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Targeting cancer metabolism in the era of precision oncology

Nature reviews. Drug discovery, 2022-02, Vol.21 (2), p.141-162

2022

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Elevated pre-mRNA 3' end processing activity in cancer cells renders vulnerability to inhibition of cleavage and polyadenylation

Nature communications, 2023-08, Vol.14 (1), p.4480-20, Article 4480

2023

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The Natural Stilbenoid (–)-Hopeaphenol Inhibits Cellular Entry of SARS-CoV-2 USA-WA1/2020, B.1.1.7, and B.1.351 Variants

Antimicrobial agents and chemotherapy, 2021-11, Vol.65 (12), p.e0077221-e0077221

2021

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Recent Advances in Metal-Catalyzed Approaches for the Synthesis of Quinazoline Derivatives

Molecules (Basel, Switzerland), 2024-05, Vol.29 (10), p.2353

2024

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Novel Small-Molecule CX3CR1 Antagonist Impairs Metastatic Seeding and Colonization of Breast Cancer Cells

Molecular cancer research, 2016-06, Vol.14 (6), p.518-527

2016

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Increased glucose availability sensitizes pancreatic cancer to chemotherapy

Nature communications, 2023-06, Vol.14 (1), p.3823-13, Article 3823

2023

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Small molecule perturbation of the CAND1-Cullin1-ubiquitin cycle stabilizes p53 and triggers Epstein-Barr virus reactivation

PLoS pathogens, 2017-07, Vol.13 (7), p.e1006517

2017

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Knowledge Based Prediction of Ligand Binding Modes and Rational Inhibitor Design for Kinase Drug Discovery

Journal of medicinal chemistry, 2008-09, Vol.51 (17), p.5149-5171

2008

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Preservation of deep epigastric perforators during anterior component separation technique (ACST) results in equivalent wound complications compared to transversus abdominis release (TAR)

Hernia : the journal of hernias and abdominal wall surgery, 2023-08, Vol.27 (4), p.819-827

2023

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A Novel Inhibitor of HSP70 Induces Mitochondrial Toxicity and Immune Cell Recruitment in Tumors

Cancer research (Chicago, Ill.), 2020-12, Vol.80 (23), p.5270-5281

2020

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Identification of Novel Allosteric Modulators of Glutamate Transporter EAAT2

ACS chemical neuroscience, 2018-03, Vol.9 (3), p.522-534

2018

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Elucidation of the Structure and Synthesis of Neuroprotective Low Molecular Mass Components of the Parawixia bistriata Spider Venom

ACS chemical neuroscience, 2020-06, Vol.11 (11), p.1573-1596

2020

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Functional Characterization of the Dopaminergic Psychostimulant Sydnocarb as an Allosteric Modulator of the Human Dopamine Transporter

Biomedicines, 2021-06, Vol.9 (6), p.634

2021

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Pre-analytical parameters associated with unsuccessful karyotyping in myeloid neoplasm: a study of 421 samples

Brazilian journal of medical and biological research, 2019-01, Vol.52 (2), p.e8194-e8194

2019

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The In-Cell Western immunofluorescence assay to monitor PROTAC mediated protein degradation

Methods in enzymology, 2023-01, Vol.681, p.115-153

2023

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Targeted MDM2 Degradation Reveals a New Vulnerability for p53-Inactivated Triple-Negative Breast Cancer

Cancer discovery, 2023-05, Vol.13 (5), p.1210-1229

2023

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Knowledge-based chemoinformatic approaches to drug discovery

Drug discovery today, 2006-12, Vol.11 (23), p.1107-1114

2006

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Characteristics and outcomes of aplastic anemia in HIV patients: a brief report from the severe aplastic anemia working party of the European Society of Blood and Bone Marrow Transplantation

Bone marrow transplantation (Basingstoke), 2016-02, Vol.51 (2), p.313-315

2016

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Rapid Optimization of the Metabolic Stability of a Human Immunodeficiency Virus Type‑1 Capsid Inhibitor Using a Multistep Computational Workflow

