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Endo‐lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease?

Journal of neurochemistry, 2017-03, Vol.140 (5), p.703-717

2017

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Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization

Nature cell biology, 2014-11, Vol.16 (11), p.1057-1068

2014

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The mTOR–lysosome axis at the centre of ageing

FEBS open bio, 2022-04, Vol.12 (4), p.739-757

2022

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Colchicine exerts anti‐atherosclerotic and ‑plaque‐stabilizing effects targeting foam cell formation

The FASEB journal, 2023-04, Vol.37 (4), p.e22846-n/a

2023

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Lysosomal LAMP1 immunoreactivity exists in both diffuse and neuritic amyloid plaques in the human hippocampus

The European journal of neuroscience, 2018-05, Vol.47 (9), p.1043-1053

2018

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The composition of the gut microbiota following early-life antibiotic exposure affects host health and longevity in later life

Cell reports (Cambridge), 2021-08, Vol.36 (8), p.109564-109564, Article 109564

2021

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Transcriptional targets of senataxin and E2 promoter binding factors are associated with neuro-degenerative pathways during increased autophagic flux

Scientific reports, 2022-10, Vol.12 (1), p.17665-17665, Article 17665

2022

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Gut Microbiome Regulation of Autophagic Flux and Neurodegenerative Disease Risks

Frontiers in microbiology, 2021-12, Vol.12, p.817433-817433

2021

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Human monocyte-derived microglia-like cell models: A review of the benefits, limitations and recommendations

Brain, behavior, and immunity, 2023-01, Vol.107, p.98-109

2023

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Commentary: Possible involvement of lysosomal dysfunction in pathological changes of the brain in aged progranulin-deficient mice

Frontiers in aging neuroscience, 2016-02, Vol.8, p.11-11

Sargeant, Timothy J

2016

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Rapamycin and Alzheimer disease: a double-edged sword?

Autophagy, 2019-08, Vol.15 (8), p.1460-1462

2019

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Human autophagy measurement: an underappreciated barrier to translation

Trends in molecular medicine, 2021-12, Vol.27 (12), p.1091-1094

2021

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Receptor Recycling by Retromer

Molecular and cellular biology, 2023-07, Vol.43 (7), p.317-334

2023

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epHero – a tandem-fluorescent probe to track the fate of apoptotic cells during efferocytosis

Cell death discovery, 2024-04, Vol.10 (1), p.179-179, Article 179

2024

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Rapamycin and Alzheimer disease: a hypothesis for the effective use of rapamycin for treatment of neurodegenerative disease

Autophagy, 2023-08, Vol.19 (8), p.2386-2390

2023

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Reduction in open field activity in the absence of memory deficits in the AppNL−G−F knock-in mouse model of Alzheimer’s disease

Behavioural brain research, 2018-01, Vol.336, p.177-181

2018

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Retromer has a selective function in cargo sorting via endosome transport carriers

The Journal of cell biology, 2019-02, Vol.218 (2), p.615-631

2019

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Retromer dysfunction at the nexus of tauopathies

Cell death and differentiation, 2021-03, Vol.28 (3), p.884-899

2021

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Lysosomal gene Hexb displays haploinsufficiency in a knock-in mouse model of Alzheimer’s disease

IBRO neuroscience reports, 2022-06, Vol.12, p.131-141

2022

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Biological Sensing of Nitric Oxide in Macrophages and Atherosclerosis Using a Ruthenium-Based Sensor

Biomedicines, 2022-07, Vol.10 (8), p.1807

2022

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Characterization of inducible models of Tay-Sachs and related disease

PLoS genetics, 2012-09, Vol.8 (9), p.e1002943

2012

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The Break-Fast study protocol: a single arm pre-post study to measure the effect of a protein-rich breakfast on autophagic flux in fasting healthy individuals

BMC nutrition, 2022-11, Vol.8 (1), p.1-120, Article 120

2022

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Intermittent fasting plus early time-restricted eating versus calorie restriction and standard care in adults at risk of type 2 diabetes: a randomized controlled trial

Nature medicine, 2023-04, Vol.29 (4), p.963-972

2023

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A 3-D in vitro co-culture model of mammary gland involution

Integrative biology (Cambridge), 2014-01, Vol.6 (6), p.618-626

2014

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ATG8ylation of proteins: A way to cope with cell stress?

The Journal of cell biology, 2021-11, Vol.220 (11), p.1

2021

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Endo‐lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease?

Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization

The mTOR–lysosome axis at the centre of ageing

Colchicine exerts anti‐atherosclerotic and ‑plaque‐stabilizing effects targeting foam cell formation

Lysosomal LAMP1 immunoreactivity exists in both diffuse and neuritic amyloid plaques in the human hippocampus

The composition of the gut microbiota following early-life antibiotic exposure affects host health and longevity in later life

Transcriptional targets of senataxin and E2 promoter binding factors are associated with neuro-degenerative pathways during increased autophagic flux

Gut Microbiome Regulation of Autophagic Flux and Neurodegenerative Disease Risks

Human monocyte-derived microglia-like cell models: A review of the benefits, limitations and recommendations

Commentary: Possible involvement of lysosomal dysfunction in pathological changes of the brain in aged progranulin-deficient mice

Rapamycin and Alzheimer disease: a double-edged sword?

Human autophagy measurement: an underappreciated barrier to translation

Receptor Recycling by Retromer

epHero – a tandem-fluorescent probe to track the fate of apoptotic cells during efferocytosis

Rapamycin and Alzheimer disease: a hypothesis for the effective use of rapamycin for treatment of neurodegenerative disease

Reduction in open field activity in the absence of memory deficits in the AppNL−G−F knock-in mouse model of Alzheimer’s disease

Retromer has a selective function in cargo sorting via endosome transport carriers

Retromer dysfunction at the nexus of tauopathies

Lysosomal gene Hexb displays haploinsufficiency in a knock-in mouse model of Alzheimer’s disease

Biological Sensing of Nitric Oxide in Macrophages and Atherosclerosis Using a Ruthenium-Based Sensor

Characterization of inducible models of Tay-Sachs and related disease

The Break-Fast study protocol: a single arm pre-post study to measure the effect of a protein-rich breakfast on autophagic flux in fasting healthy individuals

Intermittent fasting plus early time-restricted eating versus calorie restriction and standard care in adults at risk of type 2 diabetes: a randomized controlled trial

A 3-D in vitro co-culture model of mammary gland involution

ATG8ylation of proteins: A way to cope with cell stress?

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