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Improving drug delivery to primary and metastatic brain tumors: Strategies to overcome the blood-brain barrier

Clinical pharmacology and therapeutics, 2015-04, Vol.97 (4), p.336-346

2015

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EGFRvIII stimulates glioma growth and invasion through PKA-dependent serine phosphorylation of Dock180

Oncogene, 2014-05, Vol.33 (19), p.2504-2512

2014

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Oncolytic measles virus strains have significant antitumor activity against glioma stem cells

Gene therapy, 2013-04, Vol.20 (4), p.444-449

2013

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A role for ATR in the DNA damage-induced phosphorylation of p53

Genes & development, 1999-01, Vol.13 (2), p.152-157

1999

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Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine

Cancer research (Chicago, Ill.), 1999-09, Vol.59 (17), p.4375-4382

1999

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Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent Wortmannin

Cancer research (Chicago, Ill.), 1998-10, Vol.58 (19), p.4375-4382

1998

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p53 isoform profiling in glioblastoma and injured brain

Oncogene, 2013-06, Vol.32 (26), p.3165-3174

2013

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High-dose-rate versus low-dose-rate brachytherapy in the treatment of cervical cancer: analysis of tumor recurrence—the University of Wisconsin experience

International journal of radiation oncology, biology, physics, 1999-12, Vol.45 (5), p.1267-1274

1999

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The adverse effect of treatment prolongation in cervical carcinoma

International journal of radiation oncology, biology, physics, 1995-07, Vol.32 (5), p.1301-1307

1995

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Spatially graded hydrogels for preclinical testing of glioblastoma anticancer therapeutics

MRS communications, 2017-09, Vol.7 (3), p.442-449

2017

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Oral tongue cancer in young adults less than 40 years of age: Rationale for aggressive therapy

Head & neck, 1994-03, Vol.16 (2), p.107-111

1994

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Disruption of Parallel and Converging Signaling Pathways Contributes to the Synergistic Antitumor Effects of Simultaneous mTOR and EGFR Inhibition in GBM Cells

Neoplasia (New York, N.Y.), 2005-10, Vol.7 (10), p.921-929

2005

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Protein kinase A-dependent phosphorylation of Dock180 at serine residue 1250 is important for glioma growth and invasion stimulated by platelet derived-growth factor receptor

Neuro-oncology (Charlottesville, Va.), 2015-06, Vol.17 (6), p.832-842

2015

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Biopsy validation of 18F-DOPA PET and biodistribution in gliomas for neurosurgical planning and radiotherapy target delineation: results of a prospective pilot study

Neuro-oncology (Charlottesville, Va.), 2013-08, Vol.15 (8), p.1058-1067

2013

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Comparison between pulsed-field gel electrophoresis and the comet assay as predictive assays for radiosensitivity in fibroblasts

Radiation research, 1998-07, Vol.150 (1), p.17

1998

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Perioperative morbidity and mortality of high-dose-rate gynecologic brachytherapy

International journal of radiation oncology, biology, physics, 1998-12, Vol.42 (5), p.1025-1031

1998

Volltextzugriff (PDF)

p16-Cdk4-Rb axis controls sensitivity to a cyclin-dependent kinase inhibitor PD0332991 in glioblastoma xenograft cells

Neuro-oncology (Charlottesville, Va.), 2012-07, Vol.14 (7), p.870-881

2012

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ATM as a target for novel radiosensitizers

Seminars in radiation oncology, 2001-10, Vol.11 (4), p.316-327

2001

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Factors Influencing the Central Nervous System Distribution of a Novel Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitor GSK2126458: Implications for Overcoming Resistance with Combination Therapy for Melanoma Brain Metastases

The Journal of pharmacology and experimental therapeutics, 2016-02, Vol.356 (2), p.251

2016

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Decreased affinity for efflux transporters increases brain penetrance and molecular targeting of a PI3K/mTOR inhibitor in a mouse model of glioblastoma

