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Development of Hyperpolarized NMR Molecular Probes for Biological Applications

Bulletin of the Chemical Society of Japan, 2023-09, Vol.96 (9), p.995-1002

Sando, Shinsuke

2023

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Nongenetic Reprogramming of the Ligand Specificity of Growth Factor Receptors by Bispecific DNA Aptamers

Journal of the American Chemical Society, 2017-05, Vol.139 (19), p.6554-6557

2017

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Oligonucleotide-Based Mimetics of Hepatocyte Growth Factor

Angewandte Chemie (International ed.), 2016-01, Vol.55 (2), p.579-582

International ed. in English, 2016

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Design of Nuclear Magnetic Resonance Molecular Probes for Hyperpolarized Bioimaging

Angewandte Chemie International Edition, 2021-06, Vol.60 (27), p.14779-14799

International ed. in English, 2021

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A comprehensive study on the effect of backbone stereochemistry of a cyclic hexapeptide on membrane permeability and microsomal stability

Organic & biomolecular chemistry, 2021-12, Vol.19 (47), p.1326-1331

2021

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Design strategy for serine hydroxymethyltransferase probes based on retro-aldol-type reaction

Nature communications, 2019-02, Vol.10 (1), p.876-10, Article 876

2019

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Peptoid-based reprogrammable template for cell-permeable inhibitors of protein-protein interactions

Chemical science (Cambridge), 2021-10, Vol.12 (4), p.13292-133

2021

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Design of a Hyperpolarized Molecular Probe for Detection of Aminopeptidase N Activity

Angewandte Chemie (International ed.), 2016-01, Vol.55 (5), p.1765-1768

International ed. in English, 2016

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A parallel permeability assay of peptides across artificial membranes and cell monolayers using a fluorogenic reaction

Organic & biomolecular chemistry, 2019-03, Vol.17 (11), p.2887-2891

2019

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Nongenetic control of receptor signaling dynamics using a DNA-based optochemical tool

Chemical communications (Cambridge, England), 2021-06, Vol.57 (48), p.5969-5972

2021

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Design of a 15N Molecular Unit to Achieve Long Retention of Hyperpolarized Spin State

Scientific reports, 2017-01, Vol.7 (1), p.40104-40104, Article 40104

2017

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Amide-to-ester substitution as a stable alternative to N-methylation for increasing membrane permeability in cyclic peptides

Nature communications, 2023-03, Vol.14 (1), p.1416-14, Article 1416

2023

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A Quantum Dot Conjugated Sugar Ball and Its Cellular Uptake. On the Size Effects of Endocytosis in the Subviral Region

Journal of the American Chemical Society, 2004-06, Vol.126 (21), p.6520-6521

2004

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Apt-clean: aptamer-mediated cleavage of extracellular antigens for the inhibition of membrane protein functions

Biomaterials science, 2023-01, Vol.11 (2), p.445-449

2023

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Chemical‐Labeling‐Assisted Detection of Nucleobase Modifications by Quantum‐Tunneling‐Based Single‐Molecule Sensing

Chembiochem : a European journal of chemical biology, 2020-02, Vol.21 (3), p.335-339

2020

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A platform for designing hyperpolarized magnetic resonance chemical probes

Nature communications, 2013-09, Vol.4 (1), p.2411-2411, Article 2411

2013

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In vivo detection of γ-glutamyl-transferase up-regulation in glioma using hyperpolarized γ-glutamyl-[1- 13 C]glycine

Scientific reports, 2020-04, Vol.10 (1), p.6244-6244, Article 6244

2020

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Beta-galactosidase-responsive synthetic biomarker for targeted tumor detection

Chemical communications (Cambridge, England), 2018-10, Vol.54 (83), p.11745-11748

2018

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Design of a 13C Magnetic Resonance Probe Using a Deuterated Methoxy Group as a Long-Lived Hyperpolarization Unit

