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Rapid identification of a novel phosphodiesterase 7B tracer for receptor occupancy studies using LC─MS/MS

Neurochemistry international, 2020-07, Vol.137, p.104735-104735, Article 104735

2020

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A new family of H3 receptor antagonists based on the natural product Conessine

Bioorganic & medicinal chemistry letters, 2008-02, Vol.18 (4), p.1490-1494

2008

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Design and Synthesis of Novel and Selective Glycine Transporter‑1 (GlyT1) Inhibitors with Memory Enhancing Properties

Journal of medicinal chemistry, 2018-07, Vol.61 (14), p.6018-6033

2018

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Azetidine-based selective glycine transporter-1 (GlyT1) inhibitors with memory enhancing properties

Bioorganic & medicinal chemistry letters, 2020-07, Vol.30 (14), p.127214-127214, Article 127214

2020

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Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: Discovery of (R)-1-(2-(4′-(3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl)-2-methylpyrrolidine (APD916)

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (1), p.71-75

2012

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Structure-activity relationships of 3,4-dihydro-1H-quinazolin-2-one derivatives as potential CDK5 inhibitors

Bioorganic & medicinal chemistry, 2007-10, Vol.15 (20), p.6574-6595

2007

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Cyclobutenone-Based Syntheses of Polyquinanes and Bicyclo[6.3.0]undecanes by Tandem Anionic Oxy-Cope Reactions. Total Synthesis of (±)-Precapnelladiene

Journal of organic chemistry, 1998-10, Vol.63 (20), p.6905-6913

1998

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Design and evaluation of novel biphenyl sulfonamide derivatives with potent histamine H(3) receptor inverse agonist activity

Journal of medicinal chemistry, 2009-09, Vol.52 (18), p.5603

2009

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Design and Evaluation of Novel Biphenyl Sulfonamide Derivatives with Potent Histamine H3 Receptor Inverse Agonist Activity

Journal of medicinal chemistry, 2009-09, Vol.52 (18), p.5603-5611

2009

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Structure−Activity Relationships of a Series of Pyrrolo[3,2-d]pyrimidine Derivatives and Related Compounds as Neuropeptide Y5 Receptor Antagonists

Journal of medicinal chemistry, 2000-11, Vol.43 (22), p.4288-4312

2000

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Novel H3 receptor antagonists with improved pharmacokinetic profiles

Bioorganic & medicinal chemistry letters, 2008-07, Vol.18 (14), p.4133-4136

2008

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Complexation of benzamidinium by a new family of artificial receptors

Journal of the American Chemical Society, 1992-10, Vol.114 (21), p.8300-8302

1992

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Tandem Oxy-Cope-Transannular Ring Closure Route to Polyquinanes

Journal of the American Chemical Society, 1995-08, Vol.117 (32), p.8486-8487

1995

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Participation of Aromatic Groups in Oxy-Cope Reaction Sequences. Synthesis of Highly Substituted Polyquinane Ring Systems

Journal of organic chemistry, 1996-11, Vol.61 (23), p.7976-7977

1996

Volltextzugriff (PDF)

A new family of H 3 receptor antagonists based on the natural product Conessine

Bioorganic & medicinal chemistry letters, 2008-02, Vol.18 (4), p.1490-1494

2008

Volltextzugriff (PDF)

Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: Discovery of (R)-1-2-(4'-(3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl-2-methylpyrrolidine (APD916)

Bioorganic & medicinal chemistry letters, 2012, Vol.22 (1), p.71-75

2012

Volltextzugriff (PDF)

Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: Discovery of (R)-1-(2-(4&; prime; -(3-methoxypropylsulfonyl)biphenyl-4-yl)e thyl)-2-methylpyrrolidine (APD916)

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (1), p.71-75

2012

Volltextzugriff (PDF)

Design and Evaluation of Novel Biphenyl Sulfonamide Derivatives with Potent Histamine H 3 Receptor Inverse Agonist Activity

