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Substituted dienes prepared from betulinic acid – Synthesis, cytotoxicity, mechanism of action, and pharmacological parameters

European journal of medicinal chemistry, 2021-11, Vol.224, p.113706-113706, Article 113706

2021

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Triterpenoid pyrazines and pyridines – Synthesis, cytotoxicity, mechanism of action, preparation of prodrugs

European journal of medicinal chemistry, 2022-12, Vol.243, p.114777-114777, Article 114777

2022

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Spermine amides of selected triterpenoid acids: dynamic supramolecular system formation influences the cytotoxicity of the drugs

Journal of materials chemistry. B, Materials for biology and medicine, 2020-01, Vol.8 (3), p.484-491

2020

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Pentacyclic triterpenoids with nitrogen- and sulfur-containing heterocycles: synthesis and medicinal significance

Natural product reports, 2015-09, Vol.32 (9), p.133-133

2015

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2‑Deoxyglycoside Conjugates of Lupane Triterpenoids with High Cytotoxic ActivitySynthesis, Activity, and Pharmacokinetic Profile

Bioconjugate chemistry, 2019-11, Vol.30 (11), p.2844-2858

2019

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Cytotoxic heterocyclic triterpenoids derived from betulin and betulinic acid

Bioorganic & medicinal chemistry, 2012-06, Vol.20 (11), p.3666-3674

2012

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New Lupane Derived Compounds with Pro-Apoptotic Activity in Cancer Cells: Synthesis and Structure−Activity Relationships

Journal of medicinal chemistry, 2003-12, Vol.46 (25), p.5402-5415

2003

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Pharmacological activities of natural triterpenoids and their therapeutic implications

Natural product reports, 2006-01, Vol.23 (3), p.394-411

2006

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Lupane and 18α-oleanane derivatives substituted in the position 2, their cytotoxicity and influence on cancer cells

European journal of medicinal chemistry, 2016-10, Vol.121, p.120-131

2016

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Synthesis and antiproliferative properties of new hydrophilic esters of triterpenic acids

European journal of medicinal chemistry, 2017-11, Vol.140, p.403-420

2017

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Synthesis and Evaluation of Biological Activity of the Quaternary Ammonium Salts of Lupane-, Oleanane-, and Ursane-Type Acids

Synthesis (Stuttgart), 2010-11, Vol.2010 (22), p.3839-3848

2010

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Preparation of Conjugates of Cytotoxic Lupane Triterpenes with Biotin

Bioconjugate chemistry, 2015-12, Vol.26 (12), p.2563-2570

2015

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Synthesis of cytotoxic 2,2-difluoroderivatives of dihydrobetulinic acid and allobetulin and study of their impact on cancer cells

European journal of medicinal chemistry, 2015-05, Vol.96, p.482-490

2015

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Abstract 1530: Derivatives of betulinic acid act as modulators of the androgen receptor and report cytotoxicity towards cancer cell lines

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.1530-1530

2022

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Synthesis of 3α-deuterated 7α-hydroxy-DHEA and 7-oxo-DHEA and application in LC-MS/MS plasma analysis

Steroids, 2016-08, Vol.112, p.88-94

2016

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Synthesis and Cytotoxic Activity of Triterpenoid Thiazoles Derived from Allobetulin, Methyl Betulonate, Methyl Oleanonate, and Oleanonic Acid

ChemMedChem, 2017-03, Vol.12 (5), p.390-398

2017

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Synthesis of A-Seco Derivatives of Betulinic Acid with Cytotoxic Activity

Journal of natural products (Washington, D.C.), 2004-07, Vol.67 (7), p.1100-1105

2004

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Abstract 2077: Carbonate prodrugs derived from triterpenoids with high cytotoxic activity

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.2077-2077

2016

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Synthesis of phthalates of betulinic acid and betulin with cytotoxic activity

Bioorganic & medicinal chemistry, 2005-05, Vol.13 (10), p.3447-3454

2005

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Synthesis of selectively deuterated and tritiated lupane derivatives with cytotoxic activity

Journal of radioanalytical and nuclear chemistry, 2013-11, Vol.298 (2), p.1149-1157

2013

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Triterpenoid Pyrazines and Benzopyrazines with Cytotoxic Activity

Journal of natural products (Washington, D.C.), 2007-04, Vol.70 (4), p.526-532

2007

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Biologically active triterpenoids from birch and sycamore bark

New biotechnology, 2014-07, Vol.31, p.S112-S112

2014

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super(15)N-labelled pyrazines of triterpenic acids

Journal of radioanalytical and nuclear chemistry, 2016-05, Vol.308 (2), p.733-739

2016

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15N-labelled pyrazines of triterpenic acids

Journal of radioanalytical and nuclear chemistry, 2016-05, Vol.308 (2), p.733-739

2016

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Reaction of lupane and oleanane triterpenoids with Lawesson's reagent

Tetrahedron, 2008-04, Vol.64 (17), p.3736-3743

2008

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Substituted dienes prepared from betulinic acid – Synthesis, cytotoxicity, mechanism of action, and pharmacological parameters

Triterpenoid pyrazines and pyridines – Synthesis, cytotoxicity, mechanism of action, preparation of prodrugs

Spermine amides of selected triterpenoid acids: dynamic supramolecular system formation influences the cytotoxicity of the drugs

Pentacyclic triterpenoids with nitrogen- and sulfur-containing heterocycles: synthesis and medicinal significance

2‑Deoxyglycoside Conjugates of Lupane Triterpenoids with High Cytotoxic ActivitySynthesis, Activity, and Pharmacokinetic Profile

Cytotoxic heterocyclic triterpenoids derived from betulin and betulinic acid

New Lupane Derived Compounds with Pro-Apoptotic Activity in Cancer Cells: Synthesis and Structure−Activity Relationships

Pharmacological activities of natural triterpenoids and their therapeutic implications

Lupane and 18α-oleanane derivatives substituted in the position 2, their cytotoxicity and influence on cancer cells

Synthesis and antiproliferative properties of new hydrophilic esters of triterpenic acids

Synthesis and Evaluation of Biological Activity of the Quaternary Ammonium Salts of Lupane-, Oleanane-, and Ursane-Type Acids

Preparation of Conjugates of Cytotoxic Lupane Triterpenes with Biotin

Synthesis of cytotoxic 2,2-difluoroderivatives of dihydrobetulinic acid and allobetulin and study of their impact on cancer cells

Abstract 1530: Derivatives of betulinic acid act as modulators of the androgen receptor and report cytotoxicity towards cancer cell lines

Synthesis of 3α-deuterated 7α-hydroxy-DHEA and 7-oxo-DHEA and application in LC-MS/MS plasma analysis

Synthesis and Cytotoxic Activity of Triterpenoid Thiazoles Derived from Allobetulin, Methyl Betulonate, Methyl Oleanonate, and Oleanonic Acid

Synthesis of A-Seco Derivatives of Betulinic Acid with Cytotoxic Activity

Abstract 2077: Carbonate prodrugs derived from triterpenoids with high cytotoxic activity

Synthesis of phthalates of betulinic acid and betulin with cytotoxic activity

Synthesis of selectively deuterated and tritiated lupane derivatives with cytotoxic activity

Triterpenoid Pyrazines and Benzopyrazines with Cytotoxic Activity

Biologically active triterpenoids from birch and sycamore bark

super(15)N-labelled pyrazines of triterpenic acids

15N-labelled pyrazines of triterpenic acids

Reaction of lupane and oleanane triterpenoids with Lawesson's reagent

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