Journal of medicinal chemistry, 2021-04, Vol.64 (7), p.3747-3766

2021

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Selective inhibition of Ph-positive ALL cell growth through kinase-dependent and -independent effects by CDK6-specific PROTACs

Blood, 2020-04, Vol.135 (18), p.1560-1573

2020

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AN OPEN‐LABEL, PHASE 1/2 STUDY OF FRONTLINE BRENTUXIMAB VEDOTIN + ADRIAMYCIN, VINBLASTINE, AND DACARBAZINE IN PAEDIATRIC PATIENTS WITH ADVANCED STAGE HODGKIN LYMPHOMA

Hematological oncology, 2021-06, Vol.39 (S2)

2021

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Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth

Cancer research (Chicago, Ill.), 2021-03, Vol.81 (5), p.1252-1264

2021

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IspH inhibitors kill Gram-negative bacteria and mobilize immune clearance

Nature (London), 2021-01, Vol.589 (7843), p.597-5

2021

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Metabolic control of BRISC-SHMT2 assembly regulates immune signalling

Nature (London), 2019-06, Vol.570 (7760), p.194-199

2019

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Targeting cancer metabolism in the era of precision oncology

Elevated pre-mRNA 3' end processing activity in cancer cells renders vulnerability to inhibition of cleavage and polyadenylation

The Natural Stilbenoid (–)-Hopeaphenol Inhibits Cellular Entry of SARS-CoV-2 USA-WA1/2020, B.1.1.7, and B.1.351 Variants

Recent Advances in Metal-Catalyzed Approaches for the Synthesis of Quinazoline Derivatives

Novel Small-Molecule CX3CR1 Antagonist Impairs Metastatic Seeding and Colonization of Breast Cancer Cells

Increased glucose availability sensitizes pancreatic cancer to chemotherapy

Small molecule perturbation of the CAND1-Cullin1-ubiquitin cycle stabilizes p53 and triggers Epstein-Barr virus reactivation

Knowledge Based Prediction of Ligand Binding Modes and Rational Inhibitor Design for Kinase Drug Discovery

Preservation of deep epigastric perforators during anterior component separation technique (ACST) results in equivalent wound complications compared to transversus abdominis release (TAR)

A Novel Inhibitor of HSP70 Induces Mitochondrial Toxicity and Immune Cell Recruitment in Tumors

Identification of Novel Allosteric Modulators of Glutamate Transporter EAAT2

Elucidation of the Structure and Synthesis of Neuroprotective Low Molecular Mass Components of the Parawixia bistriata Spider Venom

Functional Characterization of the Dopaminergic Psychostimulant Sydnocarb as an Allosteric Modulator of the Human Dopamine Transporter

Pre-analytical parameters associated with unsuccessful karyotyping in myeloid neoplasm: a study of 421 samples

The In-Cell Western immunofluorescence assay to monitor PROTAC mediated protein degradation

Targeted MDM2 Degradation Reveals a New Vulnerability for p53-Inactivated Triple-Negative Breast Cancer

Knowledge-based chemoinformatic approaches to drug discovery

Characteristics and outcomes of aplastic anemia in HIV patients: a brief report from the severe aplastic anemia working party of the European Society of Blood and Bone Marrow Transplantation

Rapid Optimization of the Metabolic Stability of a Human Immunodeficiency Virus Type‑1 Capsid Inhibitor Using a Multistep Computational Workflow

Selective inhibition of Ph-positive ALL cell growth through kinase-dependent and -independent effects by CDK6-specific PROTACs

AN OPEN‐LABEL, PHASE 1/2 STUDY OF FRONTLINE BRENTUXIMAB VEDOTIN + ADRIAMYCIN, VINBLASTINE, AND DACARBAZINE IN PAEDIATRIC PATIENTS WITH ADVANCED STAGE HODGKIN LYMPHOMA

Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth

IspH inhibitors kill Gram-negative bacteria and mobilize immune clearance

Metabolic control of BRISC-SHMT2 assembly regulates immune signalling

Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors

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