Neuro-oncology (Charlottesville, Va.), 2015-09, Vol.17 (9), p.1210-1219

2015

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Preclinical Characterization of AZD9574, a Blood-Brain Barrier Penetrant Inhibitor of PARP1

Clinical cancer research, 2024-04, Vol.30 (7), p.1338

2024

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A comparison of the efficacy and complication rates of low dose-rate versus high dose-rate brachytherapy in the treatment of uterine cervical carcinoma

International journal of radiation oncology, biology, physics, 1994-08, Vol.30 (1), p.75-82

1994

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Radiosurgery in the initial management of malignant gliomas: Survival comparison with the RTOG recursive partitioning analysis

International journal of radiation oncology, biology, physics, 1995-07, Vol.32 (4), p.931-941

1995

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4-hydroxytamoxifen, an active metabolite of tamoxifen, does not alter the radiation sensitivity of MCF-7 breast carcinoma cells irradiated in vitro

Breast cancer research and treatment, 1994, Vol.30 (2), p.159-165

1994

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Use of an Orthotopic Xenograft Model for Assessing the Effect of Epidermal Growth Factor Receptor Amplification on Glioblastoma Radiation Response

Clinical cancer research, 2006-04, Vol.12 (7), p.2264-2271

2006

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Improving drug delivery to primary and metastatic brain tumors: Strategies to overcome the blood-brain barrier

EGFRvIII stimulates glioma growth and invasion through PKA-dependent serine phosphorylation of Dock180

Oncolytic measles virus strains have significant antitumor activity against glioma stem cells

A role for ATR in the DNA damage-induced phosphorylation of p53

Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine

Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent Wortmannin

p53 isoform profiling in glioblastoma and injured brain

High-dose-rate versus low-dose-rate brachytherapy in the treatment of cervical cancer: analysis of tumor recurrence—the University of Wisconsin experience

The adverse effect of treatment prolongation in cervical carcinoma

Spatially graded hydrogels for preclinical testing of glioblastoma anticancer therapeutics

Oral tongue cancer in young adults less than 40 years of age: Rationale for aggressive therapy

Disruption of Parallel and Converging Signaling Pathways Contributes to the Synergistic Antitumor Effects of Simultaneous mTOR and EGFR Inhibition in GBM Cells

Protein kinase A-dependent phosphorylation of Dock180 at serine residue 1250 is important for glioma growth and invasion stimulated by platelet derived-growth factor receptor

Biopsy validation of 18F-DOPA PET and biodistribution in gliomas for neurosurgical planning and radiotherapy target delineation: results of a prospective pilot study

Comparison between pulsed-field gel electrophoresis and the comet assay as predictive assays for radiosensitivity in fibroblasts

Perioperative morbidity and mortality of high-dose-rate gynecologic brachytherapy

p16-Cdk4-Rb axis controls sensitivity to a cyclin-dependent kinase inhibitor PD0332991 in glioblastoma xenograft cells

ATM as a target for novel radiosensitizers

Factors Influencing the Central Nervous System Distribution of a Novel Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitor GSK2126458: Implications for Overcoming Resistance with Combination Therapy for Melanoma Brain Metastases

Decreased affinity for efflux transporters increases brain penetrance and molecular targeting of a PI3K/mTOR inhibitor in a mouse model of glioblastoma

Preclinical Characterization of AZD9574, a Blood-Brain Barrier Penetrant Inhibitor of PARP1

A comparison of the efficacy and complication rates of low dose-rate versus high dose-rate brachytherapy in the treatment of uterine cervical carcinoma

Radiosurgery in the initial management of malignant gliomas: Survival comparison with the RTOG recursive partitioning analysis

4-hydroxytamoxifen, an active metabolite of tamoxifen, does not alter the radiation sensitivity of MCF-7 breast carcinoma cells irradiated in vitro

Use of an Orthotopic Xenograft Model for Assessing the Effect of Epidermal Growth Factor Receptor Amplification on Glioblastoma Radiation Response

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