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Deletion of Chitinase-3-like 1 accelerates stroke development through enhancement of Neuroinflammation by STAT6-dependent M2 microglial inactivation in Chitinase-3-like 1 knockout mice

Experimental neurology, 2020-01, Vol.323, p.113082, Article 113082

2020

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Anti‐Chi3L1 antibody suppresses lung tumor growth and metastasis through inhibition of M2 polarization

Molecular oncology, 2022-06, Vol.16 (11), p.2214-2234

2022

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Anti‐chitinase‐3‐like 1 antibody attenuated atopic dermatitis‐like skin inflammation through inhibition of STAT3‐dependent CXCL8 expression

British journal of pharmacology, 2024-09, Vol.181 (17), p.3232-3245

2024

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K284-6111 prevents the amyloid beta-induced neuroinflammation and impairment of recognition memory through inhibition of NF-κB-mediated CHI3L1 expression

Journal of neuroinflammation, 2018-08, Vol.15 (1), p.224-13, Article 224

2018

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Inhibition of Amyloid-β (Aβ)-Induced Cognitive Impairment and Neuroinflammation in CHI3L1 Knockout Mice through Downregulation of ERK-PTX3 Pathway

International journal of molecular sciences, 2024-05, Vol.25 (10), p.5550

2024

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Presenilin‐2 knock‐In mice show severe depressive behavior via DVL3 downregulation

CNS neuroscience & therapeutics, 2024-02, Vol.30 (2), p.e14370-n/a

2024

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Inhibitory effect of punicalagin on lipopolysaccharide-induced neuroinflammation, oxidative stress and memory impairment via inhibition of nuclear factor-kappaB

Neuropharmacology, 2017-05, Vol.117, p.21-32

2017

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Antifungal drug miconazole ameliorated memory deficits in a mouse model of LPS-induced memory loss through targeting iNOS

Cell death & disease, 2020-08, Vol.11 (8), p.623, Article 623

2020

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VDUP1 Deficiency Promotes the Severity of DSS-Induced Colitis in Mice by Inducing Macrophage Infiltration

International journal of molecular sciences, 2023-09, Vol.24 (17), p.13584

2023

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MicroRNA 29a therapy for CEACAM6-expressing lung adenocarcinoma

BMC cancer, 2023-09, Vol.23 (1), p.1-843, Article 843

2023

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miR-6734 Up-Regulates p21 Gene Expression and Induces Cell Cycle Arrest and Apoptosis in Colon Cancer Cells

PloS one, 2016-08, Vol.11 (8), p.e0160961-e0160961

2016

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A small molecule targeting CHI3L1 inhibits lung metastasis by blocking IL‐13Rα2‐mediated JNK‐AP‐1 signals

Molecular oncology, 2022-01, Vol.16 (2), p.508-526

2022

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Antarctic Krill Oil Diet Protects against Lipopolysaccharide-Induced Oxidative Stress, Neuroinflammation and Cognitive Impairment

International journal of molecular sciences, 2017-11, Vol.18 (12), p.2554

2017

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Safety and tolerability of bone marrow–derived mesenchymal stem cells in lupus animal models and a phase I clinical trial in humans

Lupus, 2022-09, Vol.31 (10), p.1245-1253

2022

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Targeted Induction of Endogenous VDUP1 by Small Activating RNA Inhibits the Growth of Lung Cancer Cells

International journal of molecular sciences, 2022-07, Vol.23 (14), p.7743

2022

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Significance of chitinase-3-like protein 1 in the pathogenesis of inflammatory diseases and cancer

Experimental and Molecular Medicine, 2024, 56(0), , pp.1-18

2024

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MIR144 inhibits antimicrobial responses against Mycobacterium tuberculosis in human monocytes and macrophages by targeting the autophagy protein DRAM2

Autophagy, 2017-02, Vol.13 (2), p.423-441

2017

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K284-6111 alleviates memory impairment and neuroinflammation in Tg2576 mice by inhibition of Chitinase-3-like 1 regulating ERK-dependent PTX3 pathway

Journal of neuroinflammation, 2020-11, Vol.17 (1), p.350-350, Article 350

2020

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Design, synthesis and evaluation of novel 2-oxoindoline-based acetohydrazides as antitumor agents

Scientific reports, 2022-02, Vol.12 (1), p.2886-2886, Article 2886

2022

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Loss of parkin reduces lung tumor development by blocking p21 degradation

