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Intravenous augmentation treatment and lung density in severe α1 antitrypsin deficiency (RAPID): a randomised, double-blind, placebo-controlled trial

The Lancet (British edition), 2015-07, Vol.386 (9991), p.360-368

2015

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Alpha1-Antitrypsin Deficiency

The New England journal of medicine, 2009-06, Vol.360 (26), p.2749-2757

2009

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Clinical trial attitudes among individuals with Alpha-1 antitrypsin deficiency

Respiratory medicine, 2024-08, Vol.229, p.107676-107676, Article 107676

2024

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Scoliosis and Cardiopulmonary Outcomes in Osteogenesis Imperfecta Patients

Spine (Philadelphia, Pa. 1976), 2019-08, Vol.44 (15), p.1057

2019

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Health-related Quality of Life in Alpha-1 Antitrypsin Deficiency-associated Chronic Obstructive Pulmonary Disease

American journal of respiratory and critical care medicine, 2023-11, Vol.208 (10), p.1132

2023

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Randomized, Placebo-Controlled Trials in Alpha-1 Antitrypsin Deficiency

Annals of the American Thoracic Society, 2016-08, Vol.13 Suppl 4 (Supplement_4), p.S370-S373

Sandhaus, Robert A

2016

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Alpha-1-antitrypsin antagonizes COVID-19: a review of the epidemiology, molecular mechanisms, and clinical evidence

Biochemical Society transactions, 2023-06, Vol.51 (3), p.1361

2023

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Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19

Medical hypotheses, 2021-01, Vol.146, p.110394-110394, Article 110394

2021

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The Inhibition of Serine Proteases by Serpins Is Augmented by Negatively Charged Heparin: A Concise Review of Some Clinically Relevant Interactions

International journal of molecular sciences, 2024-02, Vol.25 (3), p.1804

2024

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Long-Term SGRQ Stability in a Cohort of Individuals with Alpha-1 Antitrypsin Deficiency-Associated Lung Disease

International journal of chronic obstructive pulmonary disease, 2024-01, Vol.19, p.889-900

2024

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Prevalence of Cardiovascular Disease and Rate of Major Adverse Cardiovascular Events in Severe Alpha-1 Antitrypsin Deficiency COPD

International journal of chronic obstructive pulmonary disease, 2024-01, Vol.19, p.149-159

2024

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Clinical considerations in individuals with α1-antitrypsin PISZ genotype

The European respiratory journal, 2020-06, Vol.55 (6)

2020

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Characteristics associated with SF-36 in alpha-1 antitrypsin deficiency-associated COPD: a cross-sectional analysis

BMC pulmonary medicine, 2024-03, Vol.24 (1), p.138-138, Article 138

2024

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Neutrophil Elastase-Mediated Lung Disease

Chronic obstructive pulmonary disease, 2013-03, Vol.10 (S1), p.60-63

2013

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Cardiopulmonary Status in Adults with Osteogenesis Imperfecta: Intrinsic Lung Disease May Contribute More Than Scoliosis

Clinical orthopaedics and related research, 2020-12, Vol.478 (12), p.2833-2843

2020

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Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19

Scientific reports, 2022-03, Vol.12 (1), p.5207-5207, Article 5207

2022

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Alpha-1-Antitrypsin Enhances Primary Human Macrophage Immunity Against Non-tuberculous Mycobacteria

Frontiers in immunology, 2019-06, Vol.10, p.1417-1417

2019

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Alpha-1 antitrypsin inhibits fractalkine-mediated monocyte-lung endothelial cell interactions

American journal of physiology. Lung cellular and molecular physiology, 2023-12, Vol.325 (6), p.L711

2023

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Gene Therapy Meets Stem Cells

The New England journal of medicine, 2012-02, Vol.366 (6), p.567-569

Sandhaus, Robert A

2012

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Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression

The Journal of clinical investigation, 2013-12, Vol.123 (12), p.5310-5318

2013

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Lectin Complement Pathway in Emphysema

American journal of respiratory and critical care medicine, 2019-03, Vol.199 (5), p.659-661

2019

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Genotype is associated with smoking and other key health behaviors among individuals with alpha-1 antitrypsin deficiency-associated lung disease

Respiratory medicine, 2018-10, Vol.143, p.48-55

2018

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α1-Antitrypsin Binds to the Glucocorticoid Receptor with Anti-Inflammatory and Antimycobacterial Significance in Macrophages

The Journal of immunology (1950), 2022-11, Vol.209 (9), p.1746-1759

2022

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Managing the Alpha-1 patient in the ICU: Adapting broad critical care strategies in AATD

Journal of critical care, 2019-12, Vol.54, p.212-219

2019

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Author Correction: Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19

Scientific reports, 2022-04, Vol.12 (1), p.6466-6466, Article 6466

2022

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Intravenous augmentation treatment and lung density in severe α1 antitrypsin deficiency (RAPID): a randomised, double-blind, placebo-controlled trial

Alpha1-Antitrypsin Deficiency

Clinical trial attitudes among individuals with Alpha-1 antitrypsin deficiency

Scoliosis and Cardiopulmonary Outcomes in Osteogenesis Imperfecta Patients

Health-related Quality of Life in Alpha-1 Antitrypsin Deficiency-associated Chronic Obstructive Pulmonary Disease

Randomized, Placebo-Controlled Trials in Alpha-1 Antitrypsin Deficiency

Alpha-1-antitrypsin antagonizes COVID-19: a review of the epidemiology, molecular mechanisms, and clinical evidence

Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19

The Inhibition of Serine Proteases by Serpins Is Augmented by Negatively Charged Heparin: A Concise Review of Some Clinically Relevant Interactions

Long-Term SGRQ Stability in a Cohort of Individuals with Alpha-1 Antitrypsin Deficiency-Associated Lung Disease

Prevalence of Cardiovascular Disease and Rate of Major Adverse Cardiovascular Events in Severe Alpha-1 Antitrypsin Deficiency COPD

Clinical considerations in individuals with α1-antitrypsin PISZ genotype

Characteristics associated with SF-36 in alpha-1 antitrypsin deficiency-associated COPD: a cross-sectional analysis

Neutrophil Elastase-Mediated Lung Disease

Cardiopulmonary Status in Adults with Osteogenesis Imperfecta: Intrinsic Lung Disease May Contribute More Than Scoliosis

Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19

Alpha-1-Antitrypsin Enhances Primary Human Macrophage Immunity Against Non-tuberculous Mycobacteria

Alpha-1 antitrypsin inhibits fractalkine-mediated monocyte-lung endothelial cell interactions

Gene Therapy Meets Stem Cells

Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression

Lectin Complement Pathway in Emphysema

Genotype is associated with smoking and other key health behaviors among individuals with alpha-1 antitrypsin deficiency-associated lung disease

α1-Antitrypsin Binds to the Glucocorticoid Receptor with Anti-Inflammatory and Antimycobacterial Significance in Macrophages

Managing the Alpha-1 patient in the ICU: Adapting broad critical care strategies in AATD

Author Correction: Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19

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