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Selective Excision of AZTMP by Drug-Resistant Human Immunodeficiency Virus Reverse Transcriptase

Journal of Virology, 2001-05, Vol.75 (10), p.4832-4842

2001

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Molecular Modeling and Biochemical Characterization Reveal the Mechanism of Hepatitis B Virus Polymerase Resistance to Lamivudine (3TC) and Emtricitabine (FTC)

Journal of Virology, 2001-05, Vol.75 (10), p.4771-4779

2001

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Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA

The EMBO journal, 2002-12, Vol.21 (23), p.6614-6624

2002

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Structural and biochemical basis for the difference in the helicase activity of two different constructs of SARS-CoV helicase

Cellular and molecular biology (Noisy-le-Grand, France), 2012-12, Vol.58 (1), p.114-121

2012

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Identification and characterization of coumestans as novel HCV NS5B polymerase inhibitors

Nucleic acids research, 2008-03, Vol.36 (5), p.1482-1496

2008

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Preparation of biologically active single-chain variable antibody fragments that target the HIV-1 gp120 V3 loop

Cellular and molecular biology (Noisy-le-Grand, France), 2012-12, Vol.58 (1), p.71-79

2012

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Effect of translocation defective reverse transcriptase inhibitors on the activity of N348I, a connection subdomain drug resistant HIV-1 reverse transcriptase mutant

Cellular and molecular biology (Noisy-le-Grand, France), 2012-12, Vol.58 (1), p.187-195

2012

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Taking aim at a moving target: designing drugs to inhibit drug-resistant HIV-1 reverse transcriptases

Current opinion in structural biology, 2004-12, Vol.14 (6), p.716-730

2004

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Molecular model of SARS coronavirus polymerase: implications for biochemical functions and drug design

Nucleic acids research, 2003-12, Vol.31 (24), p.7117-7130

2003

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Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA

The EMBO journal, 2001-03, Vol.20 (6), p.1449-1461

2001

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The sugar ring conformation of 4'-ethynyl-2-fluoro-2'-deoxyadenosine and its recognition by the polymerase active site of HIV reverse transcriptase

Cellular and molecular biology (Noisy-le-Grand, France), 2011-02, Vol.57 (1), p.40-46

2011

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Expression, purification, and characterization of SARS coronavirus RNA polymerase

Virology (New York, N.Y.), 2005-05, Vol.335 (2), p.165-176

2005

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Lamivudine (3TC) Resistance in HIV-1 Reverse Transcriptase Involves Steric Hindrance with β -Branched Amino Acids

Proceedings of the National Academy of Sciences - PNAS, 1999-08, Vol.96 (18), p.10027-10032

1999

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Restriction fragment mass polymorphism (RFMP) analysis based on MALDI-TOF mass spectrometry for detecting antiretroviral resistance in HIV-1 infected patients

Clinical microbiology and infection, 2013-06, Vol.19 (6), p.E263-E270

2013

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YADD Mutants of Human Immunodeficiency Virus Type 1 and Moloney Murine Leukemia Virus Reverse Transcriptase Are Resistant to Lamivudine Triphosphate (3TCTP) In Vitro

Journal of Virology, 2001-07, Vol.75 (14), p.6321-6328

2001

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Nucleoside Analog Resistance Caused by Insertions in the Fingers of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Involves ATP-Mediated Excision

Journal of Virology, 2002-09, Vol.76 (18), p.9143-9151

2002

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Nonnucleoside Reverse Transcriptase Inhibitors are Chemical Enhancers of Dimerization of the HIV Type 1 Reverse Transcriptase

Proceedings of the National Academy of Sciences - PNAS, 2001-06, Vol.98 (13), p.7188-7193

2001

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The M184V Mutation Reduces the Selective Excision of Zidovudine 5′-Monophosphate (AZTMP) by the Reverse Transcriptase of Human Immunodeficiency Virus Type 1

Journal of Virology, 2002-04, Vol.76 (7), p.3248-3256

2002

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Interactions of Conformationally Biased North and South 2‘-Fluoro-2‘,3‘-dideoxynucleoside 5‘-Triphosphates with the Active Site of HIV-1 Reverse Transcriptase

