001-03, Vol.296 (3), p.890

2001

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Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression

The Journal of biological chemistry, 1999-01, Vol.274 (3), p.1715-1722

1999

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Sequence-Specific Antitumor Activity of a Phosphorothioate Oligodeoxyribonucleotide Targeted to Human C-Raf Kinase Supports an Antisense Mechanism of Action in vivo

Proceedings of the National Academy of Sciences - PNAS, 1996-12, Vol.93 (26), p.15481-15484

1996

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Measurement of Macromolecular Binding Using Electrospray Mass Spectrometry. Determination of Dissociation Constants for Oligonucleotide: Serum Albumin Complexes

Journal of the American Chemical Society, 1995-11, Vol.117 (43), p.10765-10766

1995

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Antisense oligonucleotide inhibition of hepatitis C virus gene expression in transformed hepatocytes

Journal of Virology, 1996-08, Vol.70 (8), p.5203-5212

1996

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Absolute bioavailability of 2'-O-(2-methoxyethyl)-modified antisense oligonucleotides following intraduodenal instillation in rats

The Journal of pharmacology and experimental therapeutics, 2001-03, Vol.296 (3), p.898

2001

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Oligodeoxynucleotides containing 2'-O-modified adenosine: Synthesis and effects on stability of DNA:RNA duplexes

Biochemistry (Easton), 1993-08, Vol.32 (30), p.7832-7838

1993

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Targeted Site-Specific Gas-Phase Cleavage of Oligoribonucleotides. Application in Mass Spectrometry-Based Identification of Ligand Binding Sites

Journal of the American Chemical Society, 1999-01, Vol.121 (2), p.474-475

1999

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Antisense oligodeoxynucleotides: synthesis, biophysical and biological evaluation of oligodeoxynucleotides containing modified pyrimidines

Nucleic acids research, 1993-07, Vol.21 (14), p.3197-3203

1993

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Synthesis, hybridization, and nuclease resistance properties of 2′-O-aminooxyethyl ( 2′-O-AOE) modified oligonucleotides

Tetrahedron letters, 1999-01, Vol.40 (4), p.661-664

1999

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Antisense oligonucleotides targeting human protein kinase C-alpha inhibit phorbol ester-induced reduction of bradykinin-evoked calcium mobilization in A549 cells

Molecular pharmacology, 1997-02, Vol.51 (2), p.209-216

1997

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Oligonucleotide charge states in negative ionization electrospray-mass spectrometry are a function of solution ammonium ion concentration

Journal of the American Society for Mass Spectrometry, 1997-02, Vol.8 (2), p.155-160

1997

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Pharmacokinetics in mice of a [3H]-labeled phosphorothioate oligonucleotide formulated in the presence and absence of a cationic lipid

Journal of controlled release, 1996-08, Vol.41 (1-2), p.121-130

1996

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2'-O-(2-Methoxy)ethyl-modified anti-intercellular adhesion molecule 1 (ICAM-1) oligonucleotides selectively increase the ICAM-1 mRNA level and inhibit formation of the ICAM-1 translation initiation complex in human umbilical vein endothelial cells

Oligonucleotide-europium complex conjugate designed to cleave the 5' cap structure of the ICAM-1 transcript potentiates antisense activity in cells

Pharmacokinetic properties of several novel oligonucleotide analogs in mice

Specific binding of lac repressor to linear versus circular polyoperator molecules

2â²-O-(2-Methoxy)ethyl-modified Anti-intercellular Adhesion Molecule 1 (ICAM-1) Oligonucleotides Selectively Increase the ICAM-1 mRNA Level and Inhibit Formation of the ICAM-1 Translation Initiation Complex in Human Umbilical Vein Endothelial Cells

Symmetric lac operator derivatives: effects of half-operator sequence and spacing on repressor affinity

A practical method for the synthesis and purification of 14 C labeled oligonucleotides

Base substitution mutants of the lac operator: in vivo and in vitro affinities for lac repressor

A practical method for the synthesis and purification of 14C labeled oligonucleotides

Positive and negative geotaxis: Sex-linked traits inDrosophila pseudoobscura

Positive and negative geotaxis: sex-linked traits in Drosophila pseudoobscura

A cell-free expression and purification process for rapid production of protein biologics

Pharmacokinetic properties of 2'-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats

Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression

Sequence-Specific Antitumor Activity of a Phosphorothioate Oligodeoxyribonucleotide Targeted to Human C-Raf Kinase Supports an Antisense Mechanism of Action in vivo

Measurement of Macromolecular Binding Using Electrospray Mass Spectrometry. Determination of Dissociation Constants for Oligonucleotide: Serum Albumin Complexes

Antisense oligonucleotide inhibition of hepatitis C virus gene expression in transformed hepatocytes

Absolute bioavailability of 2'-O-(2-methoxyethyl)-modified antisense oligonucleotides following intraduodenal instillation in rats

Oligodeoxynucleotides containing 2'-O-modified adenosine: Synthesis and effects on stability of DNA:RNA duplexes

Targeted Site-Specific Gas-Phase Cleavage of Oligoribonucleotides. Application in Mass Spectrometry-Based Identification of Ligand Binding Sites

Antisense oligodeoxynucleotides: synthesis, biophysical and biological evaluation of oligodeoxynucleotides containing modified pyrimidines

Synthesis, hybridization, and nuclease resistance properties of 2′-O-aminooxyethyl ( 2′-O-AOE) modified oligonucleotides

Antisense oligonucleotides targeting human protein kinase C-alpha inhibit phorbol ester-induced reduction of bradykinin-evoked calcium mobilization in A549 cells

Oligonucleotide charge states in negative ionization electrospray-mass spectrometry are a function of solution ammonium ion concentration

Pharmacokinetics in mice of a [3H]-labeled phosphorothioate oligonucleotide formulated in the presence and absence of a cationic lipid

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