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Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1

Nature (London), 2000-06, Vol.405 (6787), p.689-694

2000

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Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: A 2.2 Å resolution structure in a hexagonal crystal form

Protein science, 1998-04, Vol.7 (4), p.837-847

1998

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Presenilin 1 Is Linked with γ -Secretase Activity in the Detergent Solubilized State

Proceedings of the National Academy of Sciences - PNAS, 2000-05, Vol.97 (11), p.6138-6143

2000

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Purification and molecular characterization of cGMP-dependent protein kinase from Apicomplexan parasites. A novel chemotherapeutic target

The Journal of biological chemistry, 2002-05, Vol.277 (18), p.15913-15922

2002

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β-Secretase Cleavage at Amino Acid Residue 34 in the Amyloid β Peptide Is Dependent upon γ-Secretase Activity

The Journal of biological chemistry, 2003-06, Vol.278 (23), p.21286-21294

2003

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The Synthesis of a Prodrug of Doxorubicin Designed to Provide Reduced Systemic Toxicity and Greater Target Efficacy

Journal of medicinal chemistry, 2001-11, Vol.44 (24), p.4216-4224

2001

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Novel mutations introduced at the beta-site of amyloid beta protein precursor enhance the production of amyloid beta peptide by BACE1 in vitro and in cells

Journal of Alzheimer's disease, 2005-04, Vol.7 (2), p.139-148

2005

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ATF2 confers radiation resistance to human melanoma cells

Oncogene, 1998-01, Vol.16 (4), p.523-531

1998

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Regulation of JNK signaling by GSTp

The EMBO journal, 1999-03, Vol.18 (5), p.1321-1334

1999

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Active Human Cytomegalovirus Protease Is a Dimer (∗)

The Journal of biological chemistry, 1996-03, Vol.271 (13), p.7445-7449

1996

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Molecular cloning and functional expression of mannitol-1-phosphatase from the apicomplexan parasite Eimeria tenella

The Journal of biological chemistry, 1998-02, Vol.273 (7), p.4237-4244

1998

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Determination of the N-Terminal Amino Acid Sequence of the Purified Prothrombin from a Patient with Liver Cirrhosis

Thrombosis research, 2000-08, Vol.99 (3), p.277-283

2000

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Selective Inhibition of Factor Xa in the Prothrombinase Complex by the Carboxyl-terminal Domain of Antistasin

The Journal of biological chemistry, 1998-11, Vol.273 (46), p.30086-30091

1998

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Biochemical and Biophysical Comparison of Native and Chemically Synthesized Phospholamban and a Monomeric Phospholamban Analog (∗)

The Journal of biological chemistry, 1996-01, Vol.271 (3), p.1669-1677

1996

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The Pro Domain of β-Secretase Does Not Confer Strict Zymogen-like Properties but Does Assist Proper Folding of the Protease Domain

The Journal of biological chemistry, 2001-03, Vol.276 (13), p.10366-10373

2001

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An Uniquely Purified HCV NS3 Protease and NS4A21–34 Peptide Form a Highly Active Serine Protease Complex in Peptide Hydrolysis

Protein expression and purification, 1999-08, Vol.16 (3), p.440-447

1999

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Purification and Molecular Characterization of cGMP-dependent Protein Kinase from Apicomplexan Parasites

The Journal of biological chemistry, 2002-05, Vol.277 (18), p.15913-15922

2002

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Activity of purified hepatitis C virus protease NS3 on peptide substrates

Journal of Virology, 1996-10, Vol.70 (10), p.6694-6700

1996

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Compounds That Bind APP and Inhibit Aβ Processing in Vitro Suggest a Novel Approach to Alzheimer Disease Therapeutics

The Journal of biological chemistry, 2005-05, Vol.280 (18), p.17792-17797

2005

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Cyclopsychotride A, a Biologically Active, 31-Residue Cyclic Peptide Isolated from Psychotria longipes

Journal of natural products (Washington, D.C.), 1994-12, Vol.57 (12), p.1619-1625

