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Discovery of an Oral Respiratory Syncytial Virus (RSV) Fusion Inhibitor (GS-5806) and Clinical Proof of Concept in a Human RSV Challenge Study

Journal of medicinal chemistry, 2015-02, Vol.58 (4), p.1630-1643

2015

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A Trimer of Dimers Is the Basic Building Block for Human Immunodeficiency Virus-1 Capsid Assembly

Biochemistry (Easton), 2012-06, Vol.51 (22), p.4416-4428

2012

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Solution Structure of the A4 Domain of Factor XI Sheds Light on the Mechanism of Zymogen Activation

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (40), p.15693-15698

2007

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Solution Structure of Plant Nonspecific Lipid Transfer Protein-2 from Rice (Oryza sativa)

The Journal of biological chemistry, 2002-09, Vol.277 (38), p.35267-35273

2002

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Proline inhibits aggregation during protein refolding

Protein science, 2000-02, Vol.9 (2), p.344-352

2000

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Structural, Biochemical, and Biophysical Characterization of Idelalisib Binding to Phosphoinositide 3-Kinase δ

The Journal of biological chemistry, 2015-03, Vol.290 (13), p.8439-8446

2015

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New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action

The Journal of biological chemistry, 2012-06, Vol.287 (25), p.21189-21203

2012

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GS-5806 inhibits pre- to postfusion conformational changes of the respiratory syncytial virus fusion protein

Antimicrobial agents and chemotherapy, 2015-11, Vol.59 (11), p.7109-7112

2015

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Structural Basis for Activity and Specificity of an Anticoagulant Anti-FXIa Monoclonal Antibody and a Reversal Agent

Structure (London), 2018-02, Vol.26 (2), p.187-198.e4

2018

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Visualizing the Molecular Interactions of a Nucleotide Analog, GS-9148, with HIV-1 Reverse Transcriptase–DNA Complex

Journal of molecular biology, 2010-04, Vol.397 (4), p.967-978

2010

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Dithiothreitol Causes HIV-1 Integrase Dimer Dissociation While Agents Interacting With the Integrase Dimer Interface Promote Dimer Formation

Biochemistry (Easton), 2011-03, Vol.50 (10), p.1567-1581

2011

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Dimer Dissociation and Unfolding Mechanism of Coagulation Factor XI Apple 4 Domain: Spectroscopic and Mutational Analysis

Journal of molecular biology, 2007-03, Vol.367 (2), p.558-573

2007

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Binding Mechanism of Nonspecific Lipid Transfer Proteins and Their Role in Plant Defense

Biochemistry (Easton), 2004-11, Vol.43 (43), p.13628-13636

2004

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Characterization and Structural Analyses of Nonspecific Lipid Transfer Protein 1 from Mung Bean

Biochemistry (Easton), 2005-04, Vol.44 (15), p.5703-5712

2005

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Purification and characterization of a novel 7-kDa non-specific lipid transfer protein-2 from rice ( Oryza sativa)

Biochemical and biophysical research communications, 2002-06, Vol.294 (3), p.535-540

2002

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NMR Structural Analysis and Folding Studies of the Factor XI Apple 4 Domain as a Model for Factor XI Homodimerization

Blood, 2005-11, Vol.106 (11), p.1958-1958

2005

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Identification and Characterization of an Equilibrium Intermediate in the Unfolding Pathway of an All β-Barrel Protein

The Journal of biological chemistry, 2000-11, Vol.275 (45), p.34968-34975

2000

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NMR Structural Analysis of Factor XI Apple 4 Domain

Blood, 2004-11, Vol.104 (11), p.1735-1735

2004

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Structural Events during the Refolding of an All β-Sheet Protein

The Journal of biological chemistry, 2001-02, Vol.276 (6), p.4134-4141

2001

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Characterization and Structural Analyses of Nonspecific Lipid Transfer Protein 1 from Mung Bean

Biochemistry (Easton), 2005-08, Vol.44 (34), p.11646-11646

2005

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Mutagenesis Study on the Zebra Fish SOX9 High-Mobility Group: Comparison of Sequence and Non-Sequence Specific HMG Domains

Biochemistry (Easton), 2003-09, Vol.42 (38), p.11183-11193

2003

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Structural Events during the Refolding of an All Î²-Sheet Protein

The Journal of biological chemistry, 2001-02, Vol.276 (6), p.4134

2001

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Identification and Characterization of an Equilibrium Intermediate in the Unfolding Pathway of an All Î²-Barrel Protein

The Journal of biological chemistry, 2000-11, Vol.275 (45), p.34968

2000

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Protein Folding and β-Sheet Proteins

Journal of the Chinese Chemical Society (Taipei), 2000-10, Vol.47 (5), p.1009-1042

2000

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Nineteenth and twentieth century European mission to India: A reconsideration

Dharmaraj, Jacob Samuel

1990

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Discovery of an Oral Respiratory Syncytial Virus (RSV) Fusion Inhibitor (GS-5806) and Clinical Proof of Concept in a Human RSV Challenge Study

A Trimer of Dimers Is the Basic Building Block for Human Immunodeficiency Virus-1 Capsid Assembly

Solution Structure of the A4 Domain of Factor XI Sheds Light on the Mechanism of Zymogen Activation

Solution Structure of Plant Nonspecific Lipid Transfer Protein-2 from Rice (Oryza sativa)

Proline inhibits aggregation during protein refolding

Structural, Biochemical, and Biophysical Characterization of Idelalisib Binding to Phosphoinositide 3-Kinase δ

New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action

GS-5806 inhibits pre- to postfusion conformational changes of the respiratory syncytial virus fusion protein

Structural Basis for Activity and Specificity of an Anticoagulant Anti-FXIa Monoclonal Antibody and a Reversal Agent

Visualizing the Molecular Interactions of a Nucleotide Analog, GS-9148, with HIV-1 Reverse Transcriptase–DNA Complex

Dithiothreitol Causes HIV-1 Integrase Dimer Dissociation While Agents Interacting With the Integrase Dimer Interface Promote Dimer Formation

Dimer Dissociation and Unfolding Mechanism of Coagulation Factor XI Apple 4 Domain: Spectroscopic and Mutational Analysis

Binding Mechanism of Nonspecific Lipid Transfer Proteins and Their Role in Plant Defense

Characterization and Structural Analyses of Nonspecific Lipid Transfer Protein 1 from Mung Bean

Purification and characterization of a novel 7-kDa non-specific lipid transfer protein-2 from rice ( Oryza sativa)

NMR Structural Analysis and Folding Studies of the Factor XI Apple 4 Domain as a Model for Factor XI Homodimerization

Identification and Characterization of an Equilibrium Intermediate in the Unfolding Pathway of an All β-Barrel Protein

NMR Structural Analysis of Factor XI Apple 4 Domain

Structural Events during the Refolding of an All β-Sheet Protein

Characterization and Structural Analyses of Nonspecific Lipid Transfer Protein 1 from Mung Bean

Mutagenesis Study on the Zebra Fish SOX9 High-Mobility Group: Comparison of Sequence and Non-Sequence Specific HMG Domains

Structural Events during the Refolding of an All Î²-Sheet Protein

Identification and Characterization of an Equilibrium Intermediate in the Unfolding Pathway of an All Î²-Barrel Protein

Protein Folding and β-Sheet Proteins

Nineteenth and twentieth century European mission to India: A reconsideration

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