Angewandte Chemie (International ed.), 2012-10, Vol.51 (40), p.10114-10117

International ed. in English, 2012

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Design, Synthesis, and Evaluation of Highly Sensitive Molecular Probes for Magnetic Resonance Analysis

Transactions of Japanese Society for Medical and Biological Engineering, 2014, Vol.52(Supplement), pp.SY-33-SY-34

Sando, Shinsuke

2014

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Design of Triple-resonance NMR Reporter Assay

Chemistry letters, 2014-12, Vol.43 (12), p.1873-1875

2014

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Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion

Communications biology, 2021-09, Vol.4 (1), p.1041-1041, Article 1041

2021

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Light-Up Hoechst-DNA Aptamer Pair: Generation of an Aptamer-Selective Fluorophore from a Conventional DNA-Staining Dye

Chembiochem : a European journal of chemical biology, 2007-10, Vol.8 (15), p.1795-1803

2007

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Remarkably Size-Regulated Cell Invasion by Artificial Viruses. Saccharide-Dependent Self-Aggregation of Glycoviruses and Its Consequences in Glycoviral Gene Delivery

Journal of the American Chemical Society, 2003-07, Vol.125 (28), p.8465-8475

2003

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A DNA Aptamer That Inhibits the Aberrant Signaling of Fibroblast Growth Factor Receptor in Cancer Cells

JACS Au, 2021-05, Vol.1 (5), p.578-585

2021

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Development of Hyperpolarized NMR Molecular Probes for Biological Applications

Nongenetic Reprogramming of the Ligand Specificity of Growth Factor Receptors by Bispecific DNA Aptamers

Oligonucleotide-Based Mimetics of Hepatocyte Growth Factor

Design of Nuclear Magnetic Resonance Molecular Probes for Hyperpolarized Bioimaging

A comprehensive study on the effect of backbone stereochemistry of a cyclic hexapeptide on membrane permeability and microsomal stability

Design strategy for serine hydroxymethyltransferase probes based on retro-aldol-type reaction

Peptoid-based reprogrammable template for cell-permeable inhibitors of protein-protein interactions

Design of a Hyperpolarized Molecular Probe for Detection of Aminopeptidase N Activity

A parallel permeability assay of peptides across artificial membranes and cell monolayers using a fluorogenic reaction

Nongenetic control of receptor signaling dynamics using a DNA-based optochemical tool

Design of a 15N Molecular Unit to Achieve Long Retention of Hyperpolarized Spin State

Amide-to-ester substitution as a stable alternative to N-methylation for increasing membrane permeability in cyclic peptides

A Quantum Dot Conjugated Sugar Ball and Its Cellular Uptake. On the Size Effects of Endocytosis in the Subviral Region

Apt-clean: aptamer-mediated cleavage of extracellular antigens for the inhibition of membrane protein functions

Chemical‐Labeling‐Assisted Detection of Nucleobase Modifications by Quantum‐Tunneling‐Based Single‐Molecule Sensing

A platform for designing hyperpolarized magnetic resonance chemical probes

In vivo detection of γ-glutamyl-transferase up-regulation in glioma using hyperpolarized γ-glutamyl-[1- 13 C]glycine

Beta-galactosidase-responsive synthetic biomarker for targeted tumor detection

Design of a 13C Magnetic Resonance Probe Using a Deuterated Methoxy Group as a Long-Lived Hyperpolarization Unit

Design, Synthesis, and Evaluation of Highly Sensitive Molecular Probes for Magnetic Resonance Analysis

Design of Triple-resonance NMR Reporter Assay

Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion

Light-Up Hoechst-DNA Aptamer Pair: Generation of an Aptamer-Selective Fluorophore from a Conventional DNA-Staining Dye

Remarkably Size-Regulated Cell Invasion by Artificial Viruses. Saccharide-Dependent Self-Aggregation of Glycoviruses and Its Consequences in Glycoviral Gene Delivery

A DNA Aptamer That Inhibits the Aberrant Signaling of Fibroblast Growth Factor Receptor in Cancer Cells

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