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Ion mobility-mass spectrometry analysis of large protein complexes

Nature protocols, 2008-07, Vol.3 (7), p.1139-1152

2008

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Evidence for Macromolecular Protein Rings in the Absence of Bulk Water

Science (American Association for the Advancement of Science), 2005-12, Vol.310 (5754), p.1658-1661

2005

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An Oligomeric Signaling Platform Formed by the Toll-like Receptor Signal Transducers MyD88 and IRAK-4

The Journal of biological chemistry, 2009-09, Vol.284 (37), p.25404-25411

2009

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Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3

Proceedings of the National Academy of Sciences - PNAS, 2008-11, Vol.105 (47), p.18139-18144

2008

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A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis

PLoS neglected tropical diseases, 2019-05, Vol.13 (5), p.e0007373-e0007373

2019

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Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling

Molecular cancer, 2015-07, Vol.14 (1), p.147-147, Article 147

2015

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Recombinant expression and in vitro characterisation of active Huwentoxin-IV

PloS one, 2013-12, Vol.8 (12), p.e83202

2013

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Structural role of Sfi1p-centrin filaments in budding yeast spindle pole body duplication

The Journal of cell biology, 2006-06, Vol.173 (6), p.867-877

2006

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Engineering neprilysin activity and specificity to create a novel therapeutic for Alzheimer's disease

PloS one, 2014-08, Vol.9 (8), p.e104001

2014

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Phenotypic screening reveals TNFR2 as a promising target for cancer immunotherapy

Oncotarget, 2016-10, Vol.7 (42), p.68278-68291

2016

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501 AZD2796, a myeloid checkpoint inhibitor targeting LILRB2 that promotes pro-inflammatory responses by macrophages and enhances T cell anti-tumor activity

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A562-A562

2023

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Phenotypic screening—the fast track to novel antibody discovery

Drug discovery today. Technologies, 2017-03, Vol.23, p.83-90

2017

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Structural Insight into the Mechanism of Activation of the Toll Receptor by the Dimeric Ligand Spätzle

The Journal of biological chemistry, 2008-05, Vol.283 (21), p.14629-14635

2008

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AU‐rich RNA‐binding induces changes in the quaternary structure of AUH

Proteins, structure, function, and bioinformatics, 2009-05, Vol.75 (2), p.360-372

2009

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Order Changes within Receptor Systems upon Ligand Binding: Receptor Tightening/Oligomerisation and the Interpretation of Binding Parameters

Journal of molecular biology, 2004-07, Vol.340 (2), p.373-383

2004

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Abstract 151: Phenotypic selection screening reveals Annexin A2 as a pancreatic cancer stem cell target

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.151-151

2018

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Topological Models of Heteromeric Protein Assemblies from Mass Spectrometry: Application to the Yeast eIF3:eIF5 Complex

Chemistry & biology, 2015-01, Vol.22 (1), p.117-128

2015

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Identification of the cis‑molecular neighbours of the immune checkpoint protein B7‑H4 in the breast cancer cell‑line SK‑BR‑3 by proteomic proximity labelling

International journal of oncology, 2020-07, Vol.57 (1), p.87-99

2020

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Abstract 4218: Phenotypic selection screening reveals cancer stem cell therapeutic targets

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.4218-4218

2015

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Biosynthesis of the di-meta-hydroxyphenylglycine constituent of the vancomycin-group antibiotic chloroeremomycin

Chemical communications (Cambridge, England), 2001-01 (14), p.1252-1253

2001

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Abstract 4613: Identification of tumor necrosis factor receptor II as a regulatory T cell target for cancer immunotherapy using designed ankyrin repeat protein phenotypic selections

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.4613-4613

2014

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Abstract 974: New target discovery for oncology utilizing phenotypic selection and primary NSCLC patient tumors

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.974-974

2012

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Structural role of Sfi1 p-centrin filaments in budding yeast spindle pole body duplication

The Journal of cell biology, 2006-06, Vol.173 (6), p.867

2006

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Recombinant Expression and In Vitro Characterisation of Active Huwentoxin-IV: e83202

PloS one, 2013-12, Vol.8 (12)

2013

Volltextzugriff (PDF)

Structural Insight into the Mechanism of Activation of the Toll Receptor by the Dimeric Ligand Spaetzle

The Journal of biological chemistry, 2008-05, Vol.283 (21), p.14629-14635

2008

Volltextzugriff (PDF)

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Ion mobility-mass spectrometry analysis of large protein complexes

Evidence for Macromolecular Protein Rings in the Absence of Bulk Water

An Oligomeric Signaling Platform Formed by the Toll-like Receptor Signal Transducers MyD88 and IRAK-4

Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3

A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis

Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling

Recombinant expression and in vitro characterisation of active Huwentoxin-IV

Structural role of Sfi1p-centrin filaments in budding yeast spindle pole body duplication

Engineering neprilysin activity and specificity to create a novel therapeutic for Alzheimer's disease

Phenotypic screening reveals TNFR2 as a promising target for cancer immunotherapy

501 AZD2796, a myeloid checkpoint inhibitor targeting LILRB2 that promotes pro-inflammatory responses by macrophages and enhances T cell anti-tumor activity

Phenotypic screening—the fast track to novel antibody discovery

Structural Insight into the Mechanism of Activation of the Toll Receptor by the Dimeric Ligand Spätzle

AU‐rich RNA‐binding induces changes in the quaternary structure of AUH

Order Changes within Receptor Systems upon Ligand Binding: Receptor Tightening/Oligomerisation and the Interpretation of Binding Parameters

Abstract 151: Phenotypic selection screening reveals Annexin A2 as a pancreatic cancer stem cell target

Topological Models of Heteromeric Protein Assemblies from Mass Spectrometry: Application to the Yeast eIF3:eIF5 Complex

Identification of the cis‑molecular neighbours of the immune checkpoint protein B7‑H4 in the breast cancer cell‑line SK‑BR‑3 by proteomic proximity labelling

Abstract 4218: Phenotypic selection screening reveals cancer stem cell therapeutic targets

Biosynthesis of the di-meta-hydroxyphenylglycine constituent of the vancomycin-group antibiotic chloroeremomycin

Abstract 4613: Identification of tumor necrosis factor receptor II as a regulatory T cell target for cancer immunotherapy using designed ankyrin repeat protein phenotypic selections

Abstract 974: New target discovery for oncology utilizing phenotypic selection and primary NSCLC patient tumors

Structural role of Sfi1 p-centrin filaments in budding yeast spindle pole body duplication

Recombinant Expression and In Vitro Characterisation of Active Huwentoxin-IV: e83202

Structural Insight into the Mechanism of Activation of the Toll Receptor by the Dimeric Ligand Spaetzle

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