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Targeting Leukemic Stem Cells in Chronic Myeloid Leukemia: Is It Worth the Effort?

International journal of molecular sciences, 2021-07, Vol.22 (13), p.7093

2021

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The Role of Hypoxic Bone Marrow Microenvironment in Acute Myeloid Leukemia and Future Therapeutic Opportunities

International journal of molecular sciences, 2021-07, Vol.22 (13), p.6857

2021

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Recent Advances in the Molecular Biology of Systemic Mastocytosis: Implications for Diagnosis, Prognosis, and Therapy

International journal of molecular sciences, 2020-06, Vol.21 (11), p.3987

2020

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Polo-like kinase-1, Aurora kinase A and WEE1 kinase are promising druggable targets in CML cells displaying BCR::ABL1-independent resistance to tyrosine kinase inhibitors

Frontiers in oncology, 2022-08, Vol.12, p.901132-901132

2022

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SYSTEMIC MASTOCYTOSIS: MOLECULAR LANDSCAPE AND IMPLICATIONS FOR TREATMENT

Mediterranean journal of hematology and infectious diseases, 2021-07, Vol.13 (1), p.e2021046-e2021046

2021

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FOXM1 Transcription Factor: A New Component of Chronic Myeloid Leukemia Stem Cell Proliferation Advantage

Journal of cellular biochemistry, 2017-11, Vol.118 (11), p.3968-3975

2017

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Combined Inhibition of Polo-Like Kinase-1 and Wee1 as a New Therapeutic Strategy to Induce Apoptotic Cell Death in Neoplastic Mast Cells

Cancers, 2022-01, Vol.14 (3), p.738

2022

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Case Report: A Novel Activating FLT3 Mutation in Acute Myeloid Leukemia

Frontiers in oncology, 2021-09, Vol.11

2021

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Prognosis in Chronic Myeloid Leukemia: Baseline Factors, Dynamic Risk Assessment and Novel Insights

Cells (Basel, Switzerland), 2023-06, Vol.12 (13), p.1703

2023

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SETD2 non genomic loss of function in advanced systemic mastocytosis is mediated by an Aurora kinase A/MDM2 axis and can be therapeutically targeted

Biomarker research, 2023-03, Vol.11 (1), p.29-29, Article 29

2023

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The applications of bacteriophages and their lysins as biocontrol agents against the foodborne pathogens Listeria monocytogenes and Campylobacter: An updated look

Veterinaria italiana, 2018-12, Vol.54 (4), p.293

2018

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Droplet digital PCR for the detection of second-generation tyrosine kinase inhibitor-resistant BCR::ABL1 kinase domain mutations in chronic myeloid leukemia

Leukemia, 2022-09, Vol.36 (9), p.2250-2260

2022

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Overcoming Resistance to Kinase Inhibitors: The Paradigm of Chronic Myeloid Leukemia

OncoTargets and therapy, 2022-01, Vol.15, p.103-116

2022

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Unstable major molecular response as a trigger for next generation sequencing‐based BCR::ABL1 mutation testing in chronic myeloid leukemia

American journal of hematology, 2024-04, Vol.99 (4), p.759-762

2024

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MPN-182 Droplet Digital PCR for Non-Invasive Detection of the KIT D816V Mutation in the Peripheral Blood of Patients With Suspected Systemic Mastocytosis

Clinical lymphoma, myeloma and leukemia, 2022-10, Vol.22 Suppl 2, p.S328

2022

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Poster: AML-269: The Anti-Leukemic Effects of the Pan-Aurora Inhibitor Tozasertib Are Negatively Influenced by Hypoxia in Acute Myeloid Leukemia

Clinical lymphoma, myeloma and leukemia, 2021-09, Vol.21, p.S215-S215

2021

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AML-269: The Anti-Leukemic Effects of the Pan-Aurora Inhibitor Tozasertib Are Negatively Influenced by Hypoxia in Acute Myeloid Leukemia

Clinical lymphoma, myeloma and leukemia, 2021-09, Vol.21, p.S297-S297

2021

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Poster: MPN-182 Droplet Digital PCR for Non-Invasive Detection of the KIT D816V Mutation in the Peripheral Blood of Patients With Suspected Systemic Mastocytosis

Clinical lymphoma, myeloma and leukemia, 2022-10, Vol.22, p.S157

2022

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Poster: CML-184 A Novel Droplet Digital PCR Strategy for Rapid and Sensitive Detection of BCR::ABL1 Kinase Domain Mutations Conferring Resistance to Second-Generation Tyrosine Kinase Inhibitors

Clinical lymphoma, myeloma and leukemia, 2022-10, Vol.22, p.S147

2022

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CML-184 A Novel Droplet Digital PCR Strategy for Rapid and Sensitive Detection of BCR::ABL1 Kinase Domain Mutations Conferring Resistance to Second-Generation Tyrosine Kinase Inhibitors