Journal of medicinal chemistry, 2009-09, Vol.52 (18), p.5603-5611

2009

Volltextzugriff (PDF)

Novel H 3 receptor antagonists with improved pharmacokinetic profiles

Bioorganic & medicinal chemistry letters, 2008-07, Vol.18 (14), p.4133-4136

2008

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Novel H sub(3) receptor antagonists with improved pharmacokinetic profiles

Bioorganic & medicinal chemistry, 2008-07, Vol.18 (14), p.4133-4136

2008

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A new family of H sub(3) receptor antagonists based on the natural product Conessine

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (4), p.1490-1494

2008

Volltextzugriff (PDF)

Structure–activity relationships of 3,4-dihydro-1 H-quinazolin-2-one derivatives as potential CDK5 inhibitors

Bioorganic & medicinal chemistry, 2007, Vol.15 (20), p.6574-6595

2007

Volltextzugriff (PDF)

Complexation of creatinine by synthetic receptors

Tetrahedron, 1995-01, Vol.51 (2), p.363-376

1995

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Discovery and evaluation of dual CDK1 and CDK2 inhibitors

Cancer research (Chicago, Ill.), 2006-04, Vol.66 (8), p.4299-4308

2006

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Rapid identification of a novel phosphodiesterase 7B tracer for receptor occupancy studies using LC─MS/MS

A new family of H3 receptor antagonists based on the natural product Conessine

Design and Synthesis of Novel and Selective Glycine Transporter‑1 (GlyT1) Inhibitors with Memory Enhancing Properties

Azetidine-based selective glycine transporter-1 (GlyT1) inhibitors with memory enhancing properties

Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: Discovery of (R)-1-(2-(4′-(3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl)-2-methylpyrrolidine (APD916)

Structure-activity relationships of 3,4-dihydro-1H-quinazolin-2-one derivatives as potential CDK5 inhibitors

Cyclobutenone-Based Syntheses of Polyquinanes and Bicyclo[6.3.0]undecanes by Tandem Anionic Oxy-Cope Reactions. Total Synthesis of (±)-Precapnelladiene

Design and evaluation of novel biphenyl sulfonamide derivatives with potent histamine H(3) receptor inverse agonist activity

Design and Evaluation of Novel Biphenyl Sulfonamide Derivatives with Potent Histamine H3 Receptor Inverse Agonist Activity

Structure−Activity Relationships of a Series of Pyrrolo[3,2-d]pyrimidine Derivatives and Related Compounds as Neuropeptide Y5 Receptor Antagonists

Novel H3 receptor antagonists with improved pharmacokinetic profiles

Complexation of benzamidinium by a new family of artificial receptors

Tandem Oxy-Cope-Transannular Ring Closure Route to Polyquinanes

Participation of Aromatic Groups in Oxy-Cope Reaction Sequences. Synthesis of Highly Substituted Polyquinane Ring Systems

A new family of H 3 receptor antagonists based on the natural product Conessine

Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: Discovery of (R)-1-2-(4'-(3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl-2-methylpyrrolidine (APD916)

Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: Discovery of (R)-1-(2-(4&; prime; -(3-methoxypropylsulfonyl)biphenyl-4-yl)e thyl)-2-methylpyrrolidine (APD916)

Design and Evaluation of Novel Biphenyl Sulfonamide Derivatives with Potent Histamine H 3 Receptor Inverse Agonist Activity

Novel H 3 receptor antagonists with improved pharmacokinetic profiles

Novel H sub(3) receptor antagonists with improved pharmacokinetic profiles

A new family of H sub(3) receptor antagonists based on the natural product Conessine

Structure–activity relationships of 3,4-dihydro-1 H-quinazolin-2-one derivatives as potential CDK5 inhibitors

Complexation of creatinine by synthetic receptors

Discovery and evaluation of dual CDK1 and CDK2 inhibitors

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