PloS one, 2019-05, Vol.14 (5), p.e0217037-e0217037

2019

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Effect of Isoscopoletin on Cytokine Expression in HaCaT Keratinocytes and RBL-2H3 Basophils: Preliminary Study

International journal of molecular sciences, 2024-07, Vol.25 (13), p.6908

2024

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1‐Dehydro‐[10]‐gingerdione from ginger inhibits IKKβ activity for NF‐κB activation and suppresses NF‐κB‐regulated expression of inflammatory genes

British journal of pharmacology, 2012-09, Vol.167 (1), p.128-140

2012

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CHI3L1 induces autophagy through the JNK pathway in lung cancer cells

Scientific reports, 2023-06, Vol.13 (1), p.9964-9964, Article 9964

2023

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Deficiency of parkin suppresses melanoma tumor development and metastasis through inhibition of MFN2 ubiquitination

Cancer letters, 2018-10, Vol.433, p.156-164

2018

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PRDX6 Inhibits Neurogenesis through Downregulation of WDFY1-Mediated TLR4 Signal

Molecular neurobiology, 2019-05, Vol.56 (5), p.3132-3144

2019

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Deletion of Chitinase-3-like 1 accelerates stroke development through enhancement of Neuroinflammation by STAT6-dependent M2 microglial inactivation in Chitinase-3-like 1 knockout mice

Anti‐Chi3L1 antibody suppresses lung tumor growth and metastasis through inhibition of M2 polarization

Anti‐chitinase‐3‐like 1 antibody attenuated atopic dermatitis‐like skin inflammation through inhibition of STAT3‐dependent CXCL8 expression

K284-6111 prevents the amyloid beta-induced neuroinflammation and impairment of recognition memory through inhibition of NF-κB-mediated CHI3L1 expression

Inhibition of Amyloid-β (Aβ)-Induced Cognitive Impairment and Neuroinflammation in CHI3L1 Knockout Mice through Downregulation of ERK-PTX3 Pathway

Presenilin‐2 knock‐In mice show severe depressive behavior via DVL3 downregulation

Inhibitory effect of punicalagin on lipopolysaccharide-induced neuroinflammation, oxidative stress and memory impairment via inhibition of nuclear factor-kappaB

Antifungal drug miconazole ameliorated memory deficits in a mouse model of LPS-induced memory loss through targeting iNOS

VDUP1 Deficiency Promotes the Severity of DSS-Induced Colitis in Mice by Inducing Macrophage Infiltration

MicroRNA 29a therapy for CEACAM6-expressing lung adenocarcinoma

miR-6734 Up-Regulates p21 Gene Expression and Induces Cell Cycle Arrest and Apoptosis in Colon Cancer Cells

A small molecule targeting CHI3L1 inhibits lung metastasis by blocking IL‐13Rα2‐mediated JNK‐AP‐1 signals

Antarctic Krill Oil Diet Protects against Lipopolysaccharide-Induced Oxidative Stress, Neuroinflammation and Cognitive Impairment

Safety and tolerability of bone marrow–derived mesenchymal stem cells in lupus animal models and a phase I clinical trial in humans

Targeted Induction of Endogenous VDUP1 by Small Activating RNA Inhibits the Growth of Lung Cancer Cells

Significance of chitinase-3-like protein 1 in the pathogenesis of inflammatory diseases and cancer

MIR144 inhibits antimicrobial responses against Mycobacterium tuberculosis in human monocytes and macrophages by targeting the autophagy protein DRAM2

K284-6111 alleviates memory impairment and neuroinflammation in Tg2576 mice by inhibition of Chitinase-3-like 1 regulating ERK-dependent PTX3 pathway

Design, synthesis and evaluation of novel 2-oxoindoline-based acetohydrazides as antitumor agents

Loss of parkin reduces lung tumor development by blocking p21 degradation

Effect of Isoscopoletin on Cytokine Expression in HaCaT Keratinocytes and RBL-2H3 Basophils: Preliminary Study

1‐Dehydro‐[10]‐gingerdione from ginger inhibits IKKβ activity for NF‐κB activation and suppresses NF‐κB‐regulated expression of inflammatory genes

CHI3L1 induces autophagy through the JNK pathway in lung cancer cells

Deficiency of parkin suppresses melanoma tumor development and metastasis through inhibition of MFN2 ubiquitination

PRDX6 Inhibits Neurogenesis through Downregulation of WDFY1-Mediated TLR4 Signal

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