Biochemistry (Easton), 2000-09, Vol.39 (37), p.11205-11215

2000

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Structure and Function of HIV-1 Reverse Transcriptase: Molecular Mechanisms of Polymerization and Inhibition

Journal of molecular biology, 2009-01, Vol.385 (3), p.693-713

2009

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RNase H Cleavage of the 5′ End of the Human Immunodeficiency Virus Type 1 Genome

Journal of Virology, 2001-12, Vol.75 (23), p.11874-11880

2001

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A Tag‐Free Platform for Synthesis and Screening of Cyclic Peptide Libraries

Angewandte Chemie International Edition, 2024-05, Vol.63 (21), p.e202320045-n/a

International ed. in English, 2024

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Expression and purification of SARS coronavirus proteins using SUMO-fusions

Protein expression and purification, 2005-07, Vol.42 (1), p.100-110

2005

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The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase

Journal of molecular biology, 2000-07, Vol.300 (2), p.403-418

2000

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Trapping HIV-1 Reverse Transcriptase Before and After Translocation on DNA

The Journal of biological chemistry, 2003-05, Vol.278 (18), p.16280-16288

2003

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Selective Excision of AZTMP by Drug-Resistant Human Immunodeficiency Virus Reverse Transcriptase

Molecular Modeling and Biochemical Characterization Reveal the Mechanism of Hepatitis B Virus Polymerase Resistance to Lamivudine (3TC) and Emtricitabine (FTC)

Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA

Structural and biochemical basis for the difference in the helicase activity of two different constructs of SARS-CoV helicase

Identification and characterization of coumestans as novel HCV NS5B polymerase inhibitors

Preparation of biologically active single-chain variable antibody fragments that target the HIV-1 gp120 V3 loop

Effect of translocation defective reverse transcriptase inhibitors on the activity of N348I, a connection subdomain drug resistant HIV-1 reverse transcriptase mutant

Taking aim at a moving target: designing drugs to inhibit drug-resistant HIV-1 reverse transcriptases

Molecular model of SARS coronavirus polymerase: implications for biochemical functions and drug design

Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA

The sugar ring conformation of 4'-ethynyl-2-fluoro-2'-deoxyadenosine and its recognition by the polymerase active site of HIV reverse transcriptase

Expression, purification, and characterization of SARS coronavirus RNA polymerase

Lamivudine (3TC) Resistance in HIV-1 Reverse Transcriptase Involves Steric Hindrance with β -Branched Amino Acids

Restriction fragment mass polymorphism (RFMP) analysis based on MALDI-TOF mass spectrometry for detecting antiretroviral resistance in HIV-1 infected patients

YADD Mutants of Human Immunodeficiency Virus Type 1 and Moloney Murine Leukemia Virus Reverse Transcriptase Are Resistant to Lamivudine Triphosphate (3TCTP) In Vitro

Nucleoside Analog Resistance Caused by Insertions in the Fingers of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Involves ATP-Mediated Excision

Nonnucleoside Reverse Transcriptase Inhibitors are Chemical Enhancers of Dimerization of the HIV Type 1 Reverse Transcriptase

The M184V Mutation Reduces the Selective Excision of Zidovudine 5′-Monophosphate (AZTMP) by the Reverse Transcriptase of Human Immunodeficiency Virus Type 1

Interactions of Conformationally Biased North and South 2‘-Fluoro-2‘,3‘-dideoxynucleoside 5‘-Triphosphates with the Active Site of HIV-1 Reverse Transcriptase

Structure and Function of HIV-1 Reverse Transcriptase: Molecular Mechanisms of Polymerization and Inhibition

RNase H Cleavage of the 5′ End of the Human Immunodeficiency Virus Type 1 Genome

A Tag‐Free Platform for Synthesis and Screening of Cyclic Peptide Libraries

Expression and purification of SARS coronavirus proteins using SUMO-fusions

The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase

Trapping HIV-1 Reverse Transcriptase Before and After Translocation on DNA

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