1994

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Reduction of the C2 and C4 vinyl groups of Sn-protoporphyrin to form Sn-mesoporphyrin markedly enhances the ability of the metalloporphyrin to inhibit in vivo heme catabolism

Archives of biochemistry and biophysics, 1987-05, Vol.255 (1), p.64-74

1987

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A general procedure for the purification of human β-secretase expressed in Escherichia coli

Protein expression and purification, 2004-04, Vol.34 (2), p.190-196

2004

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Molecular Model of the Specificity Pocket of the Hepatitis C Virus Protease: Implications for Substrate Recognition

Proceedings of the National Academy of Sciences - PNAS, 1994-02, Vol.91 (3), p.888-892

1994

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Dual Control Mechanism for Heme Oxygenase: Tin(IV)-Protoporphyrin Potently Inhibits Enzyme Activity While Markedly Increasing Content of Enzyme Protein in Liver

Proceedings of the National Academy of Sciences - PNAS, 1987-04, Vol.84 (8), p.2464-2468

1987

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Cleavage of oligoribonucleotides by the 2',5'-oligoadenylate- dependent ribonuclease L

The Journal of biological chemistry, 1996-03, Vol.271 (9), p.4988-4992

1996

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Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1

Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: A 2.2 Å resolution structure in a hexagonal crystal form

Presenilin 1 Is Linked with γ -Secretase Activity in the Detergent Solubilized State

Purification and molecular characterization of cGMP-dependent protein kinase from Apicomplexan parasites. A novel chemotherapeutic target

β-Secretase Cleavage at Amino Acid Residue 34 in the Amyloid β Peptide Is Dependent upon γ-Secretase Activity

The Synthesis of a Prodrug of Doxorubicin Designed to Provide Reduced Systemic Toxicity and Greater Target Efficacy

Novel mutations introduced at the beta-site of amyloid beta protein precursor enhance the production of amyloid beta peptide by BACE1 in vitro and in cells

ATF2 confers radiation resistance to human melanoma cells

Regulation of JNK signaling by GSTp

Active Human Cytomegalovirus Protease Is a Dimer (∗)

Molecular cloning and functional expression of mannitol-1-phosphatase from the apicomplexan parasite Eimeria tenella

Determination of the N-Terminal Amino Acid Sequence of the Purified Prothrombin from a Patient with Liver Cirrhosis

Selective Inhibition of Factor Xa in the Prothrombinase Complex by the Carboxyl-terminal Domain of Antistasin

Biochemical and Biophysical Comparison of Native and Chemically Synthesized Phospholamban and a Monomeric Phospholamban Analog (∗)

The Pro Domain of β-Secretase Does Not Confer Strict Zymogen-like Properties but Does Assist Proper Folding of the Protease Domain

An Uniquely Purified HCV NS3 Protease and NS4A21–34 Peptide Form a Highly Active Serine Protease Complex in Peptide Hydrolysis

Purification and Molecular Characterization of cGMP-dependent Protein Kinase from Apicomplexan Parasites

Activity of purified hepatitis C virus protease NS3 on peptide substrates

Compounds That Bind APP and Inhibit Aβ Processing in Vitro Suggest a Novel Approach to Alzheimer Disease Therapeutics

Cyclopsychotride A, a Biologically Active, 31-Residue Cyclic Peptide Isolated from Psychotria longipes

Reduction of the C2 and C4 vinyl groups of Sn-protoporphyrin to form Sn-mesoporphyrin markedly enhances the ability of the metalloporphyrin to inhibit in vivo heme catabolism

A general procedure for the purification of human β-secretase expressed in Escherichia coli

Molecular Model of the Specificity Pocket of the Hepatitis C Virus Protease: Implications for Substrate Recognition

Dual Control Mechanism for Heme Oxygenase: Tin(IV)-Protoporphyrin Potently Inhibits Enzyme Activity While Markedly Increasing Content of Enzyme Protein in Liver

Cleavage of oligoribonucleotides by the 2',5'-oligoadenylate- dependent ribonuclease L

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