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Prior activation state shapes the microglia response to antihuman TREM2 in a mouse model of Alzheimer's disease

Proceedings of the National Academy of Sciences - PNAS, 2021-01, Vol.118 (3)

2021

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SRSF1 and PTBP1 Are trans-Acting Factors That Suppress the Formation of a CD33 Splicing Isoform Linked to Alzheimer's Disease Risk

Molecular and cellular biology, 2019-09, Vol.39 (18)

2019

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A novel Tmem119-tdTomato reporter mouse model for studying microglia in the central nervous system

Brain, behavior, and immunity, 2020-01, Vol.83, p.180-191

2020

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High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy

Nature (London), 2013-12, Vol.504 (7479), p.291-295

2013

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Role of Membrane Association and Atg14-Dependent Phosphorylation in Beclin-1-Mediated Autophagy

Molecular and Cellular Biology, 2013-09, Vol.33 (18), p.3675-3688

2013

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A Small Molecule Inhibitor of Redox-Regulated Protein Translocation into Mitochondria

Developmental cell, 2013-04, Vol.25 (1), p.81-92

2013

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Innovation in academic chemical screening: filling the gaps in chemical biology

Current opinion in chemical biology, 2013-06, Vol.17 (3), p.329-338

2013

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Discovery of Small-Molecule CD33 Pre-mRNA Splicing Modulators

ACS medicinal chemistry letters, 2022-01, Vol.13 (1), p.55-62

2022

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Chemogenomic Profiling of Endogenous PARK2 Expression Using a Genome-Edited Coincidence Reporter

ACS chemical biology, 2015-05, Vol.10 (5), p.1188-1197

2015

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Adaptation of a Genetic Screen Reveals an Inhibitor for Mitochondrial Protein Import Component Tim44

The Journal of biological chemistry, 2017-03, Vol.292 (13), p.5429-5442

2017

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Application of Imaging-Based Assays in Microplate Formats for High-Content Screening

Methods in molecular biology (Clifton, N.J.), 2016-01, Vol.1439, p.273

2016

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Substrate specificity of the TIM22 mitochondrial import pathway revealed with small molecule inhibitor of protein translocation

Proceedings of the National Academy of Sciences - PNAS, 2010-05, Vol.107 (21), p.9578-9583

2010

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Reconstitution of the mia40-erv1 oxidative folding pathway for the small tim proteins

Molecular biology of the cell, 2009-08, Vol.20 (15), p.3481-3490

2009

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Using the 2A Protein Coexpression System: Multicistronic 2A Vectors Expressing Gene(s) of Interest and Reporter Proteins

Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1755, p.31

2018

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Data Mining and Computational Modeling of High-Throughput Screening Datasets

Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1755, p.197

2018

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Intravital Imaging of Human Melanoma Cells in the Mouse Ear Skin by Two-Photon Excitation Microscopy

Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1755, p.223

2018

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High-Content Reporter Assays

Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1755, p.179

2018

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High-Throughput Firefly Luciferase Reporter Assays

Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1755, p.19

2018

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Endogenous Locus Reporter Assays

Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1755, p.163

2018

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Gene Expression Analysis by Arylsulfatase Assays in the Green Alga Chlamydomonas reinhardtii

Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1755, p.149

2018

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Genome-Edited Cell Lines for High-Throughput Screening

Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1755, p.1

2018

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Making It All Work: Functional Genomics and Reporter Gene Assays

Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1755, p.89

2018

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Mutations in the RNA Polymerase III Subunit Rpc11p That Decrease RNA 3′ Cleavage Activity Increase 3′-Terminal Oligo(U) Length and La-Dependent tRNA Processing

Molecular and Cellular Biology, 2005-01, Vol.25 (2), p.621-636

2005

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Developing Mammalian Cellular Clock Models Using Firefly Luciferase Reporter

Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1755, p.49

2018

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Using YFP as a Reporter of Gene Expression in the Green Alga Chlamydomonas reinhardtii

Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1755, p.135

2018

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Prior activation state shapes the microglia response to antihuman TREM2 in a mouse model of Alzheimer's disease

SRSF1 and PTBP1 Are trans-Acting Factors That Suppress the Formation of a CD33 Splicing Isoform Linked to Alzheimer's Disease Risk

A novel Tmem119-tdTomato reporter mouse model for studying microglia in the central nervous system

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy

Role of Membrane Association and Atg14-Dependent Phosphorylation in Beclin-1-Mediated Autophagy

A Small Molecule Inhibitor of Redox-Regulated Protein Translocation into Mitochondria

Innovation in academic chemical screening: filling the gaps in chemical biology

Discovery of Small-Molecule CD33 Pre-mRNA Splicing Modulators

Chemogenomic Profiling of Endogenous PARK2 Expression Using a Genome-Edited Coincidence Reporter

Adaptation of a Genetic Screen Reveals an Inhibitor for Mitochondrial Protein Import Component Tim44

Application of Imaging-Based Assays in Microplate Formats for High-Content Screening

Substrate specificity of the TIM22 mitochondrial import pathway revealed with small molecule inhibitor of protein translocation

Reconstitution of the mia40-erv1 oxidative folding pathway for the small tim proteins

Using the 2A Protein Coexpression System: Multicistronic 2A Vectors Expressing Gene(s) of Interest and Reporter Proteins

Data Mining and Computational Modeling of High-Throughput Screening Datasets

Intravital Imaging of Human Melanoma Cells in the Mouse Ear Skin by Two-Photon Excitation Microscopy

High-Content Reporter Assays

High-Throughput Firefly Luciferase Reporter Assays

Endogenous Locus Reporter Assays

Gene Expression Analysis by Arylsulfatase Assays in the Green Alga Chlamydomonas reinhardtii

Genome-Edited Cell Lines for High-Throughput Screening

Making It All Work: Functional Genomics and Reporter Gene Assays

Mutations in the RNA Polymerase III Subunit Rpc11p That Decrease RNA 3′ Cleavage Activity Increase 3′-Terminal Oligo(U) Length and La-Dependent tRNA Processing

Developing Mammalian Cellular Clock Models Using Firefly Luciferase Reporter

Using YFP as a Reporter of Gene Expression in the Green Alga Chlamydomonas reinhardtii

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