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Hedgehog Signal and Genetic Disorders

Frontiers in genetics, 2019-11, Vol.10, p.1103

2019

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Neural Progenitors Adopt Specific Identities by Directly Repressing All Alternative Progenitor Transcriptional Programs

Developmental cell, 2016-03, Vol.36 (6), p.639-653

2016

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Integration of signals along orthogonal axes of the vertebrate neural tube controls progenitor competence and increases cell diversity

PLoS biology, 2014-07, Vol.12 (7), p.e1001907-e1001907

2014

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Neural induction: Historical views and application to pluripotent stem cells

Development, growth & differentiation, 2021-01, Vol.63 (1), p.26-37

2021

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Gene Regulatory Logic for Reading the Sonic Hedgehog Signaling Gradient in the Vertebrate Neural Tube

Cell, 2012-01, Vol.148 (1-2), p.273-284

2012

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Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened

PLoS biology, 2011-06, Vol.9 (6), p.e1001083-e1001083

2011

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Manipulation of Signal Gradient and Transcription Factors Recapitulates: Multiple Hypothalamic Identities

Stem cells (Dayton, Ohio), 2023-05, Vol.41 (5), p.453-467

2023

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Negative Regulation of mTOR Signaling Restricts Cell Proliferation in the Floor Plate

Frontiers in neuroscience, 2019-09, Vol.13, p.1022-1022

2019

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Neural crest determination by co-activation of Pax3 and Zic1 genes in Xenopus ectoderm

Development (Cambridge), 2005-05, Vol.132 (10), p.2355-2363

2005

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Primary cilia and graded Sonic Hedgehog signaling

Wiley interdisciplinary reviews. Developmental biology, 2012-09, Vol.1 (5), p.753-772

2012

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Apical accumulation of Rho in the neural plate is important for neural plate cell shape change and neural tube formation

Molecular biology of the cell, 2008-05, Vol.19 (5), p.2289-2299

2008

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Dynamic assignment and maintenance of positional identity in the ventral neural tube by the morphogen sonic hedgehog

PLoS biology, 2010-06, Vol.8 (6), p.e1000382-e1000382

2010

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Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube

Genes & development, 2010-06, Vol.24 (11), p.1186-1200

2010

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Generation of Rx+/ Pax6+ Neural Retinal Precursors from Embryonic Stem Cells

Proceedings of the National Academy of Sciences - PNAS, 2005-08, Vol.102 (32), p.11331-11336

2005

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Oral Administration of Incense Resin (Styrax benzoin) Extract Enhances Spatial Learning, Memory, and Dendrite Complexity of Mice

Brazilian Archives of Biology and Technology, 2020, Vol.63

2020

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Autosomal-Dominant Corneal Endothelial Dystrophies CHED1 and PPCD1 Are Allelic Disorders Caused by Non-coding Mutations in the Promoter of OVOL2

American journal of human genetics, 2016-01, Vol.98 (1), p.75-89

2016

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Requirement of FoxD3-class signaling for neural crest determination in Xenopus

Development (Cambridge), 2001-07, Vol.128 (13), p.2525-2536

2001

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Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis

Development (Cambridge), 2006-11, Vol.133 (22), p.4463-4473

2006

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Prominin-1 Modulates Rho/ROCK-Mediated Membrane Morphology and Calcium-Dependent Intracellular Chloride Flux

Scientific reports, 2019-11, Vol.9 (1), p.15911-13, Article 15911

2019

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Early manifestations and differential gene expression associated with photoreceptor degeneration in Prom1-deficient retina

Disease models & mechanisms, 2021-11, Vol.14 (11)

2021

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Prominin‐1 deletion results in spermatogenic impairment, sperm morphological defects, and infertility in mice

Reproductive medicine and biology, 2023-01, Vol.22 (1), p.e12514-n/a

2023

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Acquisition of neural fate by combination of BMP blockade and chromatin modification

iScience, 2023-11, Vol.26 (11), p.108257, Article 108257

2023

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Control of neural crest induction by MarvelD3-mediated attenuation of JNK signalling

Scientific reports, 2018-01, Vol.8 (1), p.1204-15, Article 1204

2018

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Acquisition of neural fate by combination of BMP blockade and chromatin modification

iScience, 2023-10, Vol.26 (10), p.107887-107887, Article 107887

2023

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Hedgehog Signal and Genetic Disorders

Neural Progenitors Adopt Specific Identities by Directly Repressing All Alternative Progenitor Transcriptional Programs

Integration of signals along orthogonal axes of the vertebrate neural tube controls progenitor competence and increases cell diversity

Neural induction: Historical views and application to pluripotent stem cells

Gene Regulatory Logic for Reading the Sonic Hedgehog Signaling Gradient in the Vertebrate Neural Tube

Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened

Manipulation of Signal Gradient and Transcription Factors Recapitulates: Multiple Hypothalamic Identities

Negative Regulation of mTOR Signaling Restricts Cell Proliferation in the Floor Plate

Neural crest determination by co-activation of Pax3 and Zic1 genes in Xenopus ectoderm

Primary cilia and graded Sonic Hedgehog signaling

Apical accumulation of Rho in the neural plate is important for neural plate cell shape change and neural tube formation

Dynamic assignment and maintenance of positional identity in the ventral neural tube by the morphogen sonic hedgehog

Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube

Generation of Rx+/ Pax6+ Neural Retinal Precursors from Embryonic Stem Cells

Oral Administration of Incense Resin (Styrax benzoin) Extract Enhances Spatial Learning, Memory, and Dendrite Complexity of Mice

Autosomal-Dominant Corneal Endothelial Dystrophies CHED1 and PPCD1 Are Allelic Disorders Caused by Non-coding Mutations in the Promoter of OVOL2

Requirement of FoxD3-class signaling for neural crest determination in Xenopus

Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis

Prominin-1 Modulates Rho/ROCK-Mediated Membrane Morphology and Calcium-Dependent Intracellular Chloride Flux

Early manifestations and differential gene expression associated with photoreceptor degeneration in Prom1-deficient retina

Prominin‐1 deletion results in spermatogenic impairment, sperm morphological defects, and infertility in mice

Acquisition of neural fate by combination of BMP blockade and chromatin modification

Control of neural crest induction by MarvelD3-mediated attenuation of JNK signalling

Acquisition of neural fate by combination of BMP blockade and chromatin modification

Two Secreted Proteoglycans, Activators of Urothelial Cell-Cell Adhesion, Negatively Contribute to Bladder Cancer Initiation and Progression

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