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Insights from Mendelian Interferonopathies: Comparison of CANDLE, SAVI with AGS, Monogenic Lupus

Journal of Molecular Medicine, 2016-10, Vol.94 (10), p.1111-1127

2016

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An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome

Nature genetics, 2014-10, Vol.46 (10), p.1140

2014

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Novel proteasome assembly chaperone mutations in PSMG2/PAC2 cause the autoinflammatory interferonopathy CANDLE/PRAAS4

Journal of allergy and clinical immunology, 2019-05, Vol.143 (5), p.1939-1943.e8

2019

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JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies

The Journal of clinical investigation, 2018-07, Vol.128 (7), p.3041-3052

2018

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Pharmacokinetics, Pharmacodynamics, and Proposed Dosing of the Oral JAK1 and JAK2 Inhibitor Baricitinib in Pediatric and Young Adult CANDLE and SAVI Patients

Clinical pharmacology and therapeutics, 2018-08, Vol.104 (2), p.364-373

2018

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Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib

EBioMedicine, 2015-04, Vol.2 (4), p.351-355

2015

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Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19

Nature medicine, 2022-05, Vol.28 (5), p.1050

2022

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Development of Tbet- and CD11c-expressing B cells in a viral infection requires T follicular helper cells outside of germinal centers

Immunity (Cambridge, Mass.), 2022-02, Vol.55 (2), p.290-307.e5

2022

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Type I Interferon–Activated STAT4 Regulation of Follicular Helper T Cell–Dependent Cytokine and Immunoglobulin Production in Lupus

Arthritis & rheumatology (Hoboken, N.J.), 2021-03, Vol.73 (3), p.478-489

2021

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Activation of the NLRP3 Inflammasome Increases the IL-1β Level and Decreases GLUT4 Translocation in Skeletal Muscle during Insulin Resistance

International journal of molecular sciences, 2021-09, Vol.22 (19), p.10212

2021

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The 2021 European Alliance of Associations for Rheumatology/American College of Rheumatology points to consider for diagnosis and management of autoinflammatory type I interferonopathies: CANDLE/PRAAS, SAVI and AGS

Annals of the rheumatic diseases, 2022-05, Vol.81 (5), p.601

2022

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Deficiency of Interleukin-1 Receptor Antagonist (DIRA): Report of the First Indian Patient and a Novel Deletion Affecting IL1RN

Journal of clinical immunology, 2017-07, Vol.37 (5), p.445-451

2017

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Cutting Edge: IL-21 and Tissue-Specific Signals Instruct Tbet+CD11c+ B Cell Development following Viral Infection

The Journal of immunology (1950), 2023-06, Vol.210 (12), p.1861-1865

2023

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Recurrent fevers, progressive lipodystrophy, and annular plaques in a child

Journal of the American Academy of Dermatology, 2019-01, Vol.80 (1), p.291-295

2019

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Inhibition of the proteasome preserves Mitofusin-2 and mitochondrial integrity, protecting cardiomyocytes during ischemia-reperfusion injury

Biochimica et biophysica acta. Molecular basis of disease, 2020-05, Vol.1866 (5), p.165659-165659, Article 165659

2020

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Inhibition of chymotrypsin-like activity of the proteasome by ixazomib prevents mitochondrial dysfunction during myocardial ischemia

PloS one, 2020-05, Vol.15 (5), p.e0233591-e0233591

2020

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Novel Majeed Syndrome–Causing LPIN2 Mutations Link Bone Inflammation to Inflammatory M2 Macrophages and Accelerated Osteoclastogenesis

Arthritis & rheumatology (Hoboken, N.J.), 2021-06, Vol.73 (6), p.1021-1032

2021

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Rash, Fever, and Pulmonary Hypertension in a 6‐Year‐Old Female

Arthritis care & research, 2018-05, Vol.70 (5), p.785-790

2018

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The 2021 European Alliance of Associations for Rheumatology/American College of Rheumatology Points to Consider for Diagnosis and Management of Autoinflammatory Type I Interferonopathies: CANDLE/PRAAS, SAVI, and AGS

Arthritis & rheumatology (Hoboken, N.J.), 2022-05, Vol.74 (5), p.735-751

2022

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Monogenic autoinflammatory diseases: disorders of amplified danger sensing and cytokine dysregulation

Rheumatic diseases clinics of North America, 2013-11, Vol.39 (4), p.701-734

2013

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Cerebrospinal Fluid Cytokines Correlate With Aseptic Meningitis and Blood–Brain Barrier Function in Neonatal‐Onset Multisystem Inflammatory Disease: Central Nervous System Biomarkers in Neonatal‐Onset Multisystem Inflammatory Disease Correlate With Central Nervous System Inflammation

Arthritis & rheumatology (Hoboken, N.J.), 2017-06, Vol.69 (6), p.1325-1336

2017

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Fermentable Carbohydrate Alters Hypothalamic Neuronal Activity and Protects Against the Obesogenic Environment

Obesity (Silver Spring, Md.), 2012-05, Vol.20 (5), p.1016-1023

2012

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Deep immune profiling uncovers novel associations with clinical phenotypes of multisystem inflammatory syndrome in children (MIS-C)

Annals of the rheumatic diseases, 2023-03, Vol.82 (3), p.442

2023

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Dexmedetomidine protects the heart against ischemia-reperfusion injury by an endothelial eNOS/NO dependent mechanism

Pharmacological research, 2016-01, Vol.103, p.318-327

2016

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Failure to thrive, interstitial lung disease, and progressive digital necrosis with onset in infancy

Journal of the American Academy of Dermatology, 2016-01, Vol.74 (1), p.186-189

2016

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Insights from Mendelian Interferonopathies: Comparison of CANDLE, SAVI with AGS, Monogenic Lupus

An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome

Novel proteasome assembly chaperone mutations in PSMG2/PAC2 cause the autoinflammatory interferonopathy CANDLE/PRAAS4

JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies

Pharmacokinetics, Pharmacodynamics, and Proposed Dosing of the Oral JAK1 and JAK2 Inhibitor Baricitinib in Pediatric and Young Adult CANDLE and SAVI Patients

Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib

Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19

Development of Tbet- and CD11c-expressing B cells in a viral infection requires T follicular helper cells outside of germinal centers

Type I Interferon–Activated STAT4 Regulation of Follicular Helper T Cell–Dependent Cytokine and Immunoglobulin Production in Lupus

Activation of the NLRP3 Inflammasome Increases the IL-1β Level and Decreases GLUT4 Translocation in Skeletal Muscle during Insulin Resistance

The 2021 European Alliance of Associations for Rheumatology/American College of Rheumatology points to consider for diagnosis and management of autoinflammatory type I interferonopathies: CANDLE/PRAAS, SAVI and AGS

Deficiency of Interleukin-1 Receptor Antagonist (DIRA): Report of the First Indian Patient and a Novel Deletion Affecting IL1RN

Cutting Edge: IL-21 and Tissue-Specific Signals Instruct Tbet+CD11c+ B Cell Development following Viral Infection

Recurrent fevers, progressive lipodystrophy, and annular plaques in a child

Inhibition of the proteasome preserves Mitofusin-2 and mitochondrial integrity, protecting cardiomyocytes during ischemia-reperfusion injury

Inhibition of chymotrypsin-like activity of the proteasome by ixazomib prevents mitochondrial dysfunction during myocardial ischemia

Novel Majeed Syndrome–Causing LPIN2 Mutations Link Bone Inflammation to Inflammatory M2 Macrophages and Accelerated Osteoclastogenesis

Rash, Fever, and Pulmonary Hypertension in a 6‐Year‐Old Female

The 2021 European Alliance of Associations for Rheumatology/American College of Rheumatology Points to Consider for Diagnosis and Management of Autoinflammatory Type I Interferonopathies: CANDLE/PRAAS, SAVI, and AGS

Monogenic autoinflammatory diseases: disorders of amplified danger sensing and cytokine dysregulation

Cerebrospinal Fluid Cytokines Correlate With Aseptic Meningitis and Blood–Brain Barrier Function in Neonatal‐Onset Multisystem Inflammatory Disease: Central Nervous System Biomarkers in Neonatal‐Onset Multisystem Inflammatory Disease Correlate With Central Nervous System Inflammation

Fermentable Carbohydrate Alters Hypothalamic Neuronal Activity and Protects Against the Obesogenic Environment

Deep immune profiling uncovers novel associations with clinical phenotypes of multisystem inflammatory syndrome in children (MIS-C)

Dexmedetomidine protects the heart against ischemia-reperfusion injury by an endothelial eNOS/NO dependent mechanism

Failure to thrive, interstitial lung disease, and progressive digital necrosis with onset in infancy

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