Clinical lymphoma, myeloma and leukemia, 2022-10, Vol.22, p.S289-S290

2022

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Targeting WEE1 Kinase after G2/M Checkpoint Arrest Induces Apoptosis in Chronic Myeloid Leukemia Progenitors

Blood, 2017-12, Vol.130, p.1588-1588

2017

Volltextzugriff (PDF)

Aurora Kinase a/MDM2-Mediated SETD2 Loss of Function in Chronic Myeloid Leukemia Patients in Blast Crisis Can be Therapeutically Targeted Inducing Apoptotic Cell Death in a Caspase-Dependent Way

Blood, 2019-11, Vol.134 (Supplement_1), p.4142-4142

2019

Volltextzugriff (PDF)

Ponatinib treatment in chronic myeloid leukemia cell lines targets aurora kinase A/FOXM1 axis

Hematological oncology, 2020-04, Vol.38 (2), p.201-203

2020

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Decreased bone mineral density in Costello syndrome

Molecular genetics and metabolism, 2014-01, Vol.111 (1), p.41-45

2014

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Targeting Leukemic Stem Cells in Chronic Myeloid Leukemia: Is It Worth the Effort?

The Role of Hypoxic Bone Marrow Microenvironment in Acute Myeloid Leukemia and Future Therapeutic Opportunities

Recent Advances in the Molecular Biology of Systemic Mastocytosis: Implications for Diagnosis, Prognosis, and Therapy

Polo-like kinase-1, Aurora kinase A and WEE1 kinase are promising druggable targets in CML cells displaying BCR::ABL1-independent resistance to tyrosine kinase inhibitors

SYSTEMIC MASTOCYTOSIS: MOLECULAR LANDSCAPE AND IMPLICATIONS FOR TREATMENT

FOXM1 Transcription Factor: A New Component of Chronic Myeloid Leukemia Stem Cell Proliferation Advantage

Combined Inhibition of Polo-Like Kinase-1 and Wee1 as a New Therapeutic Strategy to Induce Apoptotic Cell Death in Neoplastic Mast Cells

Case Report: A Novel Activating FLT3 Mutation in Acute Myeloid Leukemia

Prognosis in Chronic Myeloid Leukemia: Baseline Factors, Dynamic Risk Assessment and Novel Insights

SETD2 non genomic loss of function in advanced systemic mastocytosis is mediated by an Aurora kinase A/MDM2 axis and can be therapeutically targeted

The applications of bacteriophages and their lysins as biocontrol agents against the foodborne pathogens Listeria monocytogenes and Campylobacter: An updated look

Droplet digital PCR for the detection of second-generation tyrosine kinase inhibitor-resistant BCR::ABL1 kinase domain mutations in chronic myeloid leukemia

Overcoming Resistance to Kinase Inhibitors: The Paradigm of Chronic Myeloid Leukemia

Unstable major molecular response as a trigger for next generation sequencing‐based BCR::ABL1 mutation testing in chronic myeloid leukemia

MPN-182 Droplet Digital PCR for Non-Invasive Detection of the KIT D816V Mutation in the Peripheral Blood of Patients With Suspected Systemic Mastocytosis

Poster: AML-269: The Anti-Leukemic Effects of the Pan-Aurora Inhibitor Tozasertib Are Negatively Influenced by Hypoxia in Acute Myeloid Leukemia

AML-269: The Anti-Leukemic Effects of the Pan-Aurora Inhibitor Tozasertib Are Negatively Influenced by Hypoxia in Acute Myeloid Leukemia

Poster: MPN-182 Droplet Digital PCR for Non-Invasive Detection of the KIT D816V Mutation in the Peripheral Blood of Patients With Suspected Systemic Mastocytosis

Poster: CML-184 A Novel Droplet Digital PCR Strategy for Rapid and Sensitive Detection of BCR::ABL1 Kinase Domain Mutations Conferring Resistance to Second-Generation Tyrosine Kinase Inhibitors

CML-184 A Novel Droplet Digital PCR Strategy for Rapid and Sensitive Detection of BCR::ABL1 Kinase Domain Mutations Conferring Resistance to Second-Generation Tyrosine Kinase Inhibitors

Targeting WEE1 Kinase after G2/M Checkpoint Arrest Induces Apoptosis in Chronic Myeloid Leukemia Progenitors

In Systemic Masocytosis, Midostaurin Targets Both Kit and Aurora Kinase a Reverting H3K36Me3 Deficiency and Synergizes with Second-Generation Tyrosine Kinase Inhibitors

Aurora Kinase a/MDM2-Mediated SETD2 Loss of Function in Chronic Myeloid Leukemia Patients in Blast Crisis Can be Therapeutically Targeted Inducing Apoptotic Cell Death in a Caspase-Dependent Way

Ponatinib treatment in chronic myeloid leukemia cell lines targets aurora kinase A/FOXM1 axis

Decreased bone mineral density in Costello syndrome

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