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AMG 193, a Clinical Stage MTA-Cooperative PRMT5 Inhibitor, Drives Antitumor Activity Preclinically and in Patients with MTAP-Deleted Cancers

Cancer discovery, 2024-09, p.OF1-OF23

2024

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Abstract B177: The discovery and preclinical characterization of AMG 193, a first-in-class MTA-cooperative PRMT5 inhibitor with broad activity against MTAP -null cancers

Molecular cancer therapeutics, 2023-12, Vol.22 (12_Supplement), p.B177-B177

2023

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Novel, cyclic and bicyclic 1,3-diols as catalysts for the diethylzinc addition to aldehydes

Perkin 1 : an international journal of organic and bio-organic chemistry, 2002-02 (5), p.645-651

2002

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Asymmetric Reduction of Ketones with Catecholborane Using 2,6-BODOL Complexes of Titanium(IV) as Catalysts

Chemistry : a European journal, 2001-05, Vol.7 (10), p.2158-2166

2001

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Abstract 1807: The discovery and preclinical characterization of the MTA cooperative PRMT5 inhibitor AM-9747

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.1807-1807

2022

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Bicyclo[2.2.2]octane-derived chiral ligands—synthesis and application of BODOLs in the asymmetric reduction of acetophenone with catecholborane

Tetrahedron: asymmetry, 2008-08, Vol.19 (15), p.1765-1777

2008

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improved stereoselective reduction of a bicyclic diketone by Saccharomyces cerevisiae combining process optimization and strain engineering

Applied microbiology and biotechnology, 2002-09, Vol.59 (6), p.641-648

2002

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Structure Investigation of Ti IV ‐BODOLates Involved in the Catalytic Asymmetric Reduction of Ketones Using Catecholborane

Chemistry : a European journal, 2004-01, Vol.10 (1), p.182-189

2004

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Structure Investigation of TiIV-BODOLates Involved in the Catalytic Asymmetric Reduction of Ketones Using Catecholborane

Chemistry : a European journal, 2004-01, Vol.10 (1), p.182-189

2004

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Self-assembly of chiral bicyclic keto-alcohols into supramolecular helices in the solid state

CrystEngComm, 2002, Vol.4 (26), p.146

2002

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Screening of yeast species for the stereo-selective reduction of bicyclo[2.2.2]octane-2,6-dione

Perkin 1 : an international journal of organic and bio-organic chemistry, 2002-01 (8), p.1111-1114

2002

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Synthetic studies towards pseudopterosin A

Journal of the Chemical Society, Perkin Transactions 1, 1996-02 (4), p.303

1996

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ChemInform Abstract: Novel, Cyclic and Bicyclic 1,3-Diols as Catalysts for the Diethylzinc Addition to Aldehydes

ChemInform, 2002-07, Vol.33 (30), p.no-no

2002

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ChemInform Abstract: Asymmetric Reduction of Ketones with Catecholborane Using 2,6-BODOL Complexes of Titanium(IV) as Catalysts

ChemInform, 2002-04, Vol.33 (13), p.no-no

2002

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Screening of Yeast Species for the Stereoselective Reduction of Bicyclo[2.2.2]octane-2,6-dione

ChemInform, 2002-09, Vol.33 (35), p.79-79

2002

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AMG 193, a Clinical Stage MTA-Cooperative PRMT5 Inhibitor, Drives Antitumor Activity Preclinically and in Patients with MTAP-Deleted Cancers

Abstract B177: The discovery and preclinical characterization of AMG 193, a first-in-class MTA-cooperative PRMT5 inhibitor with broad activity against MTAP -null cancers

Novel, cyclic and bicyclic 1,3-diols as catalysts for the diethylzinc addition to aldehydes

Asymmetric Reduction of Ketones with Catecholborane Using 2,6-BODOL Complexes of Titanium(IV) as Catalysts

Abstract 1807: The discovery and preclinical characterization of the MTA cooperative PRMT5 inhibitor AM-9747

Bicyclo[2.2.2]octane-derived chiral ligands—synthesis and application of BODOLs in the asymmetric reduction of acetophenone with catecholborane

improved stereoselective reduction of a bicyclic diketone by Saccharomyces cerevisiae combining process optimization and strain engineering

Structure Investigation of Ti IV ‐BODOLates Involved in the Catalytic Asymmetric Reduction of Ketones Using Catecholborane

Structure Investigation of TiIV-BODOLates Involved in the Catalytic Asymmetric Reduction of Ketones Using Catecholborane

Self-assembly of chiral bicyclic keto-alcohols into supramolecular helices in the solid state

Screening of yeast species for the stereo-selective reduction of bicyclo[2.2.2]octane-2,6-dione

Synthetic studies towards pseudopterosin A

ChemInform Abstract: Novel, Cyclic and Bicyclic 1,3-Diols as Catalysts for the Diethylzinc Addition to Aldehydes

ChemInform Abstract: Asymmetric Reduction of Ketones with Catecholborane Using 2,6-BODOL Complexes of Titanium(IV) as Catalysts

Screening of Yeast Species for the Stereoselective Reduction of Bicyclo[2.2.2]octane-2,6-dione

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