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Regulation of RhoGEF proteins by G12/13‐coupled receptors

British journal of pharmacology, 2009-09, Vol.158 (1), p.41-49

Siehler, Sandra

2009

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Regulation of RhoGEF proteins by G 12/13 ‐coupled receptors

British journal of pharmacology, 2009-09, Vol.158 (1), p.41-49

Siehler, Sandra

2009

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High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor

PloS one, 2016-09, Vol.11 (9), p.e0163129

2016

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Reversible translocation of p115-RhoGEF by G12/13-coupled receptors

Journal of cellular biochemistry, 2008-08, Vol.104 (5), p.1660-1670

2008

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Receptor-specific regulation of ERK1/2 activation by members of the "free fatty acid receptor" family

Journal of receptors and signal transduction, 2012-08, Vol.32 (4), p.196-201

2012

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Cell-based assays in GPCR drug discovery

Biotechnology journal, 2008-04, Vol.3 (4), p.471-483

Siehler, Sandra

2008

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G12/13-dependent signaling of G-protein-coupled receptors: disease context and impact on drug discovery

Expert opinion on drug discovery, 2007-12, Vol.2 (12), p.1591-1604

Siehler, Sandra

2007

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Pharmacological profile of somatostatin and cortistatin receptors

Molecular and cellular endocrinology, 2008-05, Vol.286 (1), p.26-34

2008

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Pathways of transduction engaged by sphingosine 1-phosphate through G protein-coupled receptors

BBA - Molecular and Cell Biology of Lipids, 2002-05, Vol.1582 (1), p.94-99

2002

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Pharmacological Potentiators of TRPM5 Channel Activity

The FASEB journal, 2013-04, Vol.27 (S1)

2013

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G 12/13 -dependent signaling of G-protein-coupled receptors: disease context and impact on drug discovery

Expert opinion on drug discovery, 2007-12, Vol.2 (12), p.1591-1604

Siehler, Sandra

2007

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Muscle Nicotinic Acetylcholine Receptors containing α1‐V275 or α1‐Y233 Mutants found in a functional Screen reveal enhanced Agonist Potencies

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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Reversible translocation of p115-RhoGEF by G(12/13)-coupled receptors

Journal of cellular biochemistry, 2008-08, Vol.104 (5), p.1660-1670

2008

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Novel GPCR Screening Approach: Indirect Identification of S1P Receptor Agonists in Antagonist Screening Using a Calcium Assay

Journal of receptors and signal transduction, 2006-01, Vol.26 (5-6), p.549-575

2006

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Sphingosine 1-phosphate activates nuclear factor-kappa B through Edg receptors. Activation through Edg-3 and Edg-5, but not Edg-1, in human embryonic kidney 293 cells

The Journal of biological chemistry, 2001-12, Vol.276 (52), p.48733-48739

2001

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Novel pharmacological insights for adenylyl cyclase 5, a gatekeeper of GPCR signaling

The FASEB journal, 2010-04, Vol.24 (S1), p.lb477-lb477

2010

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HDL-like discs for assaying membrane proteins in drug discovery

Biophysical chemistry, 2012-05, Vol.165-166, p.56-61

2012

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Reversible translocation of p115‐RhoGEF by G 12/13 ‐coupled receptors

Journal of cellular biochemistry, 2008-08, Vol.104 (5), p.1660-1670

2008

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Sphingosine 1-Phosphate Activates Nuclear Factor-κB through Edg Receptors

The Journal of biological chemistry, 2001-12, Vol.276 (52), p.48733-48739

2001

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Induction of differentiation in F9 cells and activation of peroxisome proliferator-activated receptor delta by valproic acid and its teratogenic derivatives

Molecular pharmacology, 2001-05, Vol.59 (5), p.1269-1276

2001

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Characterisation of human recombinant somatostatin receptors. 1. Radioligand binding studies

Naunyn-Schmiedeberg's archives of pharmacology, 1999-11, Vol.360 (5), p.488-499

1999

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Characterisation of human recombinant somatostatin receptors. 3. Modulation of adenylate cyclase activity

Naunyn-Schmiedeberg's archives of pharmacology, 1999-11, Vol.360 (5), p.510-521

1999

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New Molecular Bioassays for the Estimation of the Teratogenic Potency of Valproic Acid Derivatives in Vitro: Activation of the Peroxisomal Proliferator-Activated Receptor (PPARδ)

Toxicology and applied pharmacology, 1999-11, Vol.160 (3), p.238-249

1999

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Characterisation of human recombinant somatostatin receptors. 4. Modulation of phospholipase C activity

Naunyn-Schmiedeberg's archives of pharmacology, 1999-11, Vol.360 (5), p.522-532

1999

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[125I][Tyr3]octreotide labels human somatostatin sst2 and sst5 receptors

European journal of pharmacology, 1998-05, Vol.348 (2-3), p.311-320

1998

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Regulation of RhoGEF proteins by G12/13‐coupled receptors

Regulation of RhoGEF proteins by G 12/13 ‐coupled receptors

High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor

Reversible translocation of p115-RhoGEF by G12/13-coupled receptors

Receptor-specific regulation of ERK1/2 activation by members of the "free fatty acid receptor" family

Cell-based assays in GPCR drug discovery

G12/13-dependent signaling of G-protein-coupled receptors: disease context and impact on drug discovery

Pharmacological profile of somatostatin and cortistatin receptors

Pathways of transduction engaged by sphingosine 1-phosphate through G protein-coupled receptors

Pharmacological Potentiators of TRPM5 Channel Activity

G 12/13 -dependent signaling of G-protein-coupled receptors: disease context and impact on drug discovery

Muscle Nicotinic Acetylcholine Receptors containing α1‐V275 or α1‐Y233 Mutants found in a functional Screen reveal enhanced Agonist Potencies

Reversible translocation of p115-RhoGEF by G(12/13)-coupled receptors

Novel GPCR Screening Approach: Indirect Identification of S1P Receptor Agonists in Antagonist Screening Using a Calcium Assay

Sphingosine 1-phosphate activates nuclear factor-kappa B through Edg receptors. Activation through Edg-3 and Edg-5, but not Edg-1, in human embryonic kidney 293 cells

Novel pharmacological insights for adenylyl cyclase 5, a gatekeeper of GPCR signaling

HDL-like discs for assaying membrane proteins in drug discovery

Reversible translocation of p115‐RhoGEF by G 12/13 ‐coupled receptors

Sphingosine 1-Phosphate Activates Nuclear Factor-κB through Edg Receptors

Induction of differentiation in F9 cells and activation of peroxisome proliferator-activated receptor delta by valproic acid and its teratogenic derivatives

Characterisation of human recombinant somatostatin receptors. 1. Radioligand binding studies

Characterisation of human recombinant somatostatin receptors. 3. Modulation of adenylate cyclase activity

New Molecular Bioassays for the Estimation of the Teratogenic Potency of Valproic Acid Derivatives in Vitro: Activation of the Peroxisomal Proliferator-Activated Receptor (PPARδ)

Characterisation of human recombinant somatostatin receptors. 4. Modulation of phospholipase C activity

[125I][Tyr3]octreotide labels human somatostatin sst2 and sst